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Applications of CRISPR technology in cellular immunotherapy

Immunological reviews, 2023-11, Vol.320 (1), p.199-216

2023

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Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

Nature immunology, 2019-11, Vol.20 (11), p.1494-1505

2019

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Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

Nature communications, 2022-06, Vol.13 (1), p.3250-12, Article 3250

2022

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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Cell, 2019-08, Vol.178 (5), p.1189-1204.e23

2019

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Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens

Cell research, 2023-05, Vol.33 (5), p.407-410

2023

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CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Cancer discovery, 2020-12, Vol.10 (12), p.1912-1933

2020

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Massively parallel knock-in engineering of human T cells

Nature biotechnology, 2023-09, Vol.41 (9), p.1239-1255

2023

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Heterotypic vaccination responses against SARS-CoV-2 Omicron BA.2

Cell discovery, 2022-07, Vol.8 (1), p.69-69, Article 69

2022

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RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq

Cell chemical biology, 2023-01, Vol.30 (1), p.85-96.e6

2023

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CTLA-4 tail fusion enhances CAR-T antitumor immunity

Nature immunology, 2023-09, Vol.24 (9), p.1499-1510

2023

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In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy

Nature biotechnology, 2024-06

2024

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Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species

Cell reports (Cambridge), 2022-08, Vol.40 (5), p.111160-111160, Article 111160

2022

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The DNA methylation signature of human TCRαβ+CD4−CD8− double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response

Clinical immunology (Orlando, Fla.), 2015-01, Vol.156 (1), p.19-27

2015

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The DNA methylation signature of human TCR alpha beta +CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response

Clinical immunology (Orlando, Fla.), 2015-01, Vol.156 (1), p.19-27

2015

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Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome‐Wide Association Study

Arthritis & rheumatology (Hoboken, N.J.), 2015-05, Vol.67 (5), p.1361-1368

2015

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Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines

Rheumatology (Oxford, England), 2016-04, Vol.55 (4), p.745-754

2016

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Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2

Cell reports. Medicine, 2022-05, Vol.3 (5), p.100634, Article 100634

2022

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Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines

Rheumatology (Oxford, England), 2016-04, Vol.55 (4), p.745-754

2016

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Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo

Cell systems, 2019-02, Vol.8 (2), p.136-151.e7

2019

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Application of CRISPR technology in cellular immunotherapy

Immunological reviews, 2023-07, Vol.320 (1), p.199-216

2023

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AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Nature neuroscience, 2017-10, Vol.20 (10), p.1329-1341

2017

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The genetics of Takayasu arteritis

La Presse médicale (1983), 2017-07, Vol.46 (7-8), p.e179-e187

2017

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Catalytically important residues in the S. cerevisiae lysophospholipid acyltransferase, Lpt1p (605.15)

The FASEB journal, 2014-04, Vol.28 (S1), p.n/a

2014

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Epigenetics and Vasculitis: a Comprehensive Review

Clinical Reviews in Allergy & Immunology, 2016-06, Vol.50 (3), p.357-366

2016

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Saccharomyces cerevisiae lysophospholipid acyltransferase, Lpt1, requires Asp146 and Glu297 for catalysis[S]

Journal of lipid research, 2015-11, Vol.56 (11), p.2143-2150

2015

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Applications of CRISPR technology in cellular immunotherapy

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Massively parallel knock-in engineering of human T cells

Heterotypic vaccination responses against SARS-CoV-2 Omicron BA.2

RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq

CTLA-4 tail fusion enhances CAR-T antitumor immunity

In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy

Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species

The DNA methylation signature of human TCRαβ+CD4−CD8− double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response

The DNA methylation signature of human TCR alpha beta +CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response

Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome‐Wide Association Study

Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines

Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2

Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines

Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo

Application of CRISPR technology in cellular immunotherapy

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

The genetics of Takayasu arteritis

Catalytically important residues in the S. cerevisiae lysophospholipid acyltransferase, Lpt1p (605.15)

Epigenetics and Vasculitis: a Comprehensive Review

Saccharomyces cerevisiae lysophospholipid acyltransferase, Lpt1, requires Asp146 and Glu297 for catalysis[S]

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