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G Protein―Coupled Receptor Deorphanizations

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.127-146

2013

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Pharmacology, Physiology and Genetics of the Neuropeptide S System

Pharmaceuticals (Basel, Switzerland), 2021-04, Vol.14 (5), p.401

2021

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Attenuated G protein signaling and minimal receptor phosphorylation as a biochemical signature of low side-effect opioid analgesics

Scientific reports, 2022-05, Vol.12 (1), p.7154-7154, Article 7154

2022

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Neuropeptide S-Mediated Modulation of Prepulse Inhibition Depends on Age, Gender, Stimulus-Timing, and Attention

Pharmaceuticals (Basel, Switzerland), 2021-05, Vol.14 (5), p.489

2021

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Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a selective antagonist of the neuropeptide S receptor

The Journal of pharmacology and experimental therapeutics, 2008-06, Vol.325 (3), p.893-901

2008

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Pharmacological characterization of human and murine neuropeptide s receptor variants

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1338-1345

2005

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Emerging Paradigms of G Protein-Coupled Receptor Dephosphorylation

Trends in pharmacological sciences (Regular ed.), 2017-07, Vol.38 (7), p.621-636

2017

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Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus

Neuroscience, 2022-08, Vol.496, p.83-95

2022

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HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

Communications biology, 2021-09, Vol.4 (1), p.1070-1070, Article 1070

2021

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A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening

Communications biology, 2022-11, Vol.5 (1), p.1206-1206, Article 1206

2022

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The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice

Peptides (New York, N.Y. : 1980), 2000-07, Vol.21 (7), p.901-906

2000

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In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S

The Journal of pharmacology and experimental therapeutics, 2009-02, Vol.328 (2), p.549-555

2009

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Rapid elucidation of agonist-driven regulation of the neurokinin 1 receptor using a GPCR phosphorylation immunoassay

European journal of pharmacology, 2024-06, Vol.973, p.176587-176587, Article 176587

2024

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Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance

The Journal of pharmacology and experimental therapeutics, 2006-07, Vol.318 (1), p.262-267

2006

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Rapid assessment of G protein signaling of four opioid receptors using a real-time fluorescence-based membrane potential assay

European journal of pharmacology, 2021-01, Vol.890, p.173640, Article 173640

2021

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Molecular fingerprint of neuropeptide s-producing neurons in the mouse brain

Journal of comparative neurology (1911), 2011-07, Vol.519 (10), p.1847-1866

2011

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Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality

Peptides (New York, N.Y. : 1980), 2021-04, Vol.138, p.170506, Article 170506

2021

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The History of N/OFQ and the NOP Receptor

Handbook of experimental pharmacology, 2019-01, Vol.254, p.3-16

2019

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Structure–Activity Relationship Studies on Oxazolo[3,4‑a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4089-4108

2021

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Phylogenetic appearance of neuropeptide S precursor proteins in tetrapods

Peptides (New York, N.Y. : 1980), 2007-04, Vol.28 (4), p.830-837

Reinscheid, Rainer K.

2007

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Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry

Journal of comparative neurology (1911), 2011-07, Vol.519 (10), p.1867-1893

2011

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Neuropeptide S: A transmitter system in the brain regulating fear and anxiety

Neuropharmacology, 2010-01, Vol.58 (1), p.29-34

2010

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Neuropeptide S-Mediated Control of Fear Expression and Extinction: Role of Intercalated GABAergic Neurons in the Amygdala

Neuron (Cambridge, Mass.), 2008-07, Vol.59 (2), p.298-310

2008

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Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain

Neuropsychopharmacology (New York, N.Y.), 2011-03, Vol.36 (4), p.744-752

2011

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Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain

Journal of comparative neurology (1911), 2007-01, Vol.500 (1), p.84-102

2007

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G Protein―Coupled Receptor Deorphanizations

Pharmacology, Physiology and Genetics of the Neuropeptide S System

Attenuated G protein signaling and minimal receptor phosphorylation as a biochemical signature of low side-effect opioid analgesics

Neuropeptide S-Mediated Modulation of Prepulse Inhibition Depends on Age, Gender, Stimulus-Timing, and Attention

Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a selective antagonist of the neuropeptide S receptor

Pharmacological characterization of human and murine neuropeptide s receptor variants

Emerging Paradigms of G Protein-Coupled Receptor Dephosphorylation

Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus

HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening

The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice

In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S

Rapid elucidation of agonist-driven regulation of the neurokinin 1 receptor using a GPCR phosphorylation immunoassay

Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance

Rapid assessment of G protein signaling of four opioid receptors using a real-time fluorescence-based membrane potential assay

Molecular fingerprint of neuropeptide s-producing neurons in the mouse brain

Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality

The History of N/OFQ and the NOP Receptor

Structure–Activity Relationship Studies on Oxazolo[3,4‑a]pyrazine Derivatives Leading to the Discovery of a Novel Neuropeptide S Receptor Antagonist with Potent In Vivo Activity

Phylogenetic appearance of neuropeptide S precursor proteins in tetrapods

Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry

Neuropeptide S: A transmitter system in the brain regulating fear and anxiety

Neuropeptide S-Mediated Control of Fear Expression and Extinction: Role of Intercalated GABAergic Neurons in the Amygdala

Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain

Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain

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