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Process development in Quality‐by‐Design paradigm for anti‐solvent aided crystallization: impact of crystallization parameters on particle morphology and dissolution behaviour of Dexlansoprazole active pharmaceutical ingredient

Journal of chemical technology and biotechnology (1986), 2024-08, Vol.99 (8), p.1734-1742

2024

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Application of PAT in pharmaceutical manufacturing: model‐based control of particle size distribution in anti‐solvent aided crystallization

Journal of chemical technology and biotechnology (1986), 2023-12, Vol.98 (12), p.2806-2811

2023

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Electron microscopy-based semi-automated characterization of aggregation in monoclonal antibody products

Computational and structural biotechnology journal, 2020-01, Vol.18, p.1458-1465

2020

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Quality by design for biopharmaceuticals: principles and case studies

1st ed., 2009

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Process optimization using machine learning enhanced design of experiments (DOE): ranibizumab refolding as a case study

Reaction chemistry & engineering, 2023-02, Vol.8 (3), p.592-603

2023

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Digitization in bioprocessing: The role of soft sensors in monitoring and control of downstream processing for production of biotherapeutic products

Biosensors and bioelectronics. X, 2022-12, Vol.12, p.100263, Article 100263

2022

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Improved Stability and Manufacturability of Nucleocapsid Antigens for SARS-CoV2 Diagnostics through Protein Engineering

Biomolecules (Basel, Switzerland), 2023-10, Vol.13 (10), p.1524

2023

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Preparative Chromatography for Separation of Proteins

1, 2017

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Profiling Enzyme Activity of l‑Asparaginase II by NMR-Based Methyl Fingerprinting at Natural Abundance

Journal of the American Chemical Society, 2023-05, Vol.145 (19), p.10826-10838

2023

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Multi-Level High-Throughput Screening for Discovery of Ligands That Inhibit Insulin Aggregation

Molecular pharmaceutics, 2022-11, Vol.19 (11), p.3770-3783

2022

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Front Cover: A simple, rapid, and robust “on‐the‐go” identity testing of biotherapeutics using FTIR spectroscopy

Electrophoresis, 2021-08, Vol.42 (16), p.NA

2021

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Equilibrium Ensembles for Insulin Folding from Bias-Exchange Metadynamics

Biophysical journal, 2017-04, Vol.112 (8), p.1571-1585

2017

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A simple, rapid, and robust “on‐the‐go” identity testing of biotherapeutics using FTIR spectroscopy

Electrophoresis, 2021-08, Vol.42 (16), p.1655-1664

2021

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Analysis for residual host cell proteins and DNA in process streams of a recombinant protein product expressed in Escherichia coli cells

Journal of pharmaceutical and biomedical analysis, 2003-08, Vol.32 (6), p.1199-1211

2003

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Differential migration processes in analytical separation: Capillary zone electrophoresis and electrochromatography

Rathore, Anurag Singh

1999

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Requirements for validating a capillary isoelectric focusing method for impurity quantitation

LC GC North America, 2002-11, Vol.20 (11), p.1042-1050

2002

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Biomass to fuels and chemicals: A review of enabling processes and technologies

Journal of chemical technology and biotechnology (1986), 2022-03, Vol.97 (3), p.597-607

2022

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LC-MS based case-by-case analysis of the impact of acidic and basic charge variants of bevacizumab on stability and biological activity

Scientific reports, 2021-01, Vol.11 (1), p.2487-2487, Article 2487

2021

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Structure-Based Design of Small Peptide Ligands to Inhibit Early-Stage Protein Aggregation Nucleation

Journal of chemical information and modeling, 2020-06, Vol.60 (6), p.3304-3314

2020

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Should charge variants of monoclonal antibody therapeutics be considered critical quality attributes?

Electrophoresis, 2016-09, Vol.37 (17-18), p.2338-2346

2016

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Understanding the mechanism of copurification of “difficult to remove” host cell proteins in rituximab biosimilar products

Biotechnology progress, 2020-03, Vol.36 (2), p.e2936-n/a

2020

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Assessment of Functional Characterization and Comparability of Biotherapeutics: a Review

The AAPS journal, 2021-12, Vol.24 (1), p.15-15, Article 15

2021

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A Charge Variant of Bevacizumab Offers Enhanced FcRn-Dependent Pharmacokinetic Half-Life and Efficacy

Pharmaceutical research, 2022-05, Vol.39 (5), p.851-865

2022

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Modulation of granulocyte colony stimulating factor conformation and receptor binding by methionine oxidation

Proteins, structure, function, and bioinformatics, 2021-01, Vol.89 (1), p.68-80

2021

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Understanding Oxidation Propensity in GCSF and Assessment of its Safety and Efficacy

Pharmaceutical research, 2020-10, Vol.37 (10), p.207-207, Article 207

2020

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Process development in Quality‐by‐Design paradigm for anti‐solvent aided crystallization: impact of crystallization parameters on particle morphology and dissolution behaviour of Dexlansoprazole active pharmaceutical ingredient

Application of PAT in pharmaceutical manufacturing: model‐based control of particle size distribution in anti‐solvent aided crystallization

Electron microscopy-based semi-automated characterization of aggregation in monoclonal antibody products

Quality by design for biopharmaceuticals: principles and case studies

Process optimization using machine learning enhanced design of experiments (DOE): ranibizumab refolding as a case study

Digitization in bioprocessing: The role of soft sensors in monitoring and control of downstream processing for production of biotherapeutic products

Improved Stability and Manufacturability of Nucleocapsid Antigens for SARS-CoV2 Diagnostics through Protein Engineering

Preparative Chromatography for Separation of Proteins

Profiling Enzyme Activity of l‑Asparaginase II by NMR-Based Methyl Fingerprinting at Natural Abundance

Multi-Level High-Throughput Screening for Discovery of Ligands That Inhibit Insulin Aggregation

Front Cover: A simple, rapid, and robust “on‐the‐go” identity testing of biotherapeutics using FTIR spectroscopy

Equilibrium Ensembles for Insulin Folding from Bias-Exchange Metadynamics

A simple, rapid, and robust “on‐the‐go” identity testing of biotherapeutics using FTIR spectroscopy

Analysis for residual host cell proteins and DNA in process streams of a recombinant protein product expressed in Escherichia coli cells

Differential migration processes in analytical separation: Capillary zone electrophoresis and electrochromatography

Requirements for validating a capillary isoelectric focusing method for impurity quantitation

Biomass to fuels and chemicals: A review of enabling processes and technologies

LC-MS based case-by-case analysis of the impact of acidic and basic charge variants of bevacizumab on stability and biological activity

Structure-Based Design of Small Peptide Ligands to Inhibit Early-Stage Protein Aggregation Nucleation

Should charge variants of monoclonal antibody therapeutics be considered critical quality attributes?

Understanding the mechanism of copurification of “difficult to remove” host cell proteins in rituximab biosimilar products

Assessment of Functional Characterization and Comparability of Biotherapeutics: a Review

A Charge Variant of Bevacizumab Offers Enhanced FcRn-Dependent Pharmacokinetic Half-Life and Efficacy

Modulation of granulocyte colony stimulating factor conformation and receptor binding by methionine oxidation

Understanding Oxidation Propensity in GCSF and Assessment of its Safety and Efficacy

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