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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Molecular cell, 2011-10, Vol.44 (2), p.265-278

2011

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Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2937-2950

2018

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A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Blood, 2014-08, Vol.124 (7), p.999-1009

2014

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The Role of Neutrophils in Alpha-1 Antitrypsin Deficiency

Annals of the American Thoracic Society, 2016-08, Vol.13 Suppl 4 (Supplement_4), p.S297-S304

2016

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Trikafta Rescues CFTR and Lowers Monocyte P2X7R-induced Inflammasome Activation in Cystic Fibrosis

American journal of respiratory and critical care medicine, 2022-04, Vol.205 (7), p.783-794

2022

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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2441

2022

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The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha‑1 Antitrypsin in Acute and Chronic Inflammatory Conditions

Journal of proteome research, 2014-07, Vol.13 (7), p.3131-3143

2014

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Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic Fibrosis

American journal of respiratory and critical care medicine, 2019-12, Vol.200 (11), p.1381-1391

2019

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The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity

Science translational medicine, 2014-01, Vol.6 (217), p.217ra1

2014

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Citrullination, a novel posttranslational modification of elastin, is involved in COPD pathogenesis

American journal of physiology. Lung cellular and molecular physiology, 2024-10, Vol.327 (4), p.L600-L606

2024

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Effect of elexacaftor/tezacaftor/ivacaftor on airway and systemic inflammation in cystic fibrosis

Thorax, 2023-08, Vol.78 (8), p.835-839

2023

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The vacuolar anti-Pseudomonal activity of neutrophil primary granule peptidyl-arginine deiminase enzymes

Frontiers in immunology, 2024-10, Vol.15, p.1452393

2024

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Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6400

2022

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Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens

FEMS microbiology reviews, 2004-02, Vol.28 (1), p.101-112

2004

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Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences

BioMed research international, 2016-01, Vol.2016 (2016), p.1-14

2016

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The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus

Infection and immunity, 2018-07, Vol.86 (7)

2018

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5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency

Molecular therapy, 2017-06, Vol.25 (6), p.1387-1394

2017

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α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

The Journal of clinical investigation, 2010-12, Vol.120 (12), p.4236-4250

2010

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The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes

Microbiology (Society for General Microbiology), 2011-05, Vol.157 (Pt 5), p.1481-1488

2011

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Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals

Thorax, 2024-09, Vol.79 (9), p.822-833

2024

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Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia

American journal of respiratory and critical care medicine, 2018-05, Vol.197 (10), p.1346-1349

2018

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Neutrophil-Derived Peptidyl Arginine Deiminase Activity Contributes to Pulmonary Emphysema by Enhancing Elastin Degradation

The Journal of immunology (1950), 2024-07, Vol.213 (1), p.75

2024

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Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency

Thorax, 2020-04, Vol.75 (4), p.321-330

2020

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GDPR: an impediment to research?

Irish journal of medical science, 2019-11, Vol.188 (4), p.1129-1135

2019

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Nebulized Hypertonic Saline Decreases IL-8 in Sputum of Patients with Cystic Fibrosis

American journal of respiratory and critical care medicine, 2011-06, Vol.183 (11), p.1517-1523

2011

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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

The Role of Neutrophils in Alpha-1 Antitrypsin Deficiency

Trikafta Rescues CFTR and Lowers Monocyte P2X7R-induced Inflammasome Activation in Cystic Fibrosis

A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha‑1 Antitrypsin in Acute and Chronic Inflammatory Conditions

Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic Fibrosis

The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity

Citrullination, a novel posttranslational modification of elastin, is involved in COPD pathogenesis

Effect of elexacaftor/tezacaftor/ivacaftor on airway and systemic inflammation in cystic fibrosis

The vacuolar anti-Pseudomonal activity of neutrophil primary granule peptidyl-arginine deiminase enzymes

Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease

Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens

Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences

The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus

5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes

Monocyte NLRP3 inflammasome and interleukin-1β activation modulated by alpha-1 antitrypsin therapy in deficient individuals

Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia

Neutrophil-Derived Peptidyl Arginine Deiminase Activity Contributes to Pulmonary Emphysema by Enhancing Elastin Degradation

Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency

GDPR: an impediment to research?

Nebulized Hypertonic Saline Decreases IL-8 in Sputum of Patients with Cystic Fibrosis

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