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Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning

Toxicology and applied pharmacology, 2010-03, Vol.243 (3), p.300-314

2010

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Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects

Toxicological sciences, 2004-07, Vol.80 (1), p.193-202

2004

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Testing an Aflatoxin B1 Gene Signature in Rat Archival Tissues

Chemical research in toxicology, 2012-05, Vol.25 (5), p.1132-1144

2012

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Application of Toxicogenomics to Toxicology: Basic Concepts in the Analysis of Microarray Data

Toxicologic pathology, 2004-03, Vol.32 (1_suppl), p.72-83

2004

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Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland

Human gene therapy, 2006-11, Vol.17 (11), p.1122-1133

2006

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Gene set enrichment analysis for non-monotone association and multiple experimental categories

BMC bioinformatics, 2008-11, Vol.9 (1), p.481-481, Article 481

2008

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Hepatic Gene Expression Changes throughout the Day in the Fischer Rat: Implications for Toxicogenomic Experiments

Toxicological sciences, 2005-07, Vol.86 (1), p.185-193

2005

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Gene interaction network analysis suggests differences between high and low doses of acetaminophen

Toxicology and applied pharmacology, 2006-09, Vol.215 (3), p.306-316

2006

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A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein

Toxicology (Amsterdam), 2008-11, Vol.253 (1), p.79-88

2008

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Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype

Genome biology, 2008-06, Vol.9 (6), p.R100-R100, Article R100

2008

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Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands

Toxicological sciences, 2011-09, Vol.123 (1), p.247-255

2011

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Hepatic Transcript Levels for Genes Coding for Enzymes Associated with Xenobiotic Metabolism are Altered with Age

Toxicologic pathology, 2007-02, Vol.35 (2), p.242-251

2007

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A review of evidence leading to the prediction that 1,4-butanediol is not a carcinogen

Journal of applied toxicology, 2006-01, Vol.26 (1), p.72-80

Irwin, Richard D.

2006

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Transcriptional Profiling of the Left and Median Liver Lobes of Male F344/N Rats Following Exposure to Acetaminophen

Toxicologic pathology, 2005-01, Vol.33 (1), p.111-117

2005

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Furan-Induced Hepatic Cholangiocarcinomas in Fischer 344 Rats

Toxicologic pathology, 1991-01, Vol.19 (4-2), p.561-570

1991

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Influence of Functional Group Substitutions on the Carcinogenicity of Anthraquinone in Rats and Mice: Analysis of Long-Term Bioassays by the National Cancer Institute and the National Toxicology Program

Journal of toxicology and environmental health. Part B, Critical reviews, 2005-03, Vol.8 (2), p.109-126

2005

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296. Transgene Expression and Neutralizing Antibody Production after Submandibular Gland Administration of AdhAQP1

Molecular therapy, 2006-05, Vol.13 (S1), p.S113-S113

2006

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Variation in the Hepatic Gene Expression in Individual Male Fischer Rats

Toxicologic pathology, 2005-01, Vol.33 (1), p.102-110

2005

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A Multicenter Study of ICU Telemedicine Reengineering of Adult Critical Care

Chest, 2014-03, Vol.145 (3), p.500-507

2014

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ICU Telemedicine Program Financial Outcomes

Chest, 2017-02, Vol.151 (2), p.286-297

2017

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Carcinogenicity of Glycidol in F344 Rats and B6C3F1 Mice

Journal of applied toxicology, 1996-05, Vol.16 (3), p.201-209

1996

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Use of Management Pathways or Algorithms in Children With Chronic Cough

Chest, 2016, Vol.149 (1), p.106-119

2016

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Disposition of [14C]furan in the male F344 rat

Journal of toxicology and environmental health, 1991-10, Vol.34 (2), p.245-257

1991

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Children With Chronic Wet or Productive Cough—Treatment and Investigations

Chest, 2016, Vol.149 (1), p.120-142

2016

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Giants in Chest Medicine

Chest, 2016-10, Vol.150 (4), p.759-760

Irwin, Richard S., MD, Master FCCP

2016

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Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning

Gene Expression Profiling of Rat Livers Reveals Indicators of Potential Adverse Effects

Testing an Aflatoxin B1 Gene Signature in Rat Archival Tissues

Application of Toxicogenomics to Toxicology: Basic Concepts in the Analysis of Microarray Data

Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland

Gene set enrichment analysis for non-monotone association and multiple experimental categories

Hepatic Gene Expression Changes throughout the Day in the Fischer Rat: Implications for Toxicogenomic Experiments

Gene interaction network analysis suggests differences between high and low doses of acetaminophen

A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein

Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype

Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands

Hepatic Transcript Levels for Genes Coding for Enzymes Associated with Xenobiotic Metabolism are Altered with Age

A review of evidence leading to the prediction that 1,4-butanediol is not a carcinogen

Transcriptional Profiling of the Left and Median Liver Lobes of Male F344/N Rats Following Exposure to Acetaminophen

Furan-Induced Hepatic Cholangiocarcinomas in Fischer 344 Rats

Influence of Functional Group Substitutions on the Carcinogenicity of Anthraquinone in Rats and Mice: Analysis of Long-Term Bioassays by the National Cancer Institute and the National Toxicology Program

296. Transgene Expression and Neutralizing Antibody Production after Submandibular Gland Administration of AdhAQP1

Variation in the Hepatic Gene Expression in Individual Male Fischer Rats

A Multicenter Study of ICU Telemedicine Reengineering of Adult Critical Care

ICU Telemedicine Program Financial Outcomes

Carcinogenicity of Glycidol in F344 Rats and B6C3F1 Mice

Use of Management Pathways or Algorithms in Children With Chronic Cough

Disposition of [14C]furan in the male F344 rat

Children With Chronic Wet or Productive Cough—Treatment and Investigations

Giants in Chest Medicine

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