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Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer’s Drug Discovery

Molecular neurobiology, 2016-08, Vol.53 (6), p.3565-3575

2016

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Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications

Analytical chemistry (Washington), 2017-01, Vol.89 (1), p.910-915

2017

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Positively Charged Chitosan and N‑Trimethyl Chitosan Inhibit Aβ40 Fibrillogenesis

Biomacromolecules, 2015-08, Vol.16 (8), p.2363-2373

2015

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Synthesis and characterization of asymmetrical gemini surfactants

Physical chemistry chemical physics : PCCP, 2017, Vol.19 (3), p.1953-1962

2017

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Curcumin Binding to Beta Amyloid: A Computational Study

Chemical biology & drug design, 2015-10, Vol.86 (4), p.813-820

2015

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Modeling the Inhibition Kinetics of Curcumin, Orange G, and Resveratrol with Amyloid‑β Peptide

ACS omega, 2021-03, Vol.6 (12), p.8680-8686

2021

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Design, synthesis and structure–activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors

Bioorganic & medicinal chemistry, 2011-04, Vol.19 (7), p.2269-2281

2011

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Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents

Bioorganic & medicinal chemistry, 2012-05, Vol.20 (9), p.2912-2922

2012

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Differential Effects of Endocannabinoids on Amyloid-Beta Aggregation and Toxicity

International journal of molecular sciences, 2023-01, Vol.24 (2), p.911

2023

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Synthesis and Structure−Activity Relationship Studies of 1,3-Diarylprop-2-yn-1-ones: Dual Inhibitors of Cyclooxygenases and Lipoxygenases

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1668-1683

2006

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Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4872-4882

2003

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Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors

Bioorganic & medicinal chemistry, 2006-10, Vol.14 (20), p.7044-7050

2006

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Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells

Frontiers in pharmacology, 2022-12, Vol.13, p.1086894-1086894

2022

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Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy

Cancers, 2020-08, Vol.12 (8), p.2121

2020

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Interactions of Selective Serotonin Reuptake Inhibitors with β‑Amyloid

ACS chemical neuroscience, 2019-01, Vol.10 (1), p.226-234

2019

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Tau Derived Hexapeptide AcPHF6 Promotes Beta-Amyloid (Aβ) Fibrillogenesis

ACS chemical neuroscience, 2018-04, Vol.9 (4), p.773-782

2018

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Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry

European journal of medicinal chemistry, 2016-05, Vol.113, p.258-272

2016

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Isomeric acetoxy analogs of celecoxib and their evaluation as cyclooxygenase inhibitors

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (20), p.6074-6080

2011

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Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: Dual Inhibitors of cyclooxygenases and 5-lipoxygenase

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2168-2173

2010

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Design, Synthesis, and Structure−Activity Relationship Studies of 3,4,6-Triphenylpyran-2-ones as Selective Cyclooxygenase-2 Inhibitors

Journal of medicinal chemistry, 2004-07, Vol.47 (16), p.3972-3990

2004

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Drug Repurposing: Dipeptidyl Peptidase IV (DPP4) Inhibitors as Potential Agents to Treat SARS-CoV-2 (2019-nCoV) Infection

Pharmaceuticals (Basel, Switzerland), 2021-01, Vol.14 (1), p.44

2021

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2,4-Disubstituted quinazolines as amyloid-β aggregation inhibitors with dual cholinesterase inhibition and antioxidant properties: Development and structure-activity relationship (SAR) studies

European journal of medicinal chemistry, 2017-01, Vol.126, p.823-843

2017

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Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7716-7727

2006

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Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs)

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7898-7909

2006

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Development and evaluation of multifunctional agents for potential treatment of Alzheimer’s disease: Application to a pyrimidine-2,4-diamine template

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4707-4712

2012

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Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer’s Drug Discovery

Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications

Positively Charged Chitosan and N‑Trimethyl Chitosan Inhibit Aβ40 Fibrillogenesis

Synthesis and characterization of asymmetrical gemini surfactants

Curcumin Binding to Beta Amyloid: A Computational Study

Modeling the Inhibition Kinetics of Curcumin, Orange G, and Resveratrol with Amyloid‑β Peptide

Design, synthesis and structure–activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors

Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents

Differential Effects of Endocannabinoids on Amyloid-Beta Aggregation and Toxicity

Synthesis and Structure−Activity Relationship Studies of 1,3-Diarylprop-2-yn-1-ones: Dual Inhibitors of Cyclooxygenases and Lipoxygenases

Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors

Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells

Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy

Interactions of Selective Serotonin Reuptake Inhibitors with β‑Amyloid

Tau Derived Hexapeptide AcPHF6 Promotes Beta-Amyloid (Aβ) Fibrillogenesis

Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry

Isomeric acetoxy analogs of celecoxib and their evaluation as cyclooxygenase inhibitors

Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: Dual Inhibitors of cyclooxygenases and 5-lipoxygenase

Design, Synthesis, and Structure−Activity Relationship Studies of 3,4,6-Triphenylpyran-2-ones as Selective Cyclooxygenase-2 Inhibitors

Drug Repurposing: Dipeptidyl Peptidase IV (DPP4) Inhibitors as Potential Agents to Treat SARS-CoV-2 (2019-nCoV) Infection

2,4-Disubstituted quinazolines as amyloid-β aggregation inhibitors with dual cholinesterase inhibition and antioxidant properties: Development and structure-activity relationship (SAR) studies

Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases

Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs)

Development and evaluation of multifunctional agents for potential treatment of Alzheimer’s disease: Application to a pyrimidine-2,4-diamine template

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