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Analytic framework for peptidomics applied to large-scale neuropeptide identification

Nature communications, 2016-05, Vol.7 (1), p.11436-11436, Article 11436

2016

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Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

PloS one, 2022-03, Vol.17 (3), p.e0264974-e0264974

2022

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Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.101-110

2014

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The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs

Scientific reports, 2021-10, Vol.11 (1), p.21179-21179, Article 21179

2021

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FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation

Endocrine Connections, 2020-08, Vol.9 (8), p.755-768

2020

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Liraglutide, a Long-Acting Glucagon-Like Peptide-1 Analog, Reduces Body Weight and Food Intake in Obese Candy-Fed Rats, Whereas a Dipeptidyl Peptidase-IV Inhibitor, Vildagliptin, Does Not

Diabetes (New York, N.Y.), 2007-01, Vol.56 (1), p.8-15

2007

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Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114501-114501, Article 114501

2024

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Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

PloS one, 2016-01, Vol.11 (1), p.e0147412-e0147412

2016

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Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

Current diabetes reviews, 2016-12, Vol.12 (4), p.331-358

2016

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Liraglutide, a Once-daily Human Glucagon-like Peptide-1 Analog, Minimizes Food Intake in Severely Obese Minipigs

Obesity (Silver Spring, Md.), 2007-07, Vol.15 (7), p.1710-1716

2007

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Improved leptin sensitivity and increased soluble leptin receptor concentrations may underlie the additive effects of combining PYY [1–34] and exendin-4 on body weight lowering in diet-induced obese mice

Heliyon, 2024-06, Vol.10 (12), p.e32009, Article e32009

2024

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Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats

Diabetes (New York, N.Y.), 2010-10, Vol.59 (10), p.2653-2661

2010

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Influence of castration-induced testosterone and estradiol deficiency on obesity and glucose metabolism in male Göttingen minipigs

Steroids, 2010-10, Vol.75 (10), p.676-684

2010

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α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK

PloS one, 2016-07, Vol.11 (7), p.e0157027-e0157027

2016

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Growth hormone treatment does not augment the anti‐diabetic effects of liraglutide in UCD‐T2DM rats

Endocrinology, diabetes & metabolism, 2023-01, Vol.6 (1), p.e392-n/a

2023

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Preclinical Evaluation of FGF21 or Liraglutide in Combination with a Long-Acting DACRA in DIO Mice

Obesity (Silver Spring, Md.), 2021-12, Vol.29, p.144-144

2021

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Preclinical Efficacy of NN1213, an Amylin Receptor Selective Analogue, in Animal Models of Obesity

Obesity (Silver Spring, Md.), 2021-12, Vol.29, p.144-144

2021

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Translational Mapping and Profiling of Neuronal Populations Targeted by Amylin and GLP-1

Obesity (Silver Spring, Md.), 2022-11, Vol.30, p.124-125

2022

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Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss

Obesity (Silver Spring, Md.), 2022-04, Vol.30 (4), p.841-857

2022

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The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

The Journal of clinical investigation, 2014-10, Vol.124 (10), p.4473-4488

2014

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CagriSema Attenuates Metabolic Adaptation Associated With Weight Loss in Diet-Induced Obese Rats

Obesity (Silver Spring, Md.), 2022-11, Vol.30, p.132-132

2022

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Development of Cagrilintide, a Long-Acting Amylin Analogue

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11183-11194

2021

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Effects of a selective long‐acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats

Addiction biology, 2021-03, Vol.26 (2), p.e12910-n/a

2021

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Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

Neuropharmacology, 2020-05, Vol.167, p.107987-107987, Article 107987

2020

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Semaglutide lowers body weight in rodents via distributed neural pathways

Analytic framework for peptidomics applied to large-scale neuropeptide identification

Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice

The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs

FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation

Liraglutide, a Long-Acting Glucagon-Like Peptide-1 Analog, Reduces Body Weight and Food Intake in Obese Candy-Fed Rats, Whereas a Dipeptidyl Peptidase-IV Inhibitor, Vildagliptin, Does Not

Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans

Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

Liraglutide, a Once-daily Human Glucagon-like Peptide-1 Analog, Minimizes Food Intake in Severely Obese Minipigs

Improved leptin sensitivity and increased soluble leptin receptor concentrations may underlie the additive effects of combining PYY [1–34] and exendin-4 on body weight lowering in diet-induced obese mice

Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats

Influence of castration-induced testosterone and estradiol deficiency on obesity and glucose metabolism in male Göttingen minipigs

α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK

Growth hormone treatment does not augment the anti‐diabetic effects of liraglutide in UCD‐T2DM rats

Preclinical Evaluation of FGF21 or Liraglutide in Combination with a Long-Acting DACRA in DIO Mice

Preclinical Efficacy of NN1213, an Amylin Receptor Selective Analogue, in Animal Models of Obesity

Translational Mapping and Profiling of Neuronal Populations Targeted by Amylin and GLP-1

Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

CagriSema Attenuates Metabolic Adaptation Associated With Weight Loss in Diet-Induced Obese Rats

Development of Cagrilintide, a Long-Acting Amylin Analogue

Effects of a selective long‐acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats

Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

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