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Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876

ChemMedChem, 2016-10, Vol.11 (20), p.2261-2271

2016

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Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

Acta neuropathologica, 2017-04, Vol.133 (4), p.629-644

2017

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Dissociation of Transactivation from Transrepression by a Selective Glucocorticoid Receptor Agonist Leads to Separation of Therapeutic Effects from Side Effects

Proceedings of the National Academy of Sciences - PNAS, 2004-01, Vol.101 (1), p.227-232

2004

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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A

ACS omega, 2020-06, Vol.5 (22), p.13034-13041

2020

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Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index

Molecular and cellular endocrinology, 2007-09, Vol.275 (1), p.109-117

2007

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BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14366-14390

2022

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Identification of novel GLUT inhibitors

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (7), p.1732-1737

2016

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Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate

Bioorganic & medicinal chemistry letters, 2020-08, Vol.30 (16), p.127298, Article 127298

2020

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BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies

Journal of medicinal chemistry, 2021-09, Vol.64 (17), p.12723-12737

2021

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Discovery of new selective glucocorticoid receptor agonist leads

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (3), p.437-442

2017

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Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

Journal of medicinal chemistry, 2017-10, Vol.60 (20), p.8591-8605

2017

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Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5741-5748

2016

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Abstract 4333: Identification and optimization of the first highly selective GLUT-1 inhibitors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4333-4333

2016

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Abstract 3355: Inhibiting glyoxylase 1 as a strategy to target highly glycolytic cancer cells

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.3355-3355

2014

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Cover Picture: Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876 (ChemMedChem 20/2016)

ChemMedChem, 2016-10, Vol.11 (20), p.2240-2240

2016

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Abstract 2645: BAY 1436032: A highly selective, potent and orally available inhibitor of mutant forms of IDH1

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2645-2645

2016

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Discovery of quinolines as selective glucocorticoid receptor agonists

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5835-5838

2010

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Die Wirkungsweise von Medikamenten verstehen: Tabletten, Tropfen und Tinkturen. Hrsg. von Cornelia Bartels, Heike Göllner, Jan Koolman, Edmund Maser, Klaus‐Heinrich Röhm. Wiley‐VCH, Weinheim 2005. 462 Seiten, geb., 24,90 Euro. ISBN 3‐527‐30263‐8

Nachrichten aus der Chemie, 2005-12, Vol.53 (12), p.1267-1267

Rehwinkel, Hartmut

2005

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Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index

Experimental dermatology, 2006-08, Vol.15 (8), p.565-573

2006

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Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds

Expert opinion on therapeutic patents, 2008-03, Vol.18 (3), p.339-352

2008

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Dissociated glucocorticoid receptor ligands: compounds with an improved therapeutic index

Current opinion in investigational drugs (London, England : 2000), 2005-05, Vol.6 (5), p.503

2005

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GR Ligands: Can We Improve the Established Drugs?

ChemMedChem, 2006-08, Vol.1 (8), p.803-805

2006

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Dissociated glucocorticoid receptor ligands

Current opinion in investigational drugs (London, England : 2000), 2004-05, Vol.5 (5), p.524

2004

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Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (12), p.1981-1984

2003

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Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

Dissociation of Transactivation from Transrepression by a Selective Glucocorticoid Receptor Agonist Leads to Separation of Therapeutic Effects from Side Effects

Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A

Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index

BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe

Identification of novel GLUT inhibitors

Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate

BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies

Discovery of new selective glucocorticoid receptor agonist leads

Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators

Abstract 4333: Identification and optimization of the first highly selective GLUT-1 inhibitors

Abstract 3355: Inhibiting glyoxylase 1 as a strategy to target highly glycolytic cancer cells

Cover Picture: Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876 (ChemMedChem 20/2016)

Abstract 2645: BAY 1436032: A highly selective, potent and orally available inhibitor of mutant forms of IDH1

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

Discovery of quinolines as selective glucocorticoid receptor agonists

Die Wirkungsweise von Medikamenten verstehen: Tabletten, Tropfen und Tinkturen. Hrsg. von Cornelia Bartels, Heike Göllner, Jan Koolman, Edmund Maser, Klaus‐Heinrich Röhm. Wiley‐VCH, Weinheim 2005. 462 Seiten, geb., 24,90 Euro. ISBN 3‐527‐30263‐8

Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index

Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds

Dissociated glucocorticoid receptor ligands: compounds with an improved therapeutic index

GR Ligands: Can We Improve the Established Drugs?

Dissociated glucocorticoid receptor ligands

Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors

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