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Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary glucose excretion in healthy subjects

Diabetes, obesity & metabolism, 2015-04, Vol.17 (4), p.423-425

2015

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Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Diabetes, obesity & metabolism, 2011-08, Vol.13 (8), p.770-773

2011

Volltextzugriff (PDF)

Prediction of the outcome of a phase 3 clinical trial of an antischizophrenic agent (quetiapine fumarate) by simulation with a population pharmacokinetic and pharmacodynamic model

Clinical pharmacology and therapeutics, 2000-11, Vol.68 (5), p.568-577

2000

Volltextzugriff (PDF)

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

British journal of clinical pharmacology, 2006-01, Vol.61 (1), p.58-69

2006

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Publishing Summary Basis of Approval

Clinical pharmacology and therapeutics, 1996-09, Vol.60 (3), p.357-357

Reele, Stots B.

1996

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Gastric antisecretory activity of arbaprostil as affected by gastric pH

Digestive diseases and sciences, 1985-07, Vol.30 (7), p.612-616

REELE, S. B

1985

Volltextzugriff (PDF)

Oral antisecretory activity of prostaglandin E2 in man

Digestive diseases and sciences, 1984-05, Vol.29 (5), p.390-393

1984

Volltextzugriff (PDF)

Clinical Pharmacology and First-Time-in-Man Studies: The FDA Levels the Playing Field

Journal of clinical pharmacology, 1996-03, Vol.36 (3), p.187-188

1996

Volltextzugriff (PDF)

Reassessment of dapsone as a marker of acetylator phenotypes

International journal of clinical pharmacology, therapy, and toxicology, 1991-07, Vol.29 (7), p.262

1991

Volltextzugriff (PDF)

Dose response inhibition in man of meal-stimulated gastric acid secretion by 15(R)-15-methyl prostaglandin E2, given orally

Gut, 1981-09, Vol.22 (9), p.728-731

1981

Volltextzugriff (PDF)

Evaluation of methods of administering tyramine to raise systolic blood pressure

Clinical pharmacology and therapeutics, 1988-08, Vol.44 (2), p.137-144

1988

Volltextzugriff (PDF)

Sorbitol induced diarrheal illness model

International journal of clinical pharmacology, therapy, and toxicology, 1985-08, Vol.23 (8), p.403

1985

Volltextzugriff (PDF)

Absence of cardiac arrhythmias during a very-low-calorie diet with high biological quality protein

International journal of obesity, 1983, Vol.7 (4), p.313

1983

Volltextzugriff (PDF)

The effect of trimoprostil (trimethyldesoxy prostaglandin E ) on the intrauterine pressure in women

Clinical pharmacology and therapeutics, 1988-08, Vol.44 (2), p.179-185

1988

Volltextzugriff (PDF)

Suppression of chronic ventricular arrhythmias with propranolol

Circulation (New York, N.Y.), 1979-10, Vol.60 (4), p.819-827

1979

Volltextzugriff (PDF)

The effects of continuous infusions of prostacyclin-Na (epoprostenol-sodium) on platelet counts, ADP-induced aggregation, and cyclic AMP levels in normal volunteers

Prostaglandins, 1983-08, Vol.26 (2), p.287-302

1983

Volltextzugriff (PDF)

Arbaprostil (15(R)‐15‐methyl PGE2): lack of effect on theophylline metabolism

British journal of clinical pharmacology, 1986-02, Vol.21 (2), p.239-241

1986

Volltextzugriff (PDF)

Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor

The Journal of pharmacology and experimental therapeutics, 1984-04, Vol.229 (1), p.91

1984

Volltextzugriff (PDF)

Travel and risk of venous thrombosis

The Lancet (British edition), 2001-02, Vol.357 (9255), p.553-554

2001

Volltextzugriff (PDF)

Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics

The New England journal of medicine, 1980-04, Vol.302 (16), p.877

1980

Volltextzugriff (PDF)

Lack of Effect of Arbaprostil on the Human Non-Pregnant Uterus

Acta obstetricia et gynecologica Scandinavica, 1985, Vol.64 (8), p.645-647

1985

Volltextzugriff (PDF)

Tocainide therapy for refractory ventricular arrhythmias

The American heart journal, 1980-07, Vol.100 (1), p.15-22

1980

Volltextzugriff (PDF)

Simultaneous modeling of the pharmacokinetics and pharmacodynamics of midazolam and diazepam

Clinical pharmacology and therapeutics, 1995-07, Vol.58 (1), p.35-43

1995

Volltextzugriff (PDF)

Travel and risk of venous thrombosis

The Lancet (British edition), 2001-02, Vol.357 (9255), p.553-553

2001

Volltextzugriff (PDF)

Antiarrhythmic effects of the quaternary propranolol analog that does not induce beta-adrenergic blockade

Clinical pharmacology and therapeutics, 1982-07, Vol.32 (1), p.33-40

1982

Volltextzugriff (PDF)

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Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary glucose excretion in healthy subjects

Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Prediction of the outcome of a phase 3 clinical trial of an antischizophrenic agent (quetiapine fumarate) by simulation with a population pharmacokinetic and pharmacodynamic model

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

Publishing Summary Basis of Approval

Gastric antisecretory activity of arbaprostil as affected by gastric pH

Oral antisecretory activity of prostaglandin E2 in man

Clinical Pharmacology and First-Time-in-Man Studies: The FDA Levels the Playing Field

Reassessment of dapsone as a marker of acetylator phenotypes

Dose response inhibition in man of meal-stimulated gastric acid secretion by 15(R)-15-methyl prostaglandin E2, given orally

Evaluation of methods of administering tyramine to raise systolic blood pressure

Sorbitol induced diarrheal illness model

Absence of cardiac arrhythmias during a very-low-calorie diet with high biological quality protein

The effect of trimoprostil (trimethyldesoxy prostaglandin E ) on the intrauterine pressure in women

Suppression of chronic ventricular arrhythmias with propranolol

The effects of continuous infusions of prostacyclin-Na (epoprostenol-sodium) on platelet counts, ADP-induced aggregation, and cyclic AMP levels in normal volunteers

Arbaprostil (15(R)‐15‐methyl PGE2): lack of effect on theophylline metabolism

Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor

Travel and risk of venous thrombosis

Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics

Lack of Effect of Arbaprostil on the Human Non-Pregnant Uterus

Tocainide therapy for refractory ventricular arrhythmias

Simultaneous modeling of the pharmacokinetics and pharmacodynamics of midazolam and diazepam

Travel and risk of venous thrombosis

Antiarrhythmic effects of the quaternary propranolol analog that does not induce beta-adrenergic blockade

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