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Mitochondrial permeability transition in Ca2+ -dependent apoptosis and necrosis

Cell calcium (Edinburgh), 2011-09, Vol.50 (3), p.222-233

2011

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The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

Physiological reviews, 2015-10, Vol.95 (4), p.1111-1155

2015

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Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4716

2021

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Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase

Nature communications, 2021-08, Vol.12 (1), p.4835-4835, Article 4835

2021

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mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

Apoptosis (London), 2007-05, Vol.12 (5), p.815-833

2007

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The mitochondrial permeability transition pore and its adaptive responses in tumor cells

Cell calcium (Edinburgh), 2014-12, Vol.56 (6), p.437-445

2014

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The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells

Frontiers in oncology, 2017-03, Vol.7, p.58-58

2017

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Metabolic Plasticity of Tumor Cell Mitochondria

Frontiers in oncology, 2018-08, Vol.8, p.333-333

2018

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Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1

Cell reports (Cambridge), 2020-04, Vol.31 (3), p.107531, Article 107531

2020

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Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

Oncotarget, 2014-06, Vol.5 (12), p.4305-4319

2014

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Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (2), p.726-731

2010

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Induction of the permeability transition pore in cells depleted of mitochondrial DNA

Biochimica et biophysica acta, 2012-10, Vol.1817 (10), p.1860-1866

2012

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Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1

Antioxidants & redox signaling, 2021-03, Vol.34 (7), p.505-516

2021

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Dynamically Shaping Chaperones. Allosteric Modulators of HSP90 Family as Regulatory Tools of Cell Metabolism in Neoplastic Progression

Frontiers in oncology, 2020-07, Vol.10, p.1177-1177

2020

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Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

Oncotarget, 2016-05, Vol.7 (22), p.32375-32393

2016

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Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis

Cell calcium (Edinburgh), 2011-09, Vol.50 (3), p.222-233

2011

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Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish

Cell death & disease, 2021-01, Vol.12 (1), p.100-18, Article 100

2021

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Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1

Cell reports (Cambridge), 2017-01, Vol.18 (3), p.659-672

2017

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Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

PloS one, 2008-03, Vol.3 (3), p.e1852-e1852

2008

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Nitric oxide-based regulation of metabolism: Hints from TRAP1 and SIRT3 crosstalk

Frontiers in molecular biosciences, 2022-07, Vol.9, p.942729

2022

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HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia

Cell death & disease, 2021-05, Vol.12 (5), p.434-434, Article 434

2021

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SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I

Oncotarget, 2014-05, Vol.5 (9), p.2418-2427

2014

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The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria

Disease models & mechanisms, 2019-03, Vol.12 (3)

2019

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Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment

Cell death & disease, 2024-04, Vol.15 (4), p.281-281, Article 281

2024

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Mitochondrial permeability transition in Ca2+ -dependent apoptosis and necrosis

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters

Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase

mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

The mitochondrial permeability transition pore and its adaptive responses in tumor cells

The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

Metabolic Plasticity of Tumor Cell Mitochondria

Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

Induction of the permeability transition pore in cells depleted of mitochondrial DNA

Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1

Dynamically Shaping Chaperones. Allosteric Modulators of HSP90 Family as Regulatory Tools of Cell Metabolism in Neoplastic Progression

Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis

Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish

Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

Nitric oxide-based regulation of metabolism: Hints from TRAP1 and SIRT3 crosstalk

HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia

SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I

The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria

Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment

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