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A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

British journal of pharmacology, 2011-04, Vol.162 (8), p.1855-1870

2011

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A Faster-Acting and More Potent Form of Tissue Plasminogen Activator

Proceedings of the National Academy of Sciences - PNAS, 1994-04, Vol.91 (9), p.3670-3674

1994

Volltextzugriff (PDF)

Inhibition of arterial thrombosis by a soluble tissue factor mutant and active site-blocked factors IXa and Xa in the guinea pig

Thrombosis and haemostasis, 2001-03, Vol.85 (3), p.475

2001

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New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA

Circulation (New York, N.Y.), 1995-11, Vol.92 (10), p.3032-3040

1995

Volltextzugriff (PDF)

Orally Active Fibrinogen Receptor Antagonists. 2. Amidoximes as Prodrugs of Amidines

Journal of medicinal chemistry, 1996-08, Vol.39 (16), p.3139-3147

1996

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A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent

Blood, 1997-05, Vol.89 (9), p.3219-3227

1997

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A human antibody that binds to the gamma-carboxyglutamic acid domain of factor IX is a potent antithrombotic in vivo

Thrombosis and haemostasis, 1999-09, Vol.82 (3), p.1188

1999

Volltextzugriff (PDF)

A slow clearing, fibrin-specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA)

Thrombosis and haemostasis, 1993-08, Vol.70 (2), p.307

1993

Volltextzugriff (PDF)

Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form

Thrombosis and haemostasis, 1998-01, Vol.79 (1), p.169

1998

Volltextzugriff (PDF)

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen

Thrombosis and haemostasis, 1993-08, Vol.70 (2), p.313

1993

Volltextzugriff (PDF)

A long-half-life and fibrin-specific form of tissue plasminogen activator in rabbit models of embolic stroke and peripheral bleeding

Stroke (1970), 1994-10, Vol.25 (10), p.2072-2078

1994

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The influence of carbohydrate structure on the clearance of recombinant tissue-type plasminogen activator

Thrombosis and haemostasis, 1988-10, Vol.60 (2), p.255

1988

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Comparative thrombolytic properties of tissue-type plasminogen activator and of a plasminogen activator inhibitor-1-resistant glycosylation variant, in a combined arterial and venous thrombosis model in the dog

Thrombosis and haemostasis, 1994-07, Vol.72 (1), p.98

1994

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Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke

The Journal of pharmacology and experimental therapeutics, 1993-01, Vol.264 (1), p.67

1993

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Distinguishing effects of anemia and muscle iron deficiency on exercise bioenergetics in the rat

American journal of physiology: endocrinology and metabolism, 1984-06, Vol.246 (6), p.E535-E543

1984

Volltextzugriff (PDF)

A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.9160-9169

2005

Volltextzugriff (PDF)

An experimental model of intracranial hemorrhage during thrombolytic therapy with t-PA

Thrombosis and haemostasis, 1996-05, Vol.75 (5), p.820

1996

Volltextzugriff (PDF)

Limiting systemic plasminogenolysis reduces the bleeding potential for tissue-type plasminogen activators but not for streptokinase

Thrombosis and haemostasis, 1996-06, Vol.75 (6), p.915

1996

Volltextzugriff (PDF)

A humanized monoclonal antibody targeting the [beta]7 integrin selectively blocks intestinal homing of T lymphocytes

British journal of pharmacology, 2011-04, Vol.162 (8), p.1855

2011

Volltextzugriff (PDF)

Consequences of inhibition of plasma carboxypeptidase B on in vivo thrombolysis, thrombosis and hemostasis

Fibrinolysis & proteolysis, 2000-09, Vol.14 (5), p.305-314

2000

Volltextzugriff (PDF)

D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy

Thrombosis and haemostasis, 1986, Vol.56 (2), p.160

1986

Volltextzugriff (PDF)

Involvement of residues 296–299 in the enzymatic activity of tissue-type plasminogen activator

Protein engineering, 1992-04, Vol.5 (3), p.259-266

1992

Volltextzugriff (PDF)

Work performance in iron deficiency of increasing severity

Journal of applied physiology (1985), 1985-05, Vol.58 (5), p.1477

1985

Volltextzugriff (PDF)

Reduction of Serum IgE by Depletion of the IgE B Cell Lineage- A Novel Approach for the Treatment of Allergic Diseases

Clinical immunology (Orlando, Fla.), 2009-01, Vol.131, p.S31-S31

2009

Volltextzugriff (PDF)

A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding

Arteriosclerosis, thrombosis, and vascular biology, 2002-03, Vol.22 (3), p.517

2002

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A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

A Faster-Acting and More Potent Form of Tissue Plasminogen Activator

Inhibition of arterial thrombosis by a soluble tissue factor mutant and active site-blocked factors IXa and Xa in the guinea pig

New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA

Orally Active Fibrinogen Receptor Antagonists. 2. Amidoximes as Prodrugs of Amidines

A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent

A human antibody that binds to the gamma-carboxyglutamic acid domain of factor IX is a potent antithrombotic in vivo

A slow clearing, fibrin-specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA)

Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen

A long-half-life and fibrin-specific form of tissue plasminogen activator in rabbit models of embolic stroke and peripheral bleeding

The influence of carbohydrate structure on the clearance of recombinant tissue-type plasminogen activator

Comparative thrombolytic properties of tissue-type plasminogen activator and of a plasminogen activator inhibitor-1-resistant glycosylation variant, in a combined arterial and venous thrombosis model in the dog

Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke

Distinguishing effects of anemia and muscle iron deficiency on exercise bioenergetics in the rat

A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo

An experimental model of intracranial hemorrhage during thrombolytic therapy with t-PA

Limiting systemic plasminogenolysis reduces the bleeding potential for tissue-type plasminogen activators but not for streptokinase

A humanized monoclonal antibody targeting the [beta]7 integrin selectively blocks intestinal homing of T lymphocytes

Consequences of inhibition of plasma carboxypeptidase B on in vivo thrombolysis, thrombosis and hemostasis

D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy

Involvement of residues 296–299 in the enzymatic activity of tissue-type plasminogen activator

Work performance in iron deficiency of increasing severity

Reduction of Serum IgE by Depletion of the IgE B Cell Lineage- A Novel Approach for the Treatment of Allergic Diseases

A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding

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