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Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary glucose excretion in healthy subjects

Diabetes, obesity & metabolism, 2015-04, Vol.17 (4), p.423-425

2015

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Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Diabetes, obesity & metabolism, 2011-08, Vol.13 (8), p.770-773

2011

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Prediction of the outcome of a phase 3 clinical trial of an antischizophrenic agent (quetiapine fumarate) by simulation with a population pharmacokinetic and pharmacodynamic model

Clinical pharmacology and therapeutics, 2000-11, Vol.68 (5), p.568-577

2000

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Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

British journal of clinical pharmacology, 2006-01, Vol.61 (1), p.58-69

2006

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Publishing Summary Basis of Approval

Clinical pharmacology and therapeutics, 1996-09, Vol.60 (3), p.357-357

Reele, Stots B.

1996

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Gastric antisecretory activity of arbaprostil as affected by gastric pH

Digestive diseases and sciences, 1985-07, Vol.30 (7), p.612-616

REELE, S. B

1985

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Oral antisecretory activity of prostaglandin E2 in man

Digestive diseases and sciences, 1984-05, Vol.29 (5), p.390-393

1984

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Clinical Pharmacology and First-Time-in-Man Studies: The FDA Levels the Playing Field

Journal of clinical pharmacology, 1996-03, Vol.36 (3), p.187-188

1996

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Reassessment of dapsone as a marker of acetylator phenotypes

International journal of clinical pharmacology, therapy, and toxicology, 1991-07, Vol.29 (7), p.262

1991

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Dose response inhibition in man of meal-stimulated gastric acid secretion by 15(R)-15-methyl prostaglandin E2, given orally

Gut, 1981-09, Vol.22 (9), p.728-731

1981

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Absence of cardiac arrhythmias during a very-low-calorie diet with high biological quality protein

International journal of obesity, 1983, Vol.7 (4), p.313

1983

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Sorbitol induced diarrheal illness model

International journal of clinical pharmacology, therapy, and toxicology, 1985-08, Vol.23 (8), p.403

1985

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Evaluation of methods of administering tyramine to raise systolic blood pressure

Clinical pharmacology and therapeutics, 1988-08, Vol.44 (2), p.137-144

1988

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The effect of trimoprostil (trimethyldesoxy prostaglandin E ) on the intrauterine pressure in women

Clinical pharmacology and therapeutics, 1988-08, Vol.44 (2), p.179-185

1988

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Suppression of chronic ventricular arrhythmias with propranolol

Circulation (New York, N.Y.), 1979-10, Vol.60 (4), p.819-827

1979

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The effects of continuous infusions of prostacyclin-Na (epoprostenol-sodium) on platelet counts, ADP-induced aggregation, and cyclic AMP levels in normal volunteers

Prostaglandins, 1983-08, Vol.26 (2), p.287-302

1983

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Arbaprostil (15(R)‐15‐methyl PGE2): lack of effect on theophylline metabolism

British journal of clinical pharmacology, 1986-02, Vol.21 (2), p.239-241

1986

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Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor

The Journal of pharmacology and experimental therapeutics, 1984-04, Vol.229 (1), p.91

1984

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Travel and risk of venous thrombosis

The Lancet (British edition), 2001-02, Vol.357 (9255), p.553-554

2001

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Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics

The New England journal of medicine, 1980-04, Vol.302 (16), p.877-882

1980

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Lack of Effect of Arbaprostil on the Human Non-Pregnant Uterus

Acta obstetricia et gynecologica Scandinavica, 1985, Vol.64 (8), p.645-647

1985

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Tocainide therapy for refractory ventricular arrhythmias

The American heart journal, 1980-07, Vol.100 (1), p.15-22

1980

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Simultaneous modeling of the pharmacokinetics and pharmacodynamics of midazolam and diazepam

Clinical pharmacology and therapeutics, 1995-07, Vol.58 (1), p.35-43

1995

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Travel and risk of venous thrombosis

The Lancet (British edition), 2001-02, Vol.357 (9255), p.553-553

2001

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Antiarrhythmic effects of the quaternary propranolol analog that does not induce beta-adrenergic blockade

Clinical pharmacology and therapeutics, 1982-07, Vol.32 (1), p.33-40

1982

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Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary glucose excretion in healthy subjects

Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Prediction of the outcome of a phase 3 clinical trial of an antischizophrenic agent (quetiapine fumarate) by simulation with a population pharmacokinetic and pharmacodynamic model

Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

Publishing Summary Basis of Approval

Gastric antisecretory activity of arbaprostil as affected by gastric pH

Oral antisecretory activity of prostaglandin E2 in man

Clinical Pharmacology and First-Time-in-Man Studies: The FDA Levels the Playing Field

Reassessment of dapsone as a marker of acetylator phenotypes

Dose response inhibition in man of meal-stimulated gastric acid secretion by 15(R)-15-methyl prostaglandin E2, given orally

Absence of cardiac arrhythmias during a very-low-calorie diet with high biological quality protein

Sorbitol induced diarrheal illness model

Evaluation of methods of administering tyramine to raise systolic blood pressure

The effect of trimoprostil (trimethyldesoxy prostaglandin E ) on the intrauterine pressure in women

Suppression of chronic ventricular arrhythmias with propranolol

The effects of continuous infusions of prostacyclin-Na (epoprostenol-sodium) on platelet counts, ADP-induced aggregation, and cyclic AMP levels in normal volunteers

Arbaprostil (15(R)‐15‐methyl PGE2): lack of effect on theophylline metabolism

Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor

Travel and risk of venous thrombosis

Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics

Lack of Effect of Arbaprostil on the Human Non-Pregnant Uterus

Tocainide therapy for refractory ventricular arrhythmias

Simultaneous modeling of the pharmacokinetics and pharmacodynamics of midazolam and diazepam

Travel and risk of venous thrombosis

Antiarrhythmic effects of the quaternary propranolol analog that does not induce beta-adrenergic blockade

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