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Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies

Redox biology, 2021-05, Vol.41, p.101896-101896, Article 101896

2021

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Regulation and control of nitric oxide (NO) in macrophages: Protecting the “professional killer cell” from its own cytotoxic arsenal via MRP1 and GSTP1

Biochimica et biophysica acta. General subjects, 2017-05, Vol.1861 (5), p.995-999

2017

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Iron chelators as therapeutic agents for the treatment of cancer

Critical reviews in oncology/hematology, 2002-06, Vol.42 (3), p.267-281

Richardson, D.R.

2002

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L-50 - A radical drug mechanism to inhibit tumor growth, metastasis, and resistance: Targeting lysosomal P-glycoprotein

Free radical biology & medicine, 2018-05, Vol.120, p.S19-S19

Richardson, D.R.

2018

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A radical drug mechanism to inhibit tumor growth, metastasis, and resistance: Targeting lysosomal P-glycoprotein

Free radical biology & medicine, 2018-05, Vol.120, p.S19

Richardson, D.R.

2018

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The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis

Carcinogenesis (New York), 2006-11, Vol.27 (11), p.2157-2169

2006

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The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone

Blood, 1997-04, Vol.89 (8), p.3025-3038

1997

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116 Transport of the Anticancer Agent, Dp44mT, via a Receptor-mediated Process

European journal of cancer (1990), 2012-11, Vol.48, p.36-36

2012

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Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo

Carcinogenesis (New York), 2007-10, Vol.28 (10), p.2172-2183

2007

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379 The Anti-tumor Agent, Dp44mT, Differentially Targets the AKT, TGF-beta and ERK Pathways Via the Metastasis Suppressor NDRG1 in Normal Prostate Epithelial Cells and Prostate Cancer Cells

European journal of cancer (1990), 2012-11, Vol.48, p.115-116

2012

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The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis

Biochimica et biophysica acta. Molecular basis of disease, 2020-12, Vol.1866 (12), p.165970, Article 165970

2020

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Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease

Biochimica et biophysica acta, 2015-05, Vol.1853 (5), p.1130-1144

2015

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Antioxidant defense mechanisms and its dysfunctional regulation in the mitochondrial disease, Friedreich's ataxia

Free radical biology & medicine, 2020-11, Vol.159, p.177-188

2020

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Treatment of dilated cardiomyopathy in a mouse model of Friedreich’s ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis

Pharmacological research, 2020-09, Vol.159, p.104994-104994, Article 104994

2020

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Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells

Biochimica et biophysica acta. Molecular basis of disease, 2020-05, Vol.1866 (5), p.165657-165657, Article 165657

2020

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Iron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour Activity

Current drug delivery, 2010-07, Vol.7 (3), p.194-207

2010

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Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

Biochimica et biophysica acta, 2009-07, Vol.1790 (7), p.702-717

2009

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The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response

Biochimica et biophysica acta. Molecular basis of disease, 2019-09, Vol.1865 (9), p.2094-2110

2019

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During mitosis ZEB1 “switches” from being a chromatin-bound epithelial gene repressor, to become a microtubule-associated protein

Biochimica et biophysica acta. Molecular cell research, 2020-07, Vol.1867 (7), p.118673-118673, Article 118673

2020

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Ascorbate-and iron-driven redox activity of Dp44mT and Emodin facilitates peroxidation of micelles and bicelles

Biochimica et biophysica acta. General subjects, 2022-04, Vol.1866 (4), p.130078-130078, Article 130078

2022

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322 Iron chelators that overcome drug resistance

European journal of cancer supplements, 2010, Vol.8 (7), p.103-103

2010

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Glutathione S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells

Free radical biology & medicine, 2014-10, Vol.75, p.14-29

2014

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Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal-epithelial transition in breast cancer cells

Oncogene, 2013-03, Vol.32 (10), p.1240-1251

2013

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The uptake of iron and transferrin by the human malignant melanoma cell

Biochimica et biophysica acta, 1990-06, Vol.1053 (1), p.1-12

1990

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The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells

Biochimica et biophysica acta, 1997-03, Vol.1331 (1), p.1-40

1997

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Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies

Regulation and control of nitric oxide (NO) in macrophages: Protecting the “professional killer cell” from its own cytotoxic arsenal via MRP1 and GSTP1

Iron chelators as therapeutic agents for the treatment of cancer

L-50 - A radical drug mechanism to inhibit tumor growth, metastasis, and resistance: Targeting lysosomal P-glycoprotein

A radical drug mechanism to inhibit tumor growth, metastasis, and resistance: Targeting lysosomal P-glycoprotein

The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis

The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone

116 Transport of the Anticancer Agent, Dp44mT, via a Receptor-mediated Process

Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo

379 The Anti-tumor Agent, Dp44mT, Differentially Targets the AKT, TGF-beta and ERK Pathways Via the Metastasis Suppressor NDRG1 in Normal Prostate Epithelial Cells and Prostate Cancer Cells

The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis

Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease

Antioxidant defense mechanisms and its dysfunctional regulation in the mitochondrial disease, Friedreich's ataxia

Treatment of dilated cardiomyopathy in a mouse model of Friedreich’s ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis

Regulation of autophagy and apoptosis by Dp44mT-mediated activation of AMPK in pancreatic cancer cells

Iron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour Activity

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response

During mitosis ZEB1 “switches” from being a chromatin-bound epithelial gene repressor, to become a microtubule-associated protein

Ascorbate-and iron-driven redox activity of Dp44mT and Emodin facilitates peroxidation of micelles and bicelles

322 Iron chelators that overcome drug resistance

Glutathione S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells

Endoplasmic reticulum protein 29 regulates epithelial cell integrity during the mesenchymal-epithelial transition in breast cancer cells

The uptake of iron and transferrin by the human malignant melanoma cell

The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells

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