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P-Glycoprotein Recognition of Substrates and Circumvention through Rational Drug Design

Molecular pharmaceutics, 2006-01, Vol.3 (1), p.3-25

Raub, Thomas J

2006

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Integration of in Silico and in Vitro Tools for Scaffold Optimization during Drug Discovery: Predicting P‑Glycoprotein Efflux

Molecular pharmaceutics, 2013-04, Vol.10 (4), p.1249-1261

2013

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In Silico and in Vitro Assessment of OATP1B1 Inhibition in Drug Discovery

Molecular pharmaceutics, 2018-08, Vol.15 (8), p.3060-3068

2018

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Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial

Nutrients, 2018-11, Vol.10 (11), p.1807

2018

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Carbon monoxide poisoning — a public health perspective

Toxicology, 2000-04, Vol.145 (1), p.1-14

2000

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Carbon monoxide and the nervous system

Neuroscience and Biobehavioral Reviews, 2002-12, Vol.26 (8), p.925-940

2002

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QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain: Incorporating P-glycoprotein Efflux as a Variable

Journal of chemical information and modeling, 2016-11, Vol.56 (11), p.2225-2233

2016

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In vitro models for the blood–brain barrier

Toxicology in vitro, 2005-04, Vol.19 (3), p.299-334

2005

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The Important Role of Bcrp (Abcg2) in the Biliary Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Mice

Molecular pharmacology, 2006-12, Vol.70 (6), p.2127-2133

2006

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Predictors and outcomes in primary depression care (POKAL) - a research training group develops an innovative approach to collaborative care

BMC primary care, 2022-12, Vol.23 (1), p.309-309, Article 309

2022

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Breast cancer resistance protein interacts with various compounds in vitro, but plays a minor role in substrate efflux at the blood-brain barrier

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1251

2009

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Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft

Drug metabolism and disposition, 2015-09, Vol.43 (9), p.1360-1371

2015

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How hydrogen bonds impact P-glycoprotein transport and permeability

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6540-6548

2012

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Rhodamine Inhibitors of P-Glycoprotein: An Amide/Thioamide “Switch” for ATPase Activity

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3328-3341

2009

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Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

Gastroenterology (New York, N.Y. 1943), 1989-03, Vol.96 (3), p.736-749

1989

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Determination of the Affinity of Drugs toward Serum Albumin by Measurement of the Quenching of the Intrinsic Tryptophan Fluorescence of the Protein

Journal of pharmacy and pharmacology, 1999-01, Vol.51 (1), p.41-48

1999

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Efficiency Gains in Tracer Identification for Nuclear Imaging: Can In Vivo LC-MS/MS Evaluation of Small Molecules Screen for Successful PET Tracers?

ACS chemical neuroscience, 2014-12, Vol.5 (12), p.1154-1163

2014

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Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice

Drug metabolism and disposition, 2008-01, Vol.36 (1), p.61

2008

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Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1916

2009

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Pharmacokinetics of a 80mg Sublingual Dose of Delta‐Tocotrienol Powder

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Pharmacokinetics of a 40mg Sublingual Dose of Delta‐Tocotrienol Powder

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Quantitative Approaches To Delineate Paracellular Diffusion in Cultured Epithelial Cell Monolayers

Journal of pharmaceutical sciences, 1994-11, Vol.83 (11), p.1529-1536

1994

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Roles of P-Glycoprotein, Bcrp, and Mrp2 in Biliary Excretion of Spiramycin in Mice

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3230-3234

2007

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Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.718

2006

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Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions

American Journal of Physiology: Cell Physiology, 1996-08, Vol.271 (2), p.C495-C503

Raub, T. J

1996

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P-Glycoprotein Recognition of Substrates and Circumvention through Rational Drug Design

Integration of in Silico and in Vitro Tools for Scaffold Optimization during Drug Discovery: Predicting P‑Glycoprotein Efflux

In Silico and in Vitro Assessment of OATP1B1 Inhibition in Drug Discovery

Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial

Carbon monoxide poisoning — a public health perspective

Carbon monoxide and the nervous system

QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain: Incorporating P-glycoprotein Efflux as a Variable

In vitro models for the blood–brain barrier

The Important Role of Bcrp (Abcg2) in the Biliary Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Mice

Predictors and outcomes in primary depression care (POKAL) - a research training group develops an innovative approach to collaborative care

Breast cancer resistance protein interacts with various compounds in vitro, but plays a minor role in substrate efflux at the blood-brain barrier

Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft

How hydrogen bonds impact P-glycoprotein transport and permeability

Rhodamine Inhibitors of P-Glycoprotein: An Amide/Thioamide “Switch” for ATPase Activity

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

Determination of the Affinity of Drugs toward Serum Albumin by Measurement of the Quenching of the Intrinsic Tryptophan Fluorescence of the Protein

Efficiency Gains in Tracer Identification for Nuclear Imaging: Can In Vivo LC-MS/MS Evaluation of Small Molecules Screen for Successful PET Tracers?

Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice

Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver

Pharmacokinetics of a 80mg Sublingual Dose of Delta‐Tocotrienol Powder

Pharmacokinetics of a 40mg Sublingual Dose of Delta‐Tocotrienol Powder

Quantitative Approaches To Delineate Paracellular Diffusion in Cultured Epithelial Cell Monolayers

Roles of P-Glycoprotein, Bcrp, and Mrp2 in Biliary Excretion of Spiramycin in Mice

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions

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