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Bioreductive therapies: an overview of drugs and their mechanisms of action

International journal of radiation oncology, biology, physics, 1998-11, Vol.42 (4), p.755-762

1998

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Assessment of the relationship between genotypic status of a DT-diaphorase point mutation and enzymatic activity

British journal of cancer, 2000-10, Vol.83 (8), p.998-1002

2000

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Presence of a heterozygous substitution and its relationship to DT-diaphorase activity

British journal of cancer, 1995-09, Vol.72 (3), p.555-561

1995

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Cellular accumulation and retention of the technetium-99m-labelled hypoxia markers BRU59-21 and butylene amine oxime

Nuclear medicine and biology, 2001-11, Vol.28 (8), p.949-957

2001

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Biodegradable dextran-based microspheres for delivery of anticancer drug mitomycin C

Biomaterials, 2005-09, Vol.26 (26), p.5375-5385

2005

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Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models

Nuclear medicine communications, 2003-05, Vol.24 (5), p.597-606

2003

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Targeting Hypoxia in Tumors Using 2-Nitroimidazoles with Peptidic Chelators for Technetium-99m: Effect of Lipophilicity

Bioconjugate chemistry, 2000-05, Vol.11 (3), p.401-407

2000

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A Novel Amine−Dioxime Chelator for Technetium-99m: Synthesis and Evaluation of 2-Nitroimidazole-Containing Analogues as Markers for Hypoxic Cells

Bioconjugate chemistry, 2000-09, Vol.11 (5), p.652-663

2000

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Principles and applications of ultrasound backscatter microscopy

IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 1993-09, Vol.40 (5), p.608-617

1993

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Mechanism of ultrasound enhanced porphyrin cytotoxicity. Part I: A search for free radical effects

Ultrasound in medicine & biology, 1997, Vol.23 (7), p.1095-1105

1997

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DT-diaphorase: possible roles in cancer chemotherapy and carcinogenesis

Oncology research, 1997, Vol.9 (6-7), p.339

1997

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A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres

Journal of controlled release, 2001-12, Vol.77 (3), p.213-224

2001

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Role of NADPH:cytochrome P450 reductase in the hypoxic accumulation and metabolism of BRU59-21, a technetium-99m-nitroimidazole for imaging tumor hypoxia

Biochemical pharmacology, 2000-09, Vol.60 (5), p.625-634

2000

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Synthesis and Evaluation of Two Technetium-99m-Labeled Peptidic 2-Nitroimidazoles for Imaging Hypoxia

Bioconjugate chemistry, 1999-09, Vol.10 (5), p.897-904

1999

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A polymorphism in NAD(P)H:quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity

British journal of cancer, 1996-09, Vol.74 (6), p.995-996

1996

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Transfection of COS-1 cells with DT-diaphorase cDNA: role of a base change at position 609

British journal of cancer, 1998-04, Vol.77 (8), p.1236-1240

1998

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Expression of the prodrug-activating enzyme DT-diaphorase via Ad5 delivery to human colon carcinoma cells in vitro

Cancer gene therapy, 2002-02, Vol.9 (2), p.209-217

2002

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Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells

British journal of cancer, 1997, Vol.76 (2), p.180-188

1997

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Differential cell death in immortalized and non-immortalized cells at confluency

Oncogene, 1996-01, Vol.12 (1), p.201-206

1996

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Oxidative Stress and 1-Methyl-2-nitroimidazole Cytotoxicity

Biochemical pharmacology, 1998-08, Vol.56 (3), p.335-344

1998

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Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions

British journal of cancer, 1989-03, Vol.59 (3), p.341-346

1989

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A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres

Journal of controlled release, 2004-11, Vol.100 (1), p.121-133

2004

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Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres

Journal of pharmacy and pharmacology, 2003-08, Vol.55 (8), p.1063-1073

2003

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5-fluorouracil infusions and fractionated doses of radiation: Studies with a murine squamous cell carcinoma

International journal of radiation oncology, biology, physics, 1987-11, Vol.13 (11), p.1691-1699

1987

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Mode of interaction of 5-fluorouracil, radiation, and mitomycin C: In vitro studies

International journal of radiation oncology, biology, physics, 1992, Vol.22 (5), p.875-880

1992

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Bioreductive therapies: an overview of drugs and their mechanisms of action

Assessment of the relationship between genotypic status of a DT-diaphorase point mutation and enzymatic activity

Presence of a heterozygous substitution and its relationship to DT-diaphorase activity

Cellular accumulation and retention of the technetium-99m-labelled hypoxia markers BRU59-21 and butylene amine oxime

Biodegradable dextran-based microspheres for delivery of anticancer drug mitomycin C

Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models

Targeting Hypoxia in Tumors Using 2-Nitroimidazoles with Peptidic Chelators for Technetium-99m: Effect of Lipophilicity

A Novel Amine−Dioxime Chelator for Technetium-99m: Synthesis and Evaluation of 2-Nitroimidazole-Containing Analogues as Markers for Hypoxic Cells

Principles and applications of ultrasound backscatter microscopy

Mechanism of ultrasound enhanced porphyrin cytotoxicity. Part I: A search for free radical effects

DT-diaphorase: possible roles in cancer chemotherapy and carcinogenesis

A study of doxorubicin loading onto and release from sulfopropyl dextran ion-exchange microspheres

Role of NADPH:cytochrome P450 reductase in the hypoxic accumulation and metabolism of BRU59-21, a technetium-99m-nitroimidazole for imaging tumor hypoxia

Synthesis and Evaluation of Two Technetium-99m-Labeled Peptidic 2-Nitroimidazoles for Imaging Hypoxia

A polymorphism in NAD(P)H:quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity

Transfection of COS-1 cells with DT-diaphorase cDNA: role of a base change at position 609

Expression of the prodrug-activating enzyme DT-diaphorase via Ad5 delivery to human colon carcinoma cells in vitro

Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells

Differential cell death in immortalized and non-immortalized cells at confluency

Oxidative Stress and 1-Methyl-2-nitroimidazole Cytotoxicity

Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditions

A new approach to the in vivo and in vitro investigation of drug release from locoregionally delivered microspheres

Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres

5-fluorouracil infusions and fractionated doses of radiation: Studies with a murine squamous cell carcinoma

Mode of interaction of 5-fluorouracil, radiation, and mitomycin C: In vitro studies

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