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Five computational developability guidelines for therapeutic antibody profiling

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4025-4030

2019

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Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies

PLoS computational biology, 2021-12, Vol.17 (12), p.e1009675-e1009675

2021

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Public Baseline and shared response structures support the theory of antibody repertoire functional commonality

PLoS computational biology, 2021-03, Vol.17 (3), p.e1008781-e1008781

2021

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Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice

PLoS computational biology, 2020-02, Vol.16 (2), p.e1007636-e1007636

2020

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SAbDab in the age of biotherapeutics: updates including SAbDab-nano, the nanobody structure tracker

Nucleic acids research, 2022-01, Vol.50 (D1), p.D1368-D1372

2022

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Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling

Communications biology, 2024-01, Vol.7 (1), p.62-62, Article 62

2024

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Thera-SAbDab: the Therapeutic Structural Antibody Database

Nucleic acids research, 2020-01, Vol.48 (D1), p.D383-D388

2020

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Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

Frontiers in immunology, 2020-12, Vol.11, p.605170-605170

2020

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The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures

Nucleic acids research, 2024-01, Vol.52 (D1), p.D545-D551

2024

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Prospects for the computational humanization of antibodies and nanobodies

Frontiers in immunology, 2024-05, Vol.15, p.1399438

2024

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Current strategies for detecting functional convergence across B-cell receptor repertoires

mAbs, 2021-01, Vol.13 (1), p.1996732-1996732

2021

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Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies

Frontiers in immunology, 2023-01, Vol.13, p.1080596-1080596

2023

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Looking for therapeutic antibodies in next-generation sequencing repositories

mAbs, 2019-10, Vol.11 (7), p.1197-1205

2019

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CoV-AbDab: the coronavirus antibody database

Bioinformatics, 2021-05, Vol.37 (5), p.734-735

2021

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Antibody-antigen complex modelling in the era of immunoglobulin repertoire sequencing

Molecular systems design & engineering, 2019-08, Vol.4 (4), p.679-688

2019

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Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope

Frontiers in molecular biosciences, 2023-09, Vol.10, p.1237621

2023

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Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (7), p.e2311049121-e2311049121

2024

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The Observed T Cell Receptor Space database enables paired-chain repertoire mining, coherence analysis, and language modeling

Cell reports (Cambridge), 2024-09, Vol.43 (9), p.114704, Article 114704

2024

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The Therapeutic Antibody Profiler for Computational Developability Assessment

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2313, p.115

2022

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A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs

mAbs, 2024-01, Vol.16 (1), p.2403156

2024

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Looking for therapeutic antibodies in next-generation sequencing repositories

mAbs, 2019, Vol.11 (7), p.1197-1205

2019

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Stabilisation of a progressive railway embankment slip

Geomechanics and geoengineering : an international journal, 2008-12, Vol.3 (4), p.257-270

2008

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Stabilisation of the Stanton Lees Landslip Using an Embedded Pile Retaining Wall

Geotechnical and geological engineering, 2007-12, Vol.25 (6), p.705-715

2007

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Key questions for next-generation of biomonitoring

A next-generation of biomonitoring to detect global ecosystem change. Frontiers Research Topics, 2020, p.91-104

2020

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Five computational developability guidelines for therapeutic antibody profiling

Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies

Public Baseline and shared response structures support the theory of antibody repertoire functional commonality

Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice

SAbDab in the age of biotherapeutics: updates including SAbDab-nano, the nanobody structure tracker

Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling

Thera-SAbDab: the Therapeutic Structural Antibody Database

Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures

The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures

Prospects for the computational humanization of antibodies and nanobodies

Current strategies for detecting functional convergence across B-cell receptor repertoires

Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies

Looking for therapeutic antibodies in next-generation sequencing repositories

CoV-AbDab: the coronavirus antibody database

Antibody-antigen complex modelling in the era of immunoglobulin repertoire sequencing

Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope

Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis

The Observed T Cell Receptor Space database enables paired-chain repertoire mining, coherence analysis, and language modeling

Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells

The Therapeutic Antibody Profiler for Computational Developability Assessment

A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs

Looking for therapeutic antibodies in next-generation sequencing repositories

Stabilisation of a progressive railway embankment slip

Stabilisation of the Stanton Lees Landslip Using an Embedded Pile Retaining Wall

Key questions for next-generation of biomonitoring

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