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Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

American journal of physiology. Renal physiology, 2003-08, Vol.285 (2), p.F219-F229

2003

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Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells

Biochemical journal, 2004-07, Vol.381 (Pt 1), p.231-239

2004

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Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

Nature (London), 2007-04, Vol.446 (7136), p.690-694

2007

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Transient exposure to quizartinib mediates sustained inhibition of FLT3 signaling while specifically inducing apoptosis in FLT3-activated leukemia cells

Molecular cancer therapeutics, 2013-04, Vol.12 (4), p.438-447

2013

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Reciprocal Induction of Simple Organogenesis by Mouse Kidney Progenitor Cells in Three-Dimensional Co-Culture

The American journal of pathology, 2012-02, Vol.180 (2), p.819-830

2012

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Mitogenic signaling via platelet-derived growth factor β in metanephric mesenchymal cells

Journal of the American Society of Nephrology, 2007-11, Vol.18 (11), p.2903-2911

2007

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Arachidonic acid-dependent activation of a p22(phox)-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB

Antioxidants & redox signaling, 2006-09, Vol.8 (9-10), p.1497

2006

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Insulin-like Growth Factor-I Induces Renal Cell Hypertrophy via a Calcineurin-dependent Mechanism

The Journal of biological chemistry, 2001-11, Vol.276 (45), p.42492-42500

2001

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Abstract 2640: HBI-2375, a first-in-class IND ready selective MLL1-WDR5 inhibitor, retains desirable preclinical characteristics in solid tumors and in leukemias to be pursued in clinical studies

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.2640-2640

2024

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Abstract C071: HBI-2375, a selective inhibitor of MLL1-WDR5 interaction, possesses desirable preclinical characteristics in solid tumors in combination with checkpoint inhibitors and also in leukemias in the future clinical investigations

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.C071-C071

2023

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Fibronectin induces ureteric bud cells branching and cellular cord and tubule formation

Kidney international, 2004-10, Vol.66 (4), p.1356-1364

2004

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Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

Nature (London), 2009-02, Vol.457 (7231), p.920

2009

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Morphological Insights into the Origin of Glomerular Endothelial and Mesangial Cells and Their Precursors

The journal of histochemistry and cytochemistry, 2003-02, Vol.51 (2), p.141-150

2003

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Specific Cross-talk between Epidermal Growth Factor Receptor and Integrin αvβ5 Promotes Carcinoma Cell Invasion and Metastasis

Cancer research (Chicago, Ill.), 2009-02, Vol.69 (4), p.1383-1391

2009

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Abstract A097: HBI-2438, HUYABIO selective KRASG12C inhibitor with BBB penetration, inhibited tumor growth in a metastatic brain model as single agent and also displayed synergy in combination with HBI-2376 (HUYABIO SHP2 inhibitor) in a CRC PDX model

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A097-A097

2023

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Abstract A098: HBI-2376, HUYABIO clinical stage SHP2 inhibitor, displays efficacy signal in patients with KRAS mutations in early clinical studies

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A098-A098

2023

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Abstract LB526: HBI-2375, a selective inhibitor of MLL1-WDR5 interaction, possesses desirable preclinical characteristics to be pursued in IND enabling studies and future clinical investigations

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.LB526-LB526

2022

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Abstract 1041: HBI-2376, HUYABIO clinical stage SHP2 inhibitor, possess robust in vitro potency and in vivo efficacy in several preclinical tumor models carrying KrasG12C or EGFR mutations

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1041-1041

2022

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Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells

American journal of physiology. Renal physiology, 2002-02, Vol.282 (2), p.F211-F219

2002

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Increased Effect of Interferon γ on PDGF-Induced c-fos Gene Transcription in Glomerular Mesangial Cells: Differential Effect of the Transcriptional Coactivator CBP on STAT1α Activation

Biochemical and biophysical research communications, 2000-07, Vol.273 (3), p.1069-1077

2000

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PDGF receptor-β modulates metanephric mesenchyme chemotaxis induced by PDGF AA

American Journal of Physiology - Renal Physiology, 2009-02, Vol.296 (2), p.F406-F417

2009

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Erratum: Nuclear cytokine-activated IKK[alpha] controls prostate cancer metastasis by repressing Maspin

Nature (London), 2009-02, Vol.457 (7231), p.920

2009

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Nuclear cytokine-activated IKK controls prostate cancer metastasis by repressing Maspin

Nature (London), 2009-02, Vol.457 (7231), p.920-920

2009

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Erratum: Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

Nature (London), 2009-02, Vol.457 (7231), p.920-920

2009

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PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

American journal of physiology. Renal physiology, 2009-02, Vol.296 (2), p.F406-F417

2009

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Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells

Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

Transient exposure to quizartinib mediates sustained inhibition of FLT3 signaling while specifically inducing apoptosis in FLT3-activated leukemia cells

Reciprocal Induction of Simple Organogenesis by Mouse Kidney Progenitor Cells in Three-Dimensional Co-Culture

Mitogenic signaling via platelet-derived growth factor β in metanephric mesenchymal cells

Arachidonic acid-dependent activation of a p22(phox)-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB

Insulin-like Growth Factor-I Induces Renal Cell Hypertrophy via a Calcineurin-dependent Mechanism

Abstract 2640: HBI-2375, a first-in-class IND ready selective MLL1-WDR5 inhibitor, retains desirable preclinical characteristics in solid tumors and in leukemias to be pursued in clinical studies

Abstract C071: HBI-2375, a selective inhibitor of MLL1-WDR5 interaction, possesses desirable preclinical characteristics in solid tumors in combination with checkpoint inhibitors and also in leukemias in the future clinical investigations

Fibronectin induces ureteric bud cells branching and cellular cord and tubule formation

Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

Morphological Insights into the Origin of Glomerular Endothelial and Mesangial Cells and Their Precursors

Specific Cross-talk between Epidermal Growth Factor Receptor and Integrin αvβ5 Promotes Carcinoma Cell Invasion and Metastasis

Abstract A097: HBI-2438, HUYABIO selective KRASG12C inhibitor with BBB penetration, inhibited tumor growth in a metastatic brain model as single agent and also displayed synergy in combination with HBI-2376 (HUYABIO SHP2 inhibitor) in a CRC PDX model

Abstract A098: HBI-2376, HUYABIO clinical stage SHP2 inhibitor, displays efficacy signal in patients with KRAS mutations in early clinical studies

Abstract LB526: HBI-2375, a selective inhibitor of MLL1-WDR5 interaction, possesses desirable preclinical characteristics to be pursued in IND enabling studies and future clinical investigations

Abstract 1041: HBI-2376, HUYABIO clinical stage SHP2 inhibitor, possess robust in vitro potency and in vivo efficacy in several preclinical tumor models carrying KrasG12C or EGFR mutations

Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells

Increased Effect of Interferon γ on PDGF-Induced c-fos Gene Transcription in Glomerular Mesangial Cells: Differential Effect of the Transcriptional Coactivator CBP on STAT1α Activation

PDGF receptor-β modulates metanephric mesenchyme chemotaxis induced by PDGF AA

Erratum: Nuclear cytokine-activated IKK[alpha] controls prostate cancer metastasis by repressing Maspin

Nuclear cytokine-activated IKK controls prostate cancer metastasis by repressing Maspin

Erratum: Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA

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