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Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia

Clinical cancer research, 2016-12, Vol.22 (23), p.5829-5838

2016

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Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors

mAbs, 2021-01, Vol.13 (1), p.1950264-1950264

2021

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Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity

mAbs, 2019-07, Vol.11 (5), p.899-918

2019

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A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells

mAbs, 2014-05, Vol.6 (3), p.727-738

2014

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Anti-LRP/LR specific antibody IgG1-iS18 impedes adhesion and invasion of liver cancer cells

PloS one, 2014-05, Vol.9 (5), p.e96268-e96268

2014

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Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18

PloS one, 2013-06, Vol.8 (6), p.e66297-e66297

2013

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In vitro inhibition of angiogenesis by antibodies directed against the 37kDa/67kDa laminin receptor

PloS one, 2013-03, Vol.8 (3), p.e58888

2013

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Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

PloS one, 2015-11, Vol.10 (11), p.e0141618-e0141618

2015

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Cryopreservation of Natural Killer Cells Pre-Complexed with Innate Cell Engagers

Antibodies (Basel), 2022-02, Vol.11 (1), p.12

2022

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880 Tetravalent, bispecific innate cell engager AFM24 enhances macrophage mediated tumor cell phagocytosis

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A922-A922

2021

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Highly Specific and Effective Targeting of EGFRvIII-Positive Tumors with TandAb Antibodies

Frontiers in oncology, 2017-05, Vol.7, p.100-100

2017

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Invasion of Tumorigenic HT1080 Cells Is Impeded by Blocking or Downregulating the 37-kDa/67-kDa Laminin Receptor

Journal of molecular biology, 2008-05, Vol.378 (3), p.530-539

2008

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AP‐1A and AP‐3A Lysosomal Sorting Functions

Traffic (Copenhagen, Denmark), 2002-10, Vol.3 (10), p.752-761

2002

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Effect of Domain Order on the Activity of Bacterially Produced Bispecific Single-chain Fv Antibodies

Journal of molecular biology, 2003-06, Vol.330 (1), p.99-111

2003

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Cryopreserved CAR-like NK Cells Pre-Complexed with the CD30/CD16A Bispecific Innate Cell Engager (ICE®) AFM13 for the Treatment of CD30 + Malignancies

Blood, 2021-11, Vol.138 (Supplement 1), p.3992-3992

2021

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Abstract P191: The combination of CD16A/EGFR bispecific innate cell engager AFM24 with SNK01 NK cells promotes efficacious targeting and killing of EGFR+ tumor cells

Molecular cancer therapeutics, 2021-12, Vol.20 (12_Supplement), p.P191-P191

2021

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CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells

Cancer immunology research, 2018-05, Vol.6 (5), p.517-527

2018

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Abstract 559: Preclinical characterization of the bispecific EGFR/CD16A innate immune cell engager AFM24 for the treatment of EGFR-expressing solid tumors

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.559-559

2019

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CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages

Blood, 2018-11, Vol.132 (Supplement 1), p.1111-1111

2018

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Abstract 1881: AFM24 is a novel, highly potent, tetravalent bispecific EGFR/CD16A-targeting Innate Cell Engager (ICE®) designed for the treatment of EGFR-positive malignancies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1881-1881

2021

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The Novel Bispecific Innate Cell Engager (ICE®) AFM28 Efficiently Directs Allogeneic NK Cells to CD123+ Leukemic Stem- and Progenitor Cells in AML

Blood, 2022-11, Vol.140 (Supplement 1), p.8815-8816

2022

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Macrophages Escape Inhibition of Major Histocompatibility Complex Class I-Dependent Antigen Presentation by Cytomegalovirus

Journal of Virology, 2000-09, Vol.74 (17), p.7861-7868

2000

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Abstract 5659: AFM24, a bispecific EGFR/CD16A innate cell engager with the potential to overcome resistance to current targeted treatments for EGFR-positive malignancies

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5659-5659

2020

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AFM28, a Novel Bispecific Innate Cell Engager (ICE ®), Designed to Selectively Re-Direct NK Cell Lysis to CD123+ Leukemic Cells in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Blood, 2021-11, Vol.138 (Supplement 1), p.3344-3344

2021

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Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia

A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma

Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors

Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity

A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells

Anti-LRP/LR specific antibody IgG1-iS18 impedes adhesion and invasion of liver cancer cells

Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18

In vitro inhibition of angiogenesis by antibodies directed against the 37kDa/67kDa laminin receptor

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

Cryopreservation of Natural Killer Cells Pre-Complexed with Innate Cell Engagers

880 Tetravalent, bispecific innate cell engager AFM24 enhances macrophage mediated tumor cell phagocytosis

Highly Specific and Effective Targeting of EGFRvIII-Positive Tumors with TandAb Antibodies

Invasion of Tumorigenic HT1080 Cells Is Impeded by Blocking or Downregulating the 37-kDa/67-kDa Laminin Receptor

AP‐1A and AP‐3A Lysosomal Sorting Functions

Effect of Domain Order on the Activity of Bacterially Produced Bispecific Single-chain Fv Antibodies

Cryopreserved CAR-like NK Cells Pre-Complexed with the CD30/CD16A Bispecific Innate Cell Engager (ICE®) AFM13 for the Treatment of CD30 + Malignancies

Abstract P191: The combination of CD16A/EGFR bispecific innate cell engager AFM24 with SNK01 NK cells promotes efficacious targeting and killing of EGFR+ tumor cells

CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells

Abstract 559: Preclinical characterization of the bispecific EGFR/CD16A innate immune cell engager AFM24 for the treatment of EGFR-expressing solid tumors

CD16A-Specific Tetravalent Bispecific Immune Cell Engagers Potently Induce Antibody-Dependent Cellular Phagocytosis (ADCP) on Macrophages

Abstract 1881: AFM24 is a novel, highly potent, tetravalent bispecific EGFR/CD16A-targeting Innate Cell Engager (ICE®) designed for the treatment of EGFR-positive malignancies

The Novel Bispecific Innate Cell Engager (ICE®) AFM28 Efficiently Directs Allogeneic NK Cells to CD123+ Leukemic Stem- and Progenitor Cells in AML

Macrophages Escape Inhibition of Major Histocompatibility Complex Class I-Dependent Antigen Presentation by Cytomegalovirus

Abstract 5659: AFM24, a bispecific EGFR/CD16A innate cell engager with the potential to overcome resistance to current targeted treatments for EGFR-positive malignancies

AFM28, a Novel Bispecific Innate Cell Engager (ICE ®), Designed to Selectively Re-Direct NK Cell Lysis to CD123+ Leukemic Cells in Acute Myeloid Leukemia and Myelodysplastic Syndrome

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