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Fifty Years of Aryl Hydrocarbon Receptor Research as Reflected in the Pages of Drug Metabolism and Disposition

Drug metabolism and disposition, 2023-06, Vol.51 (6), p.657-671

Riddick, David S

2023

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NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology

Drug metabolism and disposition, 2013-01, Vol.41 (1), p.12

2013

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Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components

Canadian journal of physiology and pharmacology, 2012-10, Vol.90 (10), p.1354

2012

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Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.279-282

2019

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The aryl hydrocarbon receptor pathway and the response to 3-methylcholanthrene are altered in the liver of adrenalectomized rats

Drug metabolism and disposition, 2011-01, Vol.39 (1), p.83

2011

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Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.543

2008

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Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals

Drug metabolism and disposition, 2004-04, Vol.32 (4), p.367

2004

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Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines

Canadian journal of physiology and pharmacology, 2017-06, Vol.95 (6), p.768

2017

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Glucocorticoid and adrenalectomy effects on the rat aryl hydrocarbon receptor pathway depend on the dosing regimen and post-surgical time

Chemico-biological interactions, 2009-12, Vol.182 (2), p.148-158

2009

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Mechanisms of NADPH - cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line

Canadian journal of physiology and pharmacology, 2020-05, Vol.98 (5), p.267

2020

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Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism

Drug metabolism and disposition, 2013-10, Vol.41 (10), p.1782

2013

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Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor

Biochemical pharmacology, 2006-07, Vol.72 (3), p.267-279

2006

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Cancer chemotherapy and drug metabolism

Drug metabolism and disposition, 2005-08, Vol.33 (8), p.1083

2005

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Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.118-129

2017

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The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.457

2013

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Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene

Drug metabolism and disposition, 2006-09, Vol.34 (9), p.1530

2006

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Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells

Molecular pharmacology, 2013-02, Vol.83 (2), p.377-388

2013

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Loss of hepatic aryl hydrocarbon receptor protein in adrenalectomized rats does not involve altered levels of the receptor's cytoplasmic chaperones

Canadian journal of physiology and pharmacology, 2013-12, Vol.91 (12), p.1154

2013

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Cytochrome P450 2C11 5'-flanking region and promoter mediate in vivo suppression by 3-methylcholanthrene

Drug metabolism and disposition, 2008-09, Vol.36 (9), p.1803

2008

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Cytochrome P450 2C11 5′-flanking region and promoter: Regulation by aromatic hydrocarbons in vitro

Toxicology (Amsterdam), 2008-06, Vol.248 (2), p.104-112

2008

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Regulation of Hepatic CYP3A4 by 3‐Methylcholanthrene in Humanized PXR‐CAR‐CYP3A4/3A7 Mice

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Molecular biology of the aromatic hydrocarbon (dioxin) receptor

Trends in Pharmacological Sciences, 1994-07, Vol.15 (7), p.226-232

1994

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Human NADPH-cytochrome P450 reductase overexpression does not enhance the aerobic cytotoxicity of doxorubicin in human breast cancer cell lines

Cancer research (Chicago, Ill.), 2003-10, Vol.63 (20), p.6914-6919

2003

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Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin

Canadian journal of physiology and pharmacology, 1999-08, Vol.77 (8), p.589

1999

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Suppression of cytochrome P450 2C11 by aromatic hydrocarbons: mechanistic insights from studies of the 5'-flanking region of the CYP2C11 gene

Drug metabolism and disposition, 2002-12, Vol.30 (12), p.1385

2002

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Fifty Years of Aryl Hydrocarbon Receptor Research as Reflected in the Pages of Drug Metabolism and Disposition

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology

Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components

Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice

The aryl hydrocarbon receptor pathway and the response to 3-methylcholanthrene are altered in the liver of adrenalectomized rats

Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells

Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals

Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines

Glucocorticoid and adrenalectomy effects on the rat aryl hydrocarbon receptor pathway depend on the dosing regimen and post-surgical time

Mechanisms of NADPH - cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line

Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism

Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor

Cancer chemotherapy and drug metabolism

Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase

The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene

Regulation of constitutive mouse hepatic cytochromes P450 and growth hormone signaling components by 3-methylcholanthrene

Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells

Loss of hepatic aryl hydrocarbon receptor protein in adrenalectomized rats does not involve altered levels of the receptor's cytoplasmic chaperones

Cytochrome P450 2C11 5'-flanking region and promoter mediate in vivo suppression by 3-methylcholanthrene

Cytochrome P450 2C11 5′-flanking region and promoter: Regulation by aromatic hydrocarbons in vitro

Regulation of Hepatic CYP3A4 by 3‐Methylcholanthrene in Humanized PXR‐CAR‐CYP3A4/3A7 Mice

Molecular biology of the aromatic hydrocarbon (dioxin) receptor

Human NADPH-cytochrome P450 reductase overexpression does not enhance the aerobic cytotoxicity of doxorubicin in human breast cancer cell lines

Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin

Suppression of cytochrome P450 2C11 by aromatic hydrocarbons: mechanistic insights from studies of the 5'-flanking region of the CYP2C11 gene

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