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Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

Blood cancer journal (New York), 2015-04, Vol.5 (4), p.e307-e307

2015

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Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles

British journal of cancer, 2005-08, Vol.93 (4), p.483-492

2005

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Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

BMC cancer, 2013-08, Vol.13 (1), p.374-374, Article 374

2013

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Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment

Biochemical pharmacology, 2011, Vol.82 (2), p.139-147

2011

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Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Nature communications, 2014, Vol.5 (1), p.3295, Article 3295

2014

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Novel activity of acriflavine against colorectal cancer tumor cells

Cancer science, 2011-12, Vol.102 (12), p.2206-2213

2011

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Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells

Biochemical and biophysical research communications, 2013-02, Vol.431 (2), p.117-123

2013

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Inhibition of proteasome activity, nuclear factor‐KB translocation and cell survival by the antialcoholism drug disulfiram

International journal of cancer, 2006-03, Vol.118 (6), p.1577-1580

2006

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In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency

Journal of chemical information and modeling, 2007-01, Vol.47 (1), p.239-248

2007

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127 Identification of CB3, a novel inhibitor of the ubiquitin-proteasome system

European journal of cancer supplements, 2010, Vol.8 (7), p.47-47

2010

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Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs

Journal of natural products (Washington, D.C.), 2009, Vol.72 (11), p.1969-1974

2009

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Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin‐proteasome system

International journal of cancer, 2009-03, Vol.124 (6), p.1463-1469

2009

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Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

BMC cancer, 2012-07, Vol.12 (1), p.318-318, Article 318

2012

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Evaluation of the antitumor activity of NOV202, a novel microtubule targeting and vascular disrupting agent

Drug design, development and therapy, 2017-01, Vol.11, p.1335-1351

2017

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Identification of Agents that Induce Apoptosis of Multicellular Tumour Spheroids: Enrichment for Mitotic Inhibitors with Hydrophobic Properties

Chemical biology & drug design, 2011-10, Vol.78 (4), p.547-557

2011

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Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

Investigational new drugs, 2013-06, Vol.31 (3), p.587-598

2013

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Image-based screening for the identification of novel proteasome inhibitors

Journal of biomolecular screening, 2007-03, Vol.12 (2), p.203-210

2007

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Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia

Anticancer research, 2012-08, Vol.32 (8), p.3125-3136

2012

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Identification of an inhibitor of the ubiquitin-proteasome system that induces accumulation of polyubiquitinated proteins in the absence of blocking of proteasome function

MedChemComm, 2014, Vol.5 (3), p.376-385

2014

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Identification and Evaluation of Potential Anti-cancer Drugs on Human Neuroendocrine Tumor Cell Lines

Anticancer research, 2006-11, Vol.26 (6B), p.4125-4129

2006

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Identification of CB3, a novel inhibitor of the ubiquitin-proteasome system

EJC SUPPLEMENTS, 2010, Vol.8 (7), p.47

2010

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Novel tyrosine kinase inhibitors are effective in in vitro models of high risk neuroblastoma

CANCER RESEARCH, 2009, Vol.69

2009

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In vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency

ChemInform, 2007-04, Vol.38 (15), p.no-no

2007

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Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles

Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Novel activity of acriflavine against colorectal cancer tumor cells

Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells

Inhibition of proteasome activity, nuclear factor‐KB translocation and cell survival by the antialcoholism drug disulfiram

In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency

127 Identification of CB3, a novel inhibitor of the ubiquitin-proteasome system

Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs

Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin‐proteasome system

Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

Evaluation of the antitumor activity of NOV202, a novel microtubule targeting and vascular disrupting agent

Identification of Agents that Induce Apoptosis of Multicellular Tumour Spheroids: Enrichment for Mitotic Inhibitors with Hydrophobic Properties

Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

Image-based screening for the identification of novel proteasome inhibitors

Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia

Identification of an inhibitor of the ubiquitin-proteasome system that induces accumulation of polyubiquitinated proteins in the absence of blocking of proteasome function

Identification and Evaluation of Potential Anti-cancer Drugs on Human Neuroendocrine Tumor Cell Lines

Identification of CB3, a novel inhibitor of the ubiquitin-proteasome system

Novel tyrosine kinase inhibitors are effective in in vitro models of high risk neuroblastoma

In vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency

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