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Unraveling the mysteries of serum albumin-more than just a serum protein

Frontiers in physiology, 2014, Vol.5, p.299-299

2014

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Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2

The Journal of biological chemistry, 2016-08, Vol.291 (33), p.17303-17318

2016

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The active role of vitamin C in mammalian iron metabolism: Much more than just enhanced iron absorption

Free radical biology & medicine, 2014-10, Vol.75, p.69-83

2014

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CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles

Blood, 2021-10, Vol.138 (16), p.1490-1503

2021

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Molecular pharmacology of ABCG2 and its role in chemoresistance

Molecular pharmacology, 2013-11, Vol.84 (5), p.655-669

2013

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The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6805

2020

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The evolution of iron chelators for the treatment of iron overload disease and cancer

Pharmacological reviews, 2005-12, Vol.57 (4), p.547-583

2005

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Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.15413-15427

2011

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The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells

Biochimica et biophysica acta, 2016-12, Vol.1863 (12), p.2916-2933

2016

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Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

Molecular pharmacology, 2011-10, Vol.80 (4), p.598-609

2011

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The metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer

The Journal of biological chemistry, 2021-12, Vol.297 (6), p.101414-101414, Article 101414

2021

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A Class of Iron Chelators with a Wide Spectrum of Potent Antitumor Activity That Overcomes Resistance to Chemotherapeutics

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (40), p.14901-14906

2006

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Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy

Free radical biology & medicine, 2017-07, Vol.108, p.904-917

2017

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Ironing out the role of the cyclin-dependent kinase inhibitor, p21 in cancer: Novel iron chelating agents to target p21 expression and activity

Free radical biology & medicine, 2019-03, Vol.133, p.276-294

2019

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Gene of the month: Interleukin 6 (IL-6)

Journal of clinical pathology, 2014-11, Vol.67 (11), p.932-937

2014

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The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

Antioxidants & redox signaling, 2013-03, Vol.18 (8), p.874-887

2013

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Targeting cancer by binding iron: Dissecting cellular signaling pathways

Oncotarget, 2015-08, Vol.6 (22), p.18748-18779

2015

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Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans

eLife, 2020-07, Vol.9

2020

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Structure–Activity Relationships of Di-2-pyridylketone, 2‑Benzoylpyridine, and 2‑Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8601-8620

2016

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The good Samaritan glutathione-S-transferase P1: An evolving relationship in nitric oxide metabolism mediated by the direct interactions between multiple effector molecules

Redox biology, 2023-02, Vol.59, p.102568, Article 102568

2023

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The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the “Triad of Death” in cancer by Di-2-pyridylketone thiosemicarbazones

Pharmacological research, 2015-10, Vol.100, p.255-260

2015

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Breaking the cycle: Targeting of NDRG1 to inhibit bi‐directional oncogenic cross‐talk between pancreatic cancer and stroma

The FASEB journal, 2021-02, Vol.35 (2), p.e21347-n/a

2021

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Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10775-10782

2010

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Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter

The Journal of biological chemistry, 2016-02, Vol.291 (8), p.3796-3820

2016

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N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion

PloS one, 2013-02, Vol.8 (2), p.e57273

2013

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Unraveling the mysteries of serum albumin-more than just a serum protein

Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2

The active role of vitamin C in mammalian iron metabolism: Much more than just enhanced iron absorption

CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles

Molecular pharmacology of ABCG2 and its role in chemoresistance

The Role of Extracellular Proteases in Tumor Progression and the Development of Innovative Metal Ion Chelators that Inhibit their Activity

The evolution of iron chelators for the treatment of iron overload disease and cancer

Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1

The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells

Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

The metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer

A Class of Iron Chelators with a Wide Spectrum of Potent Antitumor Activity That Overcomes Resistance to Chemotherapeutics

Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy

Ironing out the role of the cyclin-dependent kinase inhibitor, p21 in cancer: Novel iron chelating agents to target p21 expression and activity

Gene of the month: Interleukin 6 (IL-6)

The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

Targeting cancer by binding iron: Dissecting cellular signaling pathways

Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans

Structure–Activity Relationships of Di-2-pyridylketone, 2‑Benzoylpyridine, and 2‑Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

The good Samaritan glutathione-S-transferase P1: An evolving relationship in nitric oxide metabolism mediated by the direct interactions between multiple effector molecules

The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the “Triad of Death” in cancer by Di-2-pyridylketone thiosemicarbazones

Breaking the cycle: Targeting of NDRG1 to inhibit bi‐directional oncogenic cross‐talk between pancreatic cancer and stroma

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter

N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion

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