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Large-scale network analysis reveals the sequence space architecture of antibody repertoires

Nature communications, 2019-03, Vol.10 (1), p.1321-1321, Article 1321

2019

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Bioinformatic and Statistical Analysis of Adaptive Immune Repertoires

Trends in immunology, 2015-11, Vol.36 (11), p.738-749

2015

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Integrating high‐throughput screening and sequencing for monoclonal antibody discovery and engineering

Immunology, 2018-01, Vol.153 (1), p.31-41

2018

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Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

Cell, 2022-10, Vol.185 (21), p.4008-4022.e14

2022

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Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

Frontiers in immunology, 2018-02, Vol.9, p.224-224

2018

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Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development

Cell reports (Cambridge), 2017-05, Vol.19 (7), p.1467-1478

2017

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A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status

Genome medicine, 2015-05, Vol.7 (1), p.49-49, Article 49

2015

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High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Nucleic acids research, 2018-08, Vol.46 (14), p.7436-7449

2018

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Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire

PloS one, 2014-06, Vol.9 (6), p.e101322-e101322

2014

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Exploiting lymphatic transport and complement activation in nanoparticle vaccines

Nature biotechnology, 2007-10, Vol.25 (10), p.1159-1164

2007

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Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Nature biomedical engineering, 2021-06, Vol.5 (6), p.600-612

2021

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Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim)

Bioinformatics (Oxford, England), 2017-12, Vol.33 (24), p.3938-3946

2017

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speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing

Nature communications, 2022-11, Vol.13 (1), p.6555-16, Article 6555

2022

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Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

Nature communications, 2016-08, Vol.7 (1), p.12535-12535, Article 12535

2016

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Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

Nature biotechnology, 2010-09, Vol.28 (9), p.965-969

2010

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Tcf1 + cells are required to maintain the inflationary T cell pool upon MCMV infection

Nature communications, 2020-05, Vol.11 (1), p.2295-14, Article 2295

2020

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Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

Nature communications, 2020-05, Vol.11 (1), p.2570-2570, Article 2570

2020

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A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients

Frontiers in immunology, 2021-07, Vol.12, p.701085-701085

2021

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Aglycosylated IgG variants expressed in bacteria that selectively bind FcγRI potentiate tumor cell killing by monocyte-dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (2), p.604-609

2010

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Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

PLoS biology, 2019-02, Vol.17 (2), p.e3000164-e3000164

2019

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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

Cell reports (Cambridge), 2020-01, Vol.30 (4), p.1013-1026.e7

2020

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Tracing Antibody Repertoire Evolution by Systems Phylogeny

Frontiers in immunology, 2018-10, Vol.9, p.2149-2149

2018

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Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing

PloS one, 2014-05, Vol.9 (5), p.e96727-e96727

2014

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Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections

Frontiers in immunology, 2022-02, Vol.13, p.782441-782441

2022

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Large-scale network analysis reveals the sequence space architecture of antibody repertoires

Bioinformatic and Statistical Analysis of Adaptive Immune Repertoires

Integrating high‐throughput screening and sequencing for monoclonal antibody discovery and engineering

Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development

A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim)

speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing

Immunogenomic engineering of a plug-and-(dis)play hybridoma platform

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

Tcf1 + cells are required to maintain the inflationary T cell pool upon MCMV infection

Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow

A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients

Aglycosylated IgG variants expressed in bacteria that selectively bind FcγRI potentiate tumor cell killing by monocyte-dendritic cells

Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

Tracing Antibody Repertoire Evolution by Systems Phylogeny

Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing

Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections

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