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Anticoagulant and signaling functions of antithrombin

Journal of thrombosis and haemostasis, 2020-12, Vol.18 (12), p.3142-3153

2020

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Antithrombin: An anticoagulant, anti‐inflammatory and antibacterial serpin

Journal of thrombosis and haemostasis, 2020-03, Vol.18 (3), p.528-533

2020

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Activated protein C inhibits high mobility group box 1 signaling in endothelial cells

Blood, 2011-10, Vol.118 (14), p.3952-3959

2011

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Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (11), p.1

2021

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Adenosine Regulates the Proinflammatory Signaling Function of Thrombin in Endothelial Cells

Journal of cellular physiology, 2014-09, Vol.229 (9), p.1292-1300

2014

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The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Blood, 2007-12, Vol.110 (12), p.3909-3916

2007

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Inorganic Polyphosphate Amplifies High Mobility Group Box 1-Mediated Von Willebrand Factor Release and Platelet String Formation on Endothelial Cells

Arteriosclerosis, thrombosis, and vascular biology, 2018-08, Vol.38 (8), p.1868

2018

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Activated protein C inhibits lipopolysaccharide‐mediated acetylation and secretion of high‐mobility group box 1 in endothelial cells

Journal of thrombosis and haemostasis, 2019-05, Vol.17 (5), p.803-817

2019

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Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand

Thrombosis and haemostasis, 2008-07, Vol.100 (1), p.101

2008

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Extracellular Histones Bind Vascular Glycosaminoglycans and Inhibit the Anti-Inflammatory Function of Antithrombin

Cellular physiology and biochemistry, 2021-10, Vol.55 (5), p.605-617

2021

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The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases

International journal of molecular sciences, 2019-04, Vol.20 (7), p.1762

2019

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Protease-activated receptor signalling by coagulation proteases in endothelial cells

Thrombosis and haemostasis, 2014-11, Vol.112 (5), p.876

Rezaie, Alireza R

2014

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Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (8), p.2867-2872

2007

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Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation

Blood, 2015-02, Vol.125 (8), p.1339-1348

2015

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Thrombomodulin Regulation of Mitogen-Activated Protein Kinases

International journal of molecular sciences, 2019-04, Vol.20 (8), p.1851

2019

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Ile73Asn mutation in protein C introduces a new N-linked glycosylation site on the first EGF-domain of protein C and causes thrombosis

Haematologica (Roma), 2020-06, Vol.105 (6), p.1712

2020

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Thrombomodulin Regulates PTEN/AKT Signaling Axis in Endothelial Cells

Arteriosclerosis, thrombosis, and vascular biology, 2024-02, Vol.44 (2), p.352

2024

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Thrombomodulin: a multifunctional receptor modulating the endothelial quiescence

Journal of thrombosis and haemostasis, 2024-04, Vol.22 (4), p.905-914

2024

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Activated Protein C Attenuates Severe Inflammation by Targeting VLA-3high Neutrophil Subpopulation in Mice

The Journal of immunology (1950), 2017-10, Vol.199 (8), p.2930-2936

2017

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Activated protein C inhibits mesothelial-to-mesenchymal transition in experimental peritoneal fibrosis

Journal of thrombosis and haemostasis, 2023-01, Vol.21 (1), p.133-144

2023

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Engineering a Disulfide Bond to Stabilize the Calcium-binding Loop of Activated Protein C Eliminates Its Anticoagulant but Not Its Protective Signaling Properties

The Journal of biological chemistry, 2007-03, Vol.282 (12), p.9251-9259

2007

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Residues of the 39-Loop Restrict the Plasma Inhibitor Specificity of Factor IXa

The Journal of biological chemistry, 2013-05, Vol.288 (18), p.12692-12698

2013

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Analysis of protein missense alterations by combining sequence‐ and structure‐based methods

Molecular genetics & genomic medicine, 2020-04, Vol.8 (4), p.e1166-n/a

2020

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Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand

BMB Reports, 2013, 46(11), , pp.544-549

2013

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Thrombomodulin Switches Signaling and Protease-Activated Receptor 1 Cleavage Specificity of Thrombin

Arteriosclerosis, thrombosis, and vascular biology, 2024-03, Vol.44 (3), p.603

2024

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Anticoagulant and signaling functions of antithrombin

Antithrombin: An anticoagulant, anti‐inflammatory and antibacterial serpin

Activated protein C inhibits high mobility group box 1 signaling in endothelial cells

Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells

Adenosine Regulates the Proinflammatory Signaling Function of Thrombin in Endothelial Cells

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Inorganic Polyphosphate Amplifies High Mobility Group Box 1-Mediated Von Willebrand Factor Release and Platelet String Formation on Endothelial Cells

Activated protein C inhibits lipopolysaccharide‐mediated acetylation and secretion of high‐mobility group box 1 in endothelial cells

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand

Extracellular Histones Bind Vascular Glycosaminoglycans and Inhibit the Anti-Inflammatory Function of Antithrombin

The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases

Protease-activated receptor signalling by coagulation proteases in endothelial cells

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation

Thrombomodulin Regulation of Mitogen-Activated Protein Kinases

Ile73Asn mutation in protein C introduces a new N-linked glycosylation site on the first EGF-domain of protein C and causes thrombosis

Thrombomodulin Regulates PTEN/AKT Signaling Axis in Endothelial Cells

Thrombomodulin: a multifunctional receptor modulating the endothelial quiescence

Activated Protein C Attenuates Severe Inflammation by Targeting VLA-3high Neutrophil Subpopulation in Mice

Activated protein C inhibits mesothelial-to-mesenchymal transition in experimental peritoneal fibrosis

Engineering a Disulfide Bond to Stabilize the Calcium-binding Loop of Activated Protein C Eliminates Its Anticoagulant but Not Its Protective Signaling Properties

Residues of the 39-Loop Restrict the Plasma Inhibitor Specificity of Factor IXa

Analysis of protein missense alterations by combining sequence‐ and structure‐based methods

Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand

Thrombomodulin Switches Signaling and Protease-Activated Receptor 1 Cleavage Specificity of Thrombin

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