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Innate immunity to intracellular LPS

Nature immunology, 2019-05, Vol.20 (5), p.527

2019

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AIM2 in health and disease: Inflammasome and beyond

Immunological reviews, 2020-09, Vol.297 (1), p.83-95

2020

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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Immunity (Cambridge, Mass.), 2012-04, Vol.36 (4), p.561-571

2012

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Citrobacter rodentium: infection, inflammation and the microbiota

Nature reviews. Microbiology, 2014-09, Vol.12 (9), p.612-623

2014

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Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

Cell, 2016-05, Vol.165 (5), p.1106-1119

2016

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TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Cell, 2012-08, Vol.150 (3), p.606-619

2012

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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

Immunity (Cambridge, Mass.), 2018-09, Vol.49 (3), p.413-426.e5

2018

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Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.7765-7770

2014

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Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

The Journal of immunology (1950), 2013-05, Vol.190 (10), p.5216-5225

2013

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A TLR4-independent critical role for CD14 in intracellular LPS sensing

Cell reports (Cambridge), 2022-05, Vol.39 (5), p.110755-110755, Article 110755

2022

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The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Nature immunology, 2010-05, Vol.11 (5), p.395

2010

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Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

The Journal of immunology (1950), 2012-12, Vol.189 (12), p.5508-5512

2012

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Inflammasome Complexes: Emerging Mechanisms and Effector Functions

Cell, 2016-05, Vol.165 (4), p.792-800

2016

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Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

Cell reports (Cambridge), 2021-04, Vol.35 (3), p.109012-109012, Article 109012

2021

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Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Nature immunology, 2013-06, Vol.14 (6), p.543

2013

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Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production

Immunity (Cambridge, Mass.), 2019-01, Vol.50 (1), p.51-63.e5

2019

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A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3

Nature communications, 2023-04, Vol.14 (1), p.2035-2035, Article 2035

2023

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Mechanisms of inflammasome activation: recent advances and novel insights

Trends in cell biology, 2015-05, Vol.25 (5), p.308-315

2015

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A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114004-114004, Article 114004

2024

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Innate immune sensing of DNA viruses

Virology (New York, N.Y.), 2011-03, Vol.411 (2), p.153-162

2011

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CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsis

Cell reports (Cambridge), 2023-03, Vol.42 (3), p.112171-112171, Article 112171

2023

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Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans

The Journal of immunology (1950), 2014-09, Vol.193 (5), p.2519-2530

2014

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Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system

The Journal of immunology (1950), 2013-10, Vol.191 (7), p.3514-3518

2013

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Regulation of inflammasome signaling

Nature immunology, 2012-04, Vol.13 (4), p.333

2012

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Inflammasome, Inflammation, and Tissue Homeostasis

Trends in molecular medicine, 2018-03, Vol.24 (3), p.304-318

2018

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Innate immunity to intracellular LPS

AIM2 in health and disease: Inflammasome and beyond

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Citrobacter rodentium: infection, inflammation and the microbiota

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

A TLR4-independent critical role for CD14 in intracellular LPS sensing

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production

A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3

Mechanisms of inflammasome activation: recent advances and novel insights

A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

Innate immune sensing of DNA viruses

CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsis

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans

Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system

Regulation of inflammasome signaling

Inflammasome, Inflammation, and Tissue Homeostasis

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