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Molecular mechanisms of glioma invasiveness: the role of proteases

Nature reviews. Cancer, 2003-07, Vol.3 (7), p.489-501

Rao, Jasti S

2003

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MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells

PloS one, 2011-06, Vol.6 (6), p.e20614

2011

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Intermittent hypoxia regulates stem-like characteristics and differentiation of neuroblastoma cells

PloS one, 2012-02, Vol.7 (2), p.e30905

2012

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Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway

PloS one, 2010-04, Vol.5 (4), p.e10350-e10350

2010

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Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity

Oncotarget, 2012-11, Vol.3 (11), p.1439-1454

2012

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Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells

BMC cancer, 2010-11, Vol.10 (1), p.647-647, Article 647

2010

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Suppression of tumor cell invasiveness and in vivo tumor growth by microRNA-874 in non-small cell lung cancer

Biochemical and biophysical research communications, 2013-05, Vol.434 (3), p.627-633

2013

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Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP)

PloS one, 2010-07, Vol.5 (7), p.e11813-e11813

2010

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Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion

Molecular neurobiology, 2014-02, Vol.49 (1), p.50-65

2014

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Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression

Carcinogenesis (New York), 2013-03, Vol.34 (3), p.550-559

2013

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Concepts in in vivo siRNA delivery for cancer therapy

Journal of cellular physiology, 2009-08, Vol.220 (2), p.285-291

2009

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Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas

PloS one, 2010-10, Vol.5 (10), p.e13731-e13731

2010

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Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer

Molecular biology of the cell, 2013-09, Vol.24 (17), p.2620-2632

2013

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Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma

PloS one, 2012-09, Vol.7 (9), p.e44798

2012

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p53- and Bax-Mediated Apoptosis in Injured Rat Spinal Cord

Neurochemical research, 2011-11, Vol.36 (11), p.2063-2074

2011

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Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells

Cancer letters, 2011-12, Vol.313 (1), p.64-75

2011

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Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma

PloS one, 2010-09, Vol.5 (9), p.e13006

2010

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Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor

Molecular cancer, 2011-10, Vol.10 (1), p.130-130, Article 130

2011

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Suppression of the uPAR-uPA system retards angiogenesis, invasion, and in vivo tumor development in pancreatic cancer cells

Molecular cancer research, 2011-04, Vol.9 (4), p.377-389

2011

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RNA Interference-directed Knockdown of Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Inhibits Prostate Cancer Cell Invasion, Survival, and Tumorigenicity in Vivo

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36529-36540

2005

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Effects of irradiation on tumor cell survival, invasion and angiogenesis

Journal of neuro-oncology, 2010-12, Vol.100 (3), p.323-338

2010

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Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis

Oncogene, 2004-06, Vol.23 (27), p.4681-4689

2004

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Cathepsin B as a cancer target

Expert opinion on therapeutic targets, 2013-03, Vol.17 (3), p.281-291

2013

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YKL-40 and Matrix Metalloproteinase-9 as Potential Serum Biomarkers for Patients with High-Grade Gliomas

Clinical cancer research, 2006-10, Vol.12 (19), p.5698-5704

2006

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Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (3), p.930-939

2007

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Molecular mechanisms of glioma invasiveness: the role of proteases

MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells

Intermittent hypoxia regulates stem-like characteristics and differentiation of neuroblastoma cells

Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway

Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity

Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells

Suppression of tumor cell invasiveness and in vivo tumor growth by microRNA-874 in non-small cell lung cancer

Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP)

Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion

Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression

Concepts in in vivo siRNA delivery for cancer therapy

Downregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas

Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer

Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma

p53- and Bax-Mediated Apoptosis in Injured Rat Spinal Cord

Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells

Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma

Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor

Suppression of the uPAR-uPA system retards angiogenesis, invasion, and in vivo tumor development in pancreatic cancer cells

RNA Interference-directed Knockdown of Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Inhibits Prostate Cancer Cell Invasion, Survival, and Tumorigenicity in Vivo

Effects of irradiation on tumor cell survival, invasion and angiogenesis

Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis

Cathepsin B as a cancer target

YKL-40 and Matrix Metalloproteinase-9 as Potential Serum Biomarkers for Patients with High-Grade Gliomas

Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer

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