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Designing Non-Peptide Peptidomimetics in the 21st Century: Inhibitors Targeting Conformational Ensembles

Journal of medicinal chemistry, 2002-01, Vol.45 (3), p.541-558

2002

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Discovery of nonpeptide, peptidomimetic peptidase inhibitors that target alternate enzyme active site conformations

Biopolymers, 2002, Vol.66 (2), p.115-125

2002

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Peptidomimetic design

Current opinion in chemical biology, 1998-08, Vol.2 (4), p.441-452

1998

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Synthesis of a Gln-Phe Hydroxy-ethylene Dipeptide Isostere

Organic letters, 2004-12, Vol.6 (25), p.4783-4786

2004

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Temperature dependence of excitonic recombination in lateral epitaxially overgrown InGaN/GaN quantum wells studied with cathodoluminescence

Journal of applied physics, 2004-02, Vol.95 (4), p.1832-1842

2004

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Escherichia coli Methionine Aminopeptidase: Implications of Crystallographic Analyses of the Native, Mutant, and Inhibited Enzymes for the Mechanism of Catalysis

Biochemistry (Easton), 1999-06, Vol.38 (24), p.7678-7688

1999

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Total Synthesis of the Cyclic Biphenyl Ether Peptides K-13 and OF4949-III via SNAr Macrocyclization of Peptidyl Ruthenium π-Arene Complexes

Journal of the American Chemical Society, 1997-07, Vol.119 (28), p.6488-6495

1997

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From Peptides to Non-Peptide Peptidomimetics: Design and Synthesis of New Piperidine Inhibitors of Aspartic Peptidases

Organic letters, 2001-07, Vol.3 (15), p.2317-2320

2001

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Lateral epitaxy overgrowth of GaN with NH3 flow rate modulation

Applied physics letters, 2000-09, Vol.77 (10), p.1496-1498

2000

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Two Syntheses of the 16- and 17-Membered DEF Ring Systems of Chloropeptin and Complestatin

Organic letters, 1999-11, Vol.1 (9), p.1443-1446

1999

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Peptidomimetics derived from natural products

Medicinal research reviews, 1993-05, Vol.13 (3), p.327-384

1993

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Synthesis of a Tripeptide Derivative Containing the Gln-Arg Hydroxyethylene Dipeptide Isostere

Organic letters, 2004-12, Vol.6 (25), p.4779-4782

2004

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Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

Biochemistry (Easton), 1991-06, Vol.30 (25), p.6127-6134

1991

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Synthesis of a Tripeptide Derivative Containing the Phe-Arg Hydroxyethylene Dipeptide Isostere

Organic letters, 2001-03, Vol.3 (6), p.945-948

2001

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Cathodoluminescence imaging and spectroscopy of excited states in InAs self-assembled quantum dots

Journal of applied physics, 2005-06, Vol.97 (12)

2005

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Novel Cyclic Tripeptides and Substituted Aromatic Amino Acids via Ruthenium-Activated SNAr Reactions

Organic letters, 1999-12, Vol.1 (11), p.1819-1822

1999

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Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

Journal of medicinal chemistry, 1980-01, Vol.23 (1), p.27-33

1980

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Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease

The Journal of biological chemistry, 1992-04, Vol.267 (11), p.7258-7262

1992

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Aspartic Protease Inhibitors Designed from Computer-Generated Templates Bind As Predicted

Organic letters, 2001-07, Vol.3 (15), p.2309-2312

2001

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X-Ray Crystallographic Structure of a Complex Between a Synthetic Protease of Human Immunodeficiency Virus 1 and a Substrate-Based Hydroxyethylamine Inhibitor

Proceedings of the National Academy of Sciences - PNAS, 1990-11, Vol.87 (22), p.8805-8809

1990

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Solid-Phase Synthesis of Aspartic Peptidase Inhibitors: 3-Alkoxy-4-Aryl Piperidines

Organic letters, 2001-08, Vol.3 (17), p.2625-2628

2001

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Inhibition of HIV-1 Protease by a Subunit of Didemnaketal A

Journal of the American Chemical Society, 1998-09, Vol.120 (34), p.8893-8894

1998

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Mechanistic Studies on the Inactivation of Papain by Epoxysuccinyl Inhibitors

Journal of medicinal chemistry, 1996-08, Vol.39 (17), p.3357-3366

1996

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GaN growth on Si(111) substrate using oxidized AlAs as an intermediate layer

Applied physics letters, 1997-12, Vol.71 (24), p.3569-3571

1997

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Synthesis of novel cyclic protease inhibitors using Grubbs olefin metathesis

Bioorganic & medicinal chemistry letters, 1998-02, Vol.8 (4), p.357-360

1998

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Designing Non-Peptide Peptidomimetics in the 21st Century: Inhibitors Targeting Conformational Ensembles

Discovery of nonpeptide, peptidomimetic peptidase inhibitors that target alternate enzyme active site conformations

Peptidomimetic design

Synthesis of a Gln-Phe Hydroxy-ethylene Dipeptide Isostere

Temperature dependence of excitonic recombination in lateral epitaxially overgrown InGaN/GaN quantum wells studied with cathodoluminescence

Escherichia coli Methionine Aminopeptidase: Implications of Crystallographic Analyses of the Native, Mutant, and Inhibited Enzymes for the Mechanism of Catalysis

Total Synthesis of the Cyclic Biphenyl Ether Peptides K-13 and OF4949-III via SNAr Macrocyclization of Peptidyl Ruthenium π-Arene Complexes

From Peptides to Non-Peptide Peptidomimetics: Design and Synthesis of New Piperidine Inhibitors of Aspartic Peptidases

Lateral epitaxy overgrowth of GaN with NH3 flow rate modulation

Two Syntheses of the 16- and 17-Membered DEF Ring Systems of Chloropeptin and Complestatin

Peptidomimetics derived from natural products

Synthesis of a Tripeptide Derivative Containing the Gln-Arg Hydroxyethylene Dipeptide Isostere

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

Synthesis of a Tripeptide Derivative Containing the Phe-Arg Hydroxyethylene Dipeptide Isostere

Cathodoluminescence imaging and spectroscopy of excited states in InAs self-assembled quantum dots

Novel Cyclic Tripeptides and Substituted Aromatic Amino Acids via Ruthenium-Activated SNAr Reactions

Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease

Aspartic Protease Inhibitors Designed from Computer-Generated Templates Bind As Predicted

X-Ray Crystallographic Structure of a Complex Between a Synthetic Protease of Human Immunodeficiency Virus 1 and a Substrate-Based Hydroxyethylamine Inhibitor

Solid-Phase Synthesis of Aspartic Peptidase Inhibitors: 3-Alkoxy-4-Aryl Piperidines

Inhibition of HIV-1 Protease by a Subunit of Didemnaketal A

Mechanistic Studies on the Inactivation of Papain by Epoxysuccinyl Inhibitors

GaN growth on Si(111) substrate using oxidized AlAs as an intermediate layer

Synthesis of novel cyclic protease inhibitors using Grubbs olefin metathesis

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