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The therapeutic window of antibody drug conjugates: A dogma in need of revision

Cancer cell, 2022-11, Vol.40 (11), p.1255-1263

2022

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Emerging methods for the production of homogeneous human glycoproteins

Nature chemical biology, 2009-04, Vol.5 (4), p.206-215

2009

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Structure–Activity Relationships of Bis-Intercalating Peptides and Their Application as Antibody–Drug Conjugate Payloads

Journal of medicinal chemistry, 2023-06, Vol.66 (12), p.8288-8309

2023

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A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG-3 Using an Engineered and Evolved Synthase

Angewandte Chemie International Edition, 2012-08, Vol.51 (34), p.8640-8643

International ed. in English, 2012

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Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases

Journal of the American Chemical Society, 2010-08, Vol.132 (30), p.10570-10577

2010

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Glycosphingolipid synthesis employing a combination of recombinant glycosyltransferases and an endoglycoceramidase glycosynthase

Chemical communications (Cambridge, England), 2011-01, Vol.47 (38), p.10806-10808

2011

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7‑Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins

ACS central science, 2021-02, Vol.7 (2), p.345-354

2021

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Designer enzymes for glycosphingolipid synthesis by directed evolution

Nature chemical biology, 2009-06, Vol.5 (7), p.508-514

2009

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Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens

Angewandte Chemie International Edition, 2005-12, Vol.44 (47), p.7725-7729

2005

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The Journey of Antibody-Drug Conjugates: Lessons Learned from 40 Years of Development

Cancer discovery, 2024-11, Vol.14 (11), p.2089-2108

2024

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Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

Molecular cancer therapeutics, 2024-05, Vol.23 (5), p.606-618

2024

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Structural insight into mammalian sialyltransferases

Nature structural & molecular biology, 2009-11, Vol.16 (11), p.1186-1188

2009

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Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

International journal of cancer, 2017-04, Vol.140 (7), p.1597-1608

2017

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Designer enzymes for glycosphingolipid synthesis by directed evolution

Nature chemical biology, 2009-07, Vol.5 (7), p.508-514

2009

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A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG-3 Using an Engineered and Evolved Synthase

Angewandte Chemie, 2012-08, Vol.124 (34), p.8768-8771

2012

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Comprehensive characterization of sphingolipid ceramide N-deacylase for the synthesis and fatty acid remodeling of glycosphingolipids

Applied microbiology and biotechnology, 2015-08, Vol.99 (16), p.6715-6726

2015

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Chemical and Chemoenzymatic Synthesis of S-Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens

Chemistry : a European journal, 2006-01, Vol.12 (3), p.845-858

2006

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S-Linked Ganglioside Analogues for Use in Conjugate Vaccines

Organic letters, 2004-03, Vol.6 (6), p.897-900

2004

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Abstract 3798: A glycan-binding malaria protein provides therapeutic access to cisplatin-resistant bladder cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3798-3798

2016

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Directed evolution of a β-glycosidase from Agrobacterium sp. to enhance its glycosynthase activity toward C3-modified donor sugars

Protein engineering, design and selection, 2012-09, Vol.25 (9), p.465-472

2012

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Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni

The Journal of biological chemistry, 2011-10, Vol.286 (41), p.35922-35932

2011

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A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG‐3 Using an Engineered and Evolved Synthase

Angewandte Chemie, 2012-08, Vol.124 (34), p.8768-8771

2012

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Chemoenzymatic synthesis of GM3 and GM2 gangliosides containing a truncated ceramide functionalized for glycoconjugate synthesis and solid phase applications

Organic & biomolecular chemistry, 2006-01, Vol.4 (1), p.142-154

2006

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The therapeutic window of antibody drug conjugates: A dogma in need of revision

Emerging methods for the production of homogeneous human glycoproteins

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

Structure–Activity Relationships of Bis-Intercalating Peptides and Their Application as Antibody–Drug Conjugate Payloads

A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG-3 Using an Engineered and Evolved Synthase

Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases

Glycosphingolipid synthesis employing a combination of recombinant glycosyltransferases and an endoglycoceramidase glycosynthase

7‑Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins

Designer enzymes for glycosphingolipid synthesis by directed evolution

Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens

The Journey of Antibody-Drug Conjugates: Lessons Learned from 40 Years of Development

Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

An Oncofetal Glycosaminoglycan Modification Provides Therapeutic Access to Cisplatin-resistant Bladder Cancer

Structural insight into mammalian sialyltransferases

Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

Designer enzymes for glycosphingolipid synthesis by directed evolution

A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG-3 Using an Engineered and Evolved Synthase

Comprehensive characterization of sphingolipid ceramide N-deacylase for the synthesis and fatty acid remodeling of glycosphingolipids

Chemical and Chemoenzymatic Synthesis of S-Linked Ganglioside Analogues and Their Protein Conjugates for Use as Immunogens

S-Linked Ganglioside Analogues for Use in Conjugate Vaccines

Abstract 3798: A glycan-binding malaria protein provides therapeutic access to cisplatin-resistant bladder cancer

Directed evolution of a β-glycosidase from Agrobacterium sp. to enhance its glycosynthase activity toward C3-modified donor sugars

Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni

A Chemoenzymatic Total Synthesis of the Neurogenic Starfish Ganglioside LLG‐3 Using an Engineered and Evolved Synthase

Chemoenzymatic synthesis of GM3 and GM2 gangliosides containing a truncated ceramide functionalized for glycoconjugate synthesis and solid phase applications

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