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Efficient synthesis of 5-alkyl amino and thioether substituted pyrazoles

Tetrahedron letters, 2003-10, Vol.44 (41), p.7629-7632

2003

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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.288-292

2006

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Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine

Bioorganic & medicinal chemistry letters, 2004-01, Vol.14 (1), p.95-98

2004

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Non-oxime inhibitors of B-Raf(V600E) kinase

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1243-1247

2011

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The Discovery of furo[2,3- c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1248-1252

2011

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Facile microwave assisted decarbonylation of 4-formyl group in 5-alkyl amino substituted pyrazoles

Tetrahedron letters, 2008-03, Vol.49 (14), p.2280-2282

2008

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Efficient fluoride-mediated synthesis of 5-alkyl amino- and ether-substituted pyrazoles

Tetrahedron letters, 2005-10, Vol.46 (40), p.6887-6891

2005

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Non-oxime inhibitors of B-Raf super(V600E) kinase

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1243-1247

2011

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Abstract 551: A potent and selective cFMS inhibitor regulates the tumor macrophage microenvironment leading to tumor growth inhibition

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.551-551

2011

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Non-oxime inhibitors of B-Raf V600E kinase

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (4), p.1243-1247

2011

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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: Molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.1067-1072

2007

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Non-oxime inhibitors of B-Rafⱽ⁶⁰⁰ᴱ kinase

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1243-1247

2011

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5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethers

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1202-1206

2006

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Comparative structure–activity relationship studies of 1-(5-methylsulfonylpyrid-2-yl)-5-alkyl and (hetero)aryl triazoles and pyrazoles in canine COX inhibition

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1042-1045

2008

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Efficient Synthesis of 5-Alkyl Amino and Thioether Substituted Pyrazoles

ChemInform, 2004-01, Vol.35 (2), p.no-no

2004

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ChemInform Abstract: Facile Microwave-Assisted Decarbonylation of 4-Formyl Group in 5-Alkylamino- Substituted Pyrazoles

ChemInform, 2008-07, Vol.39 (29), p.no-no

2008

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Efficient Fluoride-Mediated Synthesis of 5-Alkyl Amino- and Ether-Substituted Pyrazoles

ChemInform, 2006-01, Vol.37 (3), p.no-no

2006

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Efficient synthesis of 5-alkyl amino and thioether substituted pyrazoles

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine

Non-oxime inhibitors of B-Raf(V600E) kinase

The Discovery of furo[2,3- c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

Facile microwave assisted decarbonylation of 4-formyl group in 5-alkyl amino substituted pyrazoles

Efficient fluoride-mediated synthesis of 5-alkyl amino- and ether-substituted pyrazoles

Non-oxime inhibitors of B-Raf super(V600E) kinase

Abstract 551: A potent and selective cFMS inhibitor regulates the tumor macrophage microenvironment leading to tumor growth inhibition

Non-oxime inhibitors of B-Raf V600E kinase

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: Molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile

Non-oxime inhibitors of B-Rafⱽ⁶⁰⁰ᴱ kinase

5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethers

Comparative structure–activity relationship studies of 1-(5-methylsulfonylpyrid-2-yl)-5-alkyl and (hetero)aryl triazoles and pyrazoles in canine COX inhibition

Efficient Synthesis of 5-Alkyl Amino and Thioether Substituted Pyrazoles

ChemInform Abstract: Facile Microwave-Assisted Decarbonylation of 4-Formyl Group in 5-Alkylamino- Substituted Pyrazoles

Efficient Fluoride-Mediated Synthesis of 5-Alkyl Amino- and Ether-Substituted Pyrazoles

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