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Fragment library design, synthesis and expansion: nurturing a synthesis and training platform

Drug discovery today, 2017-01, Vol.22 (1), p.43-56

2017

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Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

Nature communications, 2021-01, Vol.12 (1), p.143-143, Article 143

2021

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Nitro-Mannich/Lactamization Cascades for the Direct Stereoselective Synthesis of Pyrrolidin-2-ones

Organic letters, 2009-10, Vol.11 (20), p.4512-4515

2009

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PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

Science (American Association for the Advancement of Science), 2020-03, Vol.367 (6482), p.1147-1151

2020

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Structure–Activity Relationships of Pyrazolo[1,5‑a]pyrimidin-7(4H)‑ones as Antitubercular Agents

ACS infectious diseases, 2021-02, Vol.7 (2), p.479-492

2021

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Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis

Antimicrobial agents and chemotherapy, 2014-11, Vol.58 (11), p.6962-6965

2014

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Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6592-6608

2018

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Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis

Cell chemical biology, 2021-08, Vol.28 (8), p.1180-1191.e20

2021

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Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis

Antimicrobial agents and chemotherapy, 2019-10, Vol.63 (10)

2019

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Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.719-740

2021

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Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis "

Antimicrobial agents and chemotherapy, 2017-09, Vol.61 (9)

2017

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Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA

ChemMedChem, 2018-04, Vol.13 (7), p.672-677

2018

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Diastereoselective Synthesis of 1,3,5-Trisubstituted 4-Nitropyrrolidin-2-ones via a Nitro-Mannich/Lactamization Cascade

Organic letters, 2011-12, Vol.13 (24), p.6406-6409

2011

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Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl‑l‑cysteine Synthetase (CoaB) Activity

ACS infectious diseases, 2021-06, Vol.7 (6), p.1666-1679

2021

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Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6027-6031

2009

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The role of phthiocerol dimycoserosate and the PE/PPE protein family in outer cell wall permeability in Mycobacterium tuberculosis

Science (American Association for the Advancement of Science), 2020-03, Vol.367 (6482), p.1147-1151

2020

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

ACS infectious diseases, 2017-01, Vol.3 (1), p.18-33

2017

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Liver X receptor agonists as a treatment for atherosclerosis

Expert opinion on therapeutic patents, 2004-07, Vol.14 (7), p.967-982

2004

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ChemInform Abstract: Diastereoselective Synthesis of 1,3,5-Trisubstituted 4-Nitropyrrolidin-2-ones via a Nitro-Mannich/Lactamization Cascade

ChemInform, 2012-04, Vol.43 (15), p.no-no

2012

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Juliá–Colonna stereoselective epoxidation of some α,β-unsaturated enones possessing a stereogenic centre at the γ-position: synthesis of a protected galactonic acid derivative

Perkin 1 : an international journal of organic and bio-organic chemistry, 2001-01 (2), p.149-153

2001

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ChemInform Abstract: Nitro-Mannich/Lactamization Cascades for the Direct Stereoselective Synthesis of Pyrrolidin-2-ones

ChemInform, 2010-03, Vol.41 (11), p.no-no

2010

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ChemInform Abstract: Julia-Colonna Stereoselective Epoxidation of Some α,β-Unsaturated Enones Possessing a Stereogenic Center at the γ-Position: Synthesis of a Protected Galactonic Acid Derivative

ChemInform, 2001-05, Vol.32 (18), p.no-no

2001

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Complementary roles of interventional radiology and therapeutic endoscopy in gastroenterology

World journal of radiology, 2017-03, Vol.9 (3), p.97-111

2017

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Fragment library design, synthesis and expansion: nurturing a synthesis and training platform

Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

Nitro-Mannich/Lactamization Cascades for the Direct Stereoselective Synthesis of Pyrrolidin-2-ones

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

Structure–Activity Relationships of Pyrazolo[1,5‑a]pyrimidin-7(4H)‑ones as Antitubercular Agents

Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis

Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis

Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies

2‑Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis "

Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA

Diastereoselective Synthesis of 1,3,5-Trisubstituted 4-Nitropyrrolidin-2-ones via a Nitro-Mannich/Lactamization Cascade

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl‑l‑cysteine Synthetase (CoaB) Activity

Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model

The role of phthiocerol dimycoserosate and the PE/PPE protein family in outer cell wall permeability in Mycobacterium tuberculosis

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

Liver X receptor agonists as a treatment for atherosclerosis

ChemInform Abstract: Diastereoselective Synthesis of 1,3,5-Trisubstituted 4-Nitropyrrolidin-2-ones via a Nitro-Mannich/Lactamization Cascade

Juliá–Colonna stereoselective epoxidation of some α,β-unsaturated enones possessing a stereogenic centre at the γ-position: synthesis of a protected galactonic acid derivative

ChemInform Abstract: Nitro-Mannich/Lactamization Cascades for the Direct Stereoselective Synthesis of Pyrrolidin-2-ones

ChemInform Abstract: Julia-Colonna Stereoselective Epoxidation of Some α,β-Unsaturated Enones Possessing a Stereogenic Center at the γ-Position: Synthesis of a Protected Galactonic Acid Derivative

Complementary roles of interventional radiology and therapeutic endoscopy in gastroenterology

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