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Evolution of the primate trypanolytic factor APOL1

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (20), p.E2130-E2139

2014

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Past and Ongoing Tsetse and Animal Trypanosomiasis Control Operations in Five African Countries: A Systematic Review

PLoS neglected tropical diseases, 2016-12, Vol.10 (12), p.e0005247-e0005247

2016

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Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

PLoS pathogens, 2015-06, Vol.11 (6), p.e1004942

2015

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A single test approach for accurate and sensitive detection and taxonomic characterization of Trypanosomes by comprehensive analysis of internal transcribed spacer 1 amplicons

PLoS neglected tropical diseases, 2019-02, Vol.13 (2), p.e0006842

2019

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Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

PLoS neglected tropical diseases, 2017-06, Vol.11 (6), p.e0005649-e0005649

2017

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Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity

eLife, 2020-05, Vol.9

2020

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Serial magnetic resonance imaging of splenomegaly in the Trypanosoma brucei infected mouse

PLoS neglected tropical diseases, 2022-12, Vol.16 (12), p.e0010962-e0010962

2022

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Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface

PLoS neglected tropical diseases, 2022-09, Vol.16 (9), p.e0010791-e0010791

2022

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Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006855-e1006855

2018

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A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei

PLoS neglected tropical diseases, 2020-09, Vol.14 (9), p.e0008568-e0008568

2020

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Structure of the trypanosome haptoglobin–hemoglobin receptor and implications for nutrient uptake and innate immunity

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1905-1910

2013

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The phosphoinositide regulatory network in Trypanosoma brucei: Implications for cell-wide regulation in eukaryotes

PLoS neglected tropical diseases, 2020-10, Vol.14 (10), p.e0008689

2020

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Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

PLoS neglected tropical diseases, 2017-03, Vol.11 (3), p.e0005432

2017

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Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug

PLoS neglected tropical diseases, 2021-04, Vol.15 (4), p.e0009276

2021

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The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham's discovery 50 years ago to a gold standard for sleeping sickness diagnosis

PLoS neglected tropical diseases, 2019-02, Vol.13 (2), p.e0007051

2019

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A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

PLoS neglected tropical diseases, 2019-05, Vol.13 (5), p.e0007373-e0007373

2019

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Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase

PLoS neglected tropical diseases, 2016-08, Vol.10 (8), p.e0004791-e0004791

2016

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Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome

PLoS neglected tropical diseases, 2020-03, Vol.14 (3), p.e0007790

2020

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Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B

PLoS neglected tropical diseases, 2018-09, Vol.12 (9), p.e0006790-e0006790

2018

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Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase

PLoS neglected tropical diseases, 2013-11, Vol.7 (11), p.e2571

2013

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Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

PLoS neglected tropical diseases, 2016-11, Vol.10 (11), p.e0005125

2016

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Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

PLoS neglected tropical diseases, 2013-01, Vol.7 (1), p.e2012

2013

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In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis

PLoS neglected tropical diseases, 2013, Vol.7 (8), p.e2384

2013

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A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

PLoS neglected tropical diseases, 2017-10, Vol.11 (10), p.e0005979-e0005979

2017

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Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase

PLoS neglected tropical diseases, 2016-05, Vol.10 (5), p.e0004714-e0004714

2016

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Evolution of the primate trypanolytic factor APOL1

Past and Ongoing Tsetse and Animal Trypanosomiasis Control Operations in Five African Countries: A Systematic Review

Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

A single test approach for accurate and sensitive detection and taxonomic characterization of Trypanosomes by comprehensive analysis of internal transcribed spacer 1 amplicons

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity

Serial magnetic resonance imaging of splenomegaly in the Trypanosoma brucei infected mouse

Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1

A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei

Structure of the trypanosome haptoglobin–hemoglobin receptor and implications for nutrient uptake and innate immunity

The phosphoinositide regulatory network in Trypanosoma brucei: Implications for cell-wide regulation in eukaryotes

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug

The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham's discovery 50 years ago to a gold standard for sleeping sickness diagnosis

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase

Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome

Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase

Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase

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