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RET signaling pathway and RET inhibitors in human cancer

Frontiers in oncology, 2022-07, Vol.12, p.932353-932353

2022

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TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Oncogene, 2020-01, Vol.39 (1), p.64-78

2020

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Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Oncogene, 2020-10, Vol.39 (42), p.6589-6605

2020

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Transgenic mouse models of breast cancer

Cancer letters, 2021-09, Vol.516, p.73-83

2021

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Antibody-Drug Conjugates for the Treatment of HER2-Positive Breast Cancer

Genes, 2022-11, Vol.13 (11), p.2065

2022

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Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases

Cancer letters, 2022-08, Vol.540, p.215726-215726, Article 215726

2022

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Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Oncogene, 2024-06, Vol.43 (23), p.1811-1811

2024

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Trk receptor tyrosine kinases in metastasis and cancer therapy

Discovery medicine, 2019-10, Vol.28 (154), p.195-203

2019

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Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers

Cancer letters, 2024-08, Vol.597, p.217023, Article 217023

2024

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NEDD4 degrades TUSC2 to promote glioblastoma progression

Cancer letters, 2022-04, Vol.531, p.124-135

2022

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Tumor Suppressor Candidate 2 (TUSC2): Discovery, Functions, and Cancer Therapy

Cancers, 2023-04, Vol.15 (9), p.2455

2023

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ABI1‐based expression signature predicts breast cancer metastasis and survival

Molecular oncology, 2022-07, Vol.16 (14), p.2632-2657

2022

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Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Oncogene, 2021-03, Vol.40 (12), p.2338-2338

2021

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TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers

Cancers, 2021-05, Vol.13 (10), p.2340

2021

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Abstract 425: Novel transgenic mouse model of tGLI1 for in vivo studies of breast cancer and glioblastoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.425-425

2020

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Abstract 2603: Investigating TUSC2 for its tumor suppressive functions in glioblastoma and its role in gliomagenesis

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2603-2603

2023

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Abstract 4602: Abi1 promotes breast cancer progression by regulating cell-matrix adhesion

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4602-4602

2019

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Abstract 3404: Loss of Abi1 abrogates lung metastasis in the PyMT mouse model of breast cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3404-3404

2017

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Abstract 3769: Intracellular miR-1290 promotes breast cancer stemness in HER2-enriched and triple-negative breast cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3769-3769

2023

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Abstract 1979: JAK2/STAT3 and TrkA pathways are frequently co-activated in triple-negative and HER2-enriched breast cancers and the co-activation correlates with an increased potential of metastasis

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1979-1979

2021

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Abstract 108: Abi1 positively regulates lung metastasis of aggressive breast cancer in PyMT mouse model

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.108-108

2018

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Abstract 1721: Dual targeting of JAK2 and TrkA inhibits breast cancer cell stemness, enhances apoptosis, and delays tumor growth of triple-negative and HER2-enriched breast cancers

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1721-1721

2023

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Abstract 1039: TrkA and JAK2-STAT3 pathway crosstalk promotes breast cancer stem cells in HER2-enriched and triple-negative breast cancers

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1039-1039

2022

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Abstract 92: tGLI1 and IL-6/IL-6R/GP130/STAT3 pathways cooperate to promote breast cancer stem cells and are co-activated in HER2-enriched and triple-negative breast cancers

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.92-92

2022

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RET signaling pathway and RET inhibitors in human cancer

TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Transgenic mouse models of breast cancer

Antibody-Drug Conjugates for the Treatment of HER2-Positive Breast Cancer

Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases

Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Trk receptor tyrosine kinases in metastasis and cancer therapy

Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers

NEDD4 degrades TUSC2 to promote glioblastoma progression

Tumor Suppressor Candidate 2 (TUSC2): Discovery, Functions, and Cancer Therapy

ABI1‐based expression signature predicts breast cancer metastasis and survival

Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Correction: Regua et al. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. Cancers 2021, 13 , 2340

TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers

Abstract 425: Novel transgenic mouse model of tGLI1 for in vivo studies of breast cancer and glioblastoma

Abstract 2603: Investigating TUSC2 for its tumor suppressive functions in glioblastoma and its role in gliomagenesis

Abstract 4602: Abi1 promotes breast cancer progression by regulating cell-matrix adhesion

Abstract 3404: Loss of Abi1 abrogates lung metastasis in the PyMT mouse model of breast cancer

Abstract 3769: Intracellular miR-1290 promotes breast cancer stemness in HER2-enriched and triple-negative breast cancer

Abstract 1979: JAK2/STAT3 and TrkA pathways are frequently co-activated in triple-negative and HER2-enriched breast cancers and the co-activation correlates with an increased potential of metastasis

Abstract 108: Abi1 positively regulates lung metastasis of aggressive breast cancer in PyMT mouse model

Abstract 1721: Dual targeting of JAK2 and TrkA inhibits breast cancer cell stemness, enhances apoptosis, and delays tumor growth of triple-negative and HER2-enriched breast cancers

Abstract 1039: TrkA and JAK2-STAT3 pathway crosstalk promotes breast cancer stem cells in HER2-enriched and triple-negative breast cancers

Abstract 92: tGLI1 and IL-6/IL-6R/GP130/STAT3 pathways cooperate to promote breast cancer stem cells and are co-activated in HER2-enriched and triple-negative breast cancers

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