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Molecular mechanism of action of metformin: old or new insights?

Diabetologia, 2013-09, Vol.56 (9), p.1898-1906

2013

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Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Circulation research, 2016-08, Vol.119 (5), p.652-665

2016

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Factors affecting resting heart rate in free-living healthy humans

Digital health, 2022-01, Vol.8, p.205520762211290-20552076221129075

2022

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D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a

EMBO reports, 2004-01, Vol.5 (1), p.60-65

2004

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Editorial: Metformin: Beyond Diabetes

Frontiers in endocrinology (Lausanne), 2019-12, Vol.10, p.851-851

2019

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Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)

Diabetes, obesity & metabolism, 2018-12, Vol.20 (12), p.2748-2758

2018

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Metformin selectively targets redox control of complex I energy transduction

Redox biology, 2018-04, Vol.14, p.187-197

2018

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In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA1c lowering is associated with haematological changes

Diabetic medicine, 2021-09, Vol.38 (9), p.e14463-n/a

2021

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Defining Activity Thresholds Triggering a "Stand Hour" for Apple Watch Users: Cross-Sectional Study

JMIR formative research, 2024-06, Vol.8, p.e53806

2024

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Left Ventricular Hypertrophy in Diabetic Cardiomyopathy: A Target for Intervention

Frontiers in cardiovascular medicine, 2021-09, Vol.8, p.746382-746382

2021

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Cellular Responses to the Metal-Binding Properties of Metformin

Diabetes (New York, N.Y.), 2012-06, Vol.61 (6), p.1423-1433

2012

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AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

Molecular metabolism (Germany), 2023-02, Vol.68, p.101661-101661, Article 101661

2023

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Salicylic acid: old and new implications for the treatment of type 2 diabetes?

Diabetology international, 2014-12, Vol.5 (4), p.212-218

2014

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The mechanisms of action of metformin

Diabetologia, 2017-09, Vol.60 (9), p.1577-1585

2017

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Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B

The Journal of biological chemistry, 1999-06, Vol.274 (24), p.17179-17183

1999

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Inflammation as a therapeutic target in heart failure with preserved ejection fraction

Frontiers in cardiovascular medicine, 2023-06, Vol.10, p.1125687-1125687

2023

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Amino acid homeostasis is a target of metformin therapy

Molecular metabolism (Germany), 2023-08, Vol.74, p.101750-101750, Article 101750

2023

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Repurposing Metformin for Cardiovascular Disease

Circulation (New York, N.Y.), 2018-01, Vol.137 (5), p.422-424

2018

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Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence

The Journal of biological chemistry, 1999-06, Vol.274 (24), p.17184-17192

1999

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Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

The EMBO journal, 2002-05, Vol.21 (9), p.2263-2271

2002

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Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Biochemical journal, 2001-03, Vol.354 (Pt 3), p.605-612

2001

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Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes

Metallomics, 2010-01, Vol.2 (3), p.195-203

2010

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The Relationship between Teacher Turnover, Teacher Job Satisfaction and Teacher Perceptions of Leadership Behaviors

Graham, Rena

2023

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Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology

European heart journal, 2018-12, Vol.39 (48), p.4243-4254

2018

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Corrigendum to “Metformin: Still the sweet spot for CV protection in diabetes?” [Curr Opin Pharmacol 54 (2020) 202–208]

Current opinion in pharmacology, 2022-06, Vol.64, p.102070-102070, Article 102070

2022

Volltextzugriff (PDF)

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Molecular mechanism of action of metformin: old or new insights?

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Factors affecting resting heart rate in free-living healthy humans

D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a

Editorial: Metformin: Beyond Diabetes

Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)

Metformin selectively targets redox control of complex I energy transduction

In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA1c lowering is associated with haematological changes

Defining Activity Thresholds Triggering a "Stand Hour" for Apple Watch Users: Cross-Sectional Study

Left Ventricular Hypertrophy in Diabetic Cardiomyopathy: A Target for Intervention

Cellular Responses to the Metal-Binding Properties of Metformin

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

Salicylic acid: old and new implications for the treatment of type 2 diabetes?

The mechanisms of action of metformin

Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B

Inflammation as a therapeutic target in heart failure with preserved ejection fraction

Amino acid homeostasis is a target of metformin therapy

Repurposing Metformin for Cardiovascular Disease

Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes

The Relationship between Teacher Turnover, Teacher Job Satisfaction and Teacher Perceptions of Leadership Behaviors

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology

Corrigendum to “Metformin: Still the sweet spot for CV protection in diabetes?” [Curr Opin Pharmacol 54 (2020) 202–208]

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