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Adapting to obesity with adipose tissue inflammation

Nature reviews. Endocrinology, 2017-11, Vol.13 (11), p.633

2017

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Developmental trajectories of executive functions from preschool to kindergarten

Developmental science, 2022-09, Vol.25 (5), p.e13236-n/a

2022

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Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Nature medicine, 2015-02, Vol.21 (2), p.159-165

2015

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Culture and Differentiation of Primary Preadipocytes from Mouse Subcutaneous White Adipose Tissue

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2662, p.11

2023

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FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes

Cell reports (Cambridge), 2021-06, Vol.35 (13), p.109331-109331, Article 109331

2021

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TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

Cell metabolism, 2020-12, Vol.32 (6), p.1012-1027.e7

2020

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Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes

Cell metabolism, 2017-07, Vol.26 (1), p.157-170.e7

2017

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Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

Arthritis research & therapy, 2022-07, Vol.24 (1), p.175-13, Article 175

2022

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Death by Dissolution: Sediment Saturation State as a Mortality Factor for Juvenile Bivalves

Limnology and oceanography, 2009-07, Vol.54 (4), p.1037-1047

2009

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Chop / Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice

Science translational medicine, 2021-07, Vol.13 (604)

2021

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Measuring the Rate of Lipolysis in Ex vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

Journal of visualized experiments, 2023-03 (193)

2023

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Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1–mediated p62/sequestosome 1 phosphorylation

Hepatology (Baltimore, Md.), 2018-10, Vol.68 (4), p.1331-1346

2018

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PPARδ as a therapeutic target in metabolic disease

FEBS letters, 2008-01, Vol.582 (1), p.26-31

2008

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Patterns of sleep disturbances across stages of cognitive decline

International journal of geriatric psychiatry, 2023-01, Vol.38 (1), p.e5865-n/a

2023

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RalA controls glucose homeostasis by regulating glucose uptake in brown fat

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7819-7824

2018

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Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1

eLife, 2013-12, Vol.2, p.e01119-e01119

2013

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Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

Nature (London), 2021-11, Vol.599 (7884), p.296-301

2021

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Individualized Coordination and Empowerment for Care Partners of Persons with Dementia (ICECaP): Study rationale and protocol

Contemporary clinical trials, 2024-02, Vol.137, p.107418-107418, Article 107418

2024

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Roles of executive functioning and language in developing low-income preschoolers’ behavior and emotion regulation

Early childhood research quarterly, 2019-01, Vol.49, p.229-240

2019

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A Futile Approach to Fighting Obesity?

Cell, 2015-10, Vol.163 (3), p.539-540

2015

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Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKK ε and Reveal Mechanisms for Selective Inhibition

Molecular pharmacology, 2018-10, Vol.94 (4), p.1210-1219

2018

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YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.15184-15193

2019

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A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis

Nature communications, 2015-01, Vol.6 (1), p.6047-6047, Article 6047

2015

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Neuropsychologists' practice adjustments: The impact of COVID-19

Clinical neuropsychologist, 2021-04, Vol.35 (3), p.490-517

2021

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Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity

Bioorganic & medicinal chemistry, 2018-11, Vol.26 (20), p.5443-5461

2018

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Adapting to obesity with adipose tissue inflammation

Developmental trajectories of executive functions from preschool to kindergarten

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Culture and Differentiation of Primary Preadipocytes from Mouse Subcutaneous White Adipose Tissue

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes

TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes

Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes

Death by Dissolution: Sediment Saturation State as a Mortality Factor for Juvenile Bivalves

Chop / Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice

Measuring the Rate of Lipolysis in Ex vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1–mediated p62/sequestosome 1 phosphorylation

PPARδ as a therapeutic target in metabolic disease

Patterns of sleep disturbances across stages of cognitive decline

RalA controls glucose homeostasis by regulating glucose uptake in brown fat

Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

Individualized Coordination and Empowerment for Care Partners of Persons with Dementia (ICECaP): Study rationale and protocol

Roles of executive functioning and language in developing low-income preschoolers’ behavior and emotion regulation

A Futile Approach to Fighting Obesity?

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKK ε and Reveal Mechanisms for Selective Inhibition

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis

Neuropsychologists' practice adjustments: The impact of COVID-19

Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity

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