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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?

Cold Spring Harbor perspectives in biology, 2016-10, Vol.8 (10), p.a023614

2016

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Anticancer Therapeutic Strategies Targeting p53 Aggregation

International journal of molecular sciences, 2022-10, Vol.23 (19), p.11023

2022

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Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

Bioscience reports, 2013-07, Vol.33 (4), p.e00054

2013

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The aggregation of mutant p53 produces prion-like properties in cancer

Prion, 2014-01, Vol.8 (1), p.75-84

2014

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Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer

Frontiers in oncology, 2015-04, Vol.5, p.97

2015

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Recent Synthetic Approaches towards Small Molecule Reactivators of p53

Biomolecules (Basel, Switzerland), 2020-04, Vol.10 (4), p.635

2020

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PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma

Frontiers in molecular biosciences, 2023-04, Vol.10, p.1165132-1165132

2023

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p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells

The Journal of biological chemistry, 2019-03, Vol.294 (10), p.3670-3682

2019

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Prion-like aggregation of mutant p53 in cancer

Trends in biochemical sciences (Amsterdam. Regular ed.), 2014-06, Vol.39 (6), p.260-267

2014

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Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer

The Journal of biological chemistry, 2012-08, Vol.287 (33), p.28152-28162

2012

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Resveratrol prevents p53 aggregation in vitro and in breast cancer cells

Oncotarget, 2018-06, Vol.9 (49), p.29112-29122

2018

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RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

Scientific reports, 2019-08, Vol.9 (1), p.12406-12, Article 12406

2019

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Balance between S -nitrosylation and denitrosylation modulates myoblast proliferation independently of soluble guanylyl cyclase activation

American Journal of Physiology: Cell Physiology, 2017-07, Vol.313 (1), p.C11-C26

2017

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Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia

Journal of cellular biochemistry, 2019-10, Vol.120 (10), p.17108-17122

2019

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Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids

Journal of biological inorganic chemistry, 2014-08, Vol.19 (6), p.839-851

2014

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Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion

Methods (San Diego, Calif.), 2011-03, Vol.53 (3), p.306-317

2011

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Oroidin Inhibits the Activity of the Multidrug Resistance Target Pdr5p from Yeast Plasma Membranes

Journal of natural products (Washington, D.C.), 2011-02, Vol.74 (2), p.279-282

2011

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Putative role of an ABC transporter in Fonsecaea pedrosoi multidrug resistance

International journal of antimicrobial agents, 2012-11, Vol.40 (5), p.409-415, Article 409

2012

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Evaluation of the pathophysiological role of PrP:RNA interaction

The FASEB journal, 2011-04, Vol.25, p.708.5-708.5

2011

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Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils

The Journal of biological chemistry, 2012-08, Vol.287 (33), p.28152-28162

2012

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Understanding the winning strategies used by the bloom-forming cyanobacterium Cylindrospermopsis raciborskii

Harmful algae, 2016-04, Vol.54, p.44-53

2016

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Low- or high-white light irradiance induces similar conidial stress tolerance in Metarhizium robertsii

Archives of microbiology, 2022-01, Vol.204 (1), p.83-83, Article 83

2022

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Conidiation under illumination enhances conidial tolerance of insect-pathogenic fungi to environmental stresses

Fungal biology, 2021-11, Vol.125 (11), p.891-904

2021

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Insights on the freshwater microbiomes metabolic changes associated with the world's largest mining disaster

The Science of the total environment, 2019-03, Vol.654, p.1209-1217

2019

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Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells

The Journal of biological chemistry, 2019-06, Vol.294 (24), p.9430-9439

2019

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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?

Anticancer Therapeutic Strategies Targeting p53 Aggregation

Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

The aggregation of mutant p53 produces prion-like properties in cancer

Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer

Recent Synthetic Approaches towards Small Molecule Reactivators of p53

PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma

p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells

Prion-like aggregation of mutant p53 in cancer

Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer

Resveratrol prevents p53 aggregation in vitro and in breast cancer cells

RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

Balance between S -nitrosylation and denitrosylation modulates myoblast proliferation independently of soluble guanylyl cyclase activation

Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia

Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids

Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion

Oroidin Inhibits the Activity of the Multidrug Resistance Target Pdr5p from Yeast Plasma Membranes

Putative role of an ABC transporter in Fonsecaea pedrosoi multidrug resistance

Evaluation of the pathophysiological role of PrP:RNA interaction

Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils

Understanding the winning strategies used by the bloom-forming cyanobacterium Cylindrospermopsis raciborskii

Low- or high-white light irradiance induces similar conidial stress tolerance in Metarhizium robertsii

Conidiation under illumination enhances conidial tolerance of insect-pathogenic fungi to environmental stresses

Insights on the freshwater microbiomes metabolic changes associated with the world's largest mining disaster

Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells

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