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Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog

The Journal of pharmacology and experimental therapeutics, 2004-12, Vol.311 (3), p.1038

2004

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Unprecedented Acceleration of Zirconium(IV)-Assisted Peptide Hydrolysis at Neutral pH

Inorganic chemistry, 2004-10, Vol.43 (20), p.6130-6132

2004

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Methanocarba Modification of Uracil and Adenine Nucleotides: High Potency of Northern Ring Conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but Not P2Y6 Receptors

Journal of medicinal chemistry, 2002-01, Vol.45 (1), p.208-218

2002

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Quantitation of the P2Y1 Receptor with a High Affinity Radiolabeled Antagonist

Molecular pharmacology, 2002-11, Vol.62 (5), p.1249-1257

2002

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Methanocarba Analogues of Purine Nucleosides as Potent and Selective Adenosine Receptor Agonists

Journal of medicinal chemistry, 2000-06, Vol.43 (11), p.2196-2203

2000

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Adenine Nucleotide Analogues Locked in a Northern Methanocarba Conformation: Enhanced Stability and Potency as P2Y1 Receptor Agonists

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2090-2100

2002

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2‐Chloro N6‐methyl‐(N)‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate is a selective high affinity P2Y1 receptor antagonist

British journal of pharmacology, 2002-04, Vol.135 (8), p.2004-2010

2002

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Potent P2X7 receptor antagonists: Tyrosyl derivatives synthesized using a sequential parallel synthetic approach

Drug development research, 2001-10, Vol.54 (2), p.75-87

2001

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Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

Molecular pharmacology, 2002-11, Vol.62 (5), p.1249-1257

2002

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p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA

Biochemical pharmacology, 2002-03, Vol.63 (5), p.871-880

2002

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Ring-Constrained (N)-Methanocarba nucleosides as adenosine receptor agonists: independent 5′-Uronamide and 2′-deoxy modifications

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (10), p.1333-1337

2001

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2‐Chloro N 6 ‐methyl‐(N)‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate is a selective high affinity P2Y 1 receptor antagonist

British journal of pharmacology, 2009-02, Vol.135 (8), p.2004-2010

2009

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Potent P2X 7 Receptor Antagonists: Tyrosyl Derivatives Synthesized Using a Sequential Parallel Synthetic Approach

Drug development research, 2001-10, Vol.54 (2), p.75-87

2001

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Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2090-2100

2002

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Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2295-2300

2001

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Quantitation of the P2Y 1 Receptor with a High Affinity Radiolabeled Antagonist

Molecular pharmacology, 2002-11, Vol.62 (5), p.1249-1257

2002

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Functionalized Congeners of Tyrosine-Based P2X7 Receptor Antagonists: Probing Multiple Sites for Linking and Dimerization

Bioconjugate chemistry, 2002-09, Vol.13 (5), p.1100-1111

2002

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Stereodivergent Approach to α-Hydroxy Acids Involving Substrate Directed Reduction of α-Keto Amides

Tetrahedron letters, 1995-08, Vol.36 (33), p.5959-5962

Pansare, S

1995

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Engineering of A 3 adenosine and P2Y nucleotide receptors and their ligands

Drug development research, 2003-04, Vol.58 (4), p.330-339

2003

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Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarbapseudoribose rings

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (17), p.2295-2300

2001

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Induction of Novel Agonist Selectivity for the ADP-Activated P2Y 1 Receptor Versus the ADP-Activated P2Y 12 and P2Y 13 Receptors by Conformational Constraint of an ADP Analog

The Journal of pharmacology and experimental therapeutics, 2004-12, Vol.311 (3), p.1038-1043

2004

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Stereodivergent approach to α-hydroxy acids involving substrate directed reduction of α-keto amides

Tetrahedron letters, 1995-08, Vol.36 (33), p.5959-5962

1995

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Engineering of A3 adenosine and P2Y nucleotide receptors and their ligands

Drug development research, 2003-04, Vol.58 (4), p.330-339

2003

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Asymmetric Allylation and Reduction on an Ephedrine-Derived Template: Stereoselective Synthesis of α-Hydroxy Acids and Derivatives

Journal of organic chemistry, 1998-06, Vol.63 (12), p.4120-4124

1998

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Asymmetric reactions of α-ketoacid-derived hemiacetals: Stereoselective synthesis of α-hydroxy acids

Tetrahedron, 1998-11, Vol.54 (48), p.14549-14564

1998

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Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog

Unprecedented Acceleration of Zirconium(IV)-Assisted Peptide Hydrolysis at Neutral pH

Methanocarba Modification of Uracil and Adenine Nucleotides: High Potency of Northern Ring Conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but Not P2Y6 Receptors

Quantitation of the P2Y1 Receptor with a High Affinity Radiolabeled Antagonist

Methanocarba Analogues of Purine Nucleosides as Potent and Selective Adenosine Receptor Agonists

Adenine Nucleotide Analogues Locked in a Northern Methanocarba Conformation: Enhanced Stability and Potency as P2Y1 Receptor Agonists

2‐Chloro N6‐methyl‐(N)‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate is a selective high affinity P2Y1 receptor antagonist

Potent P2X7 receptor antagonists: Tyrosyl derivatives synthesized using a sequential parallel synthetic approach

Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

p53-Independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, Cl-IB-MECA

Ring-Constrained (N)-Methanocarba nucleosides as adenosine receptor agonists: independent 5′-Uronamide and 2′-deoxy modifications

2‐Chloro N 6 ‐methyl‐(N)‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate is a selective high affinity P2Y 1 receptor antagonist

Potent P2X 7 Receptor Antagonists: Tyrosyl Derivatives Synthesized Using a Sequential Parallel Synthetic Approach

Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists

Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings

Quantitation of the P2Y 1 Receptor with a High Affinity Radiolabeled Antagonist

Functionalized Congeners of Tyrosine-Based P2X7 Receptor Antagonists: Probing Multiple Sites for Linking and Dimerization

Stereodivergent Approach to α-Hydroxy Acids Involving Substrate Directed Reduction of α-Keto Amides

Engineering of A 3 adenosine and P2Y nucleotide receptors and their ligands

Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarbapseudoribose rings

Induction of Novel Agonist Selectivity for the ADP-Activated P2Y 1 Receptor Versus the ADP-Activated P2Y 12 and P2Y 13 Receptors by Conformational Constraint of an ADP Analog

Stereodivergent approach to α-hydroxy acids involving substrate directed reduction of α-keto amides

Engineering of A3 adenosine and P2Y nucleotide receptors and their ligands

Asymmetric Allylation and Reduction on an Ephedrine-Derived Template: Stereoselective Synthesis of α-Hydroxy Acids and Derivatives

Asymmetric reactions of α-ketoacid-derived hemiacetals: Stereoselective synthesis of α-hydroxy acids

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