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F-box protein interactions with the hallmark pathways in cancer

Seminars in cancer biology, 2016-02, Vol.36, p.3-17

2016

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The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration

Brain research, 2018-08, Vol.1693 (Pt A), p.11-23

2018

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Structure and Function of Fbxo7/PARK15 in Parkinson's Disease

Current protein & peptide science, 2017-01, Vol.18 (7), p.715-724

2017

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The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

Nature neuroscience, 2013-09, Vol.16 (9), p.1257-1265

2013

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Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

Open biology, 2013-10, Vol.3 (10), p.130131-130131

2013

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Loss of FBXO7 results in a Parkinson's‐like dopaminergic degeneration via an RPL23–MDM2–TP53 pathway

The Journal of pathology, 2019-10, Vol.249 (2), p.241-254

2019

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Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression

The Journal of pathology, 2015-10, Vol.237 (2), p.263-272

2015

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Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Biochemical journal, 2016-10, Vol.473 (20), p.3563-3580

2016

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Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors

Nature communications, 2022-10, Vol.13 (1), p.6021-10, Article 6021

2022

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Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27

Cellular and molecular life sciences : CMLS, 2017-04, Vol.74 (8), p.1553-1566

2017

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The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

Biochimica et biophysica acta. General subjects, 2021-01, Vol.1865 (1), p.129754-129754, Article 129754

2021

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Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

Journal of cell science, 2011-07, Vol.124 (Pt 13), p.2175-2186

2011

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Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis

PloS one, 2011-06, Vol.6 (6), p.e21165

2011

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A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling

Frontiers in physiology, 2019-10, Vol.10, p.1278-1278

2019

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Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration

The American journal of pathology, 2009-10, Vol.175 (4), p.1598-1609

2009

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Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

Biochemical and biophysical research communications, 2021-05, Vol.554, p.41-48

2021

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Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

Development (Cambridge), 2011-07, Vol.138 (14), p.e1-e1

2011

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Aβ40 Inhibits Amyloid Deposition In Vivo

The Journal of neuroscience, 2007-01, Vol.27 (3), p.627-633

2007

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Abstract P2-13-23: Activity and tolerability of combination of trastuzumab deruxtecan with the pan-AKT inhibitor capivasertib in preclinical HER2+ and HER2-low breast cancer models

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P2-P2-13-23

2022

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Abstract P2-13-18: Activity and tolerability of combination of trastuzumab deruxtecan with olaparib in preclinical HER2+ and HER2-low breast cancer models

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P2-P2-13-18

2022

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Changes in ABC Transporter Expression during Hematopoiesis Cause Lineage-Biased Cytopenias in Patients Treated with Aurora Kinase Inhibitors

Blood, 2021-11, Vol.138 (Supplement 1), p.4292-4292

2021

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A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease

Neurochemistry international, 2010-07, Vol.56 (8), p.937-947

2010

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P2-172: Wild-type mouse tau transgenic model: Halfway to a complete AD model

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T421-T421

2008

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Abstract 5298: Activity and tolerability of combinations of trastuzumab deruxtecan (T-DXd) with inhibitors of the DNA damage response in preclinical models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5298-5298

2022

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F-box protein interactions with the hallmark pathways in cancer

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration

Structure and Function of Fbxo7/PARK15 in Parkinson's Disease

The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

Loss of FBXO7 results in a Parkinson's‐like dopaminergic degeneration via an RPL23–MDM2–TP53 pathway

Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors

Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27

The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling

Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration

Analysis of the FBXO7 promoter reveals overlapping Pax5 and c-Myb binding sites functioning in B cells

Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

Aβ40 Inhibits Amyloid Deposition In Vivo

Abstract P2-13-23: Activity and tolerability of combination of trastuzumab deruxtecan with the pan-AKT inhibitor capivasertib in preclinical HER2+ and HER2-low breast cancer models

Abstract P2-13-18: Activity and tolerability of combination of trastuzumab deruxtecan with olaparib in preclinical HER2+ and HER2-low breast cancer models

Changes in ABC Transporter Expression during Hematopoiesis Cause Lineage-Biased Cytopenias in Patients Treated with Aurora Kinase Inhibitors

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease

P2-172: Wild-type mouse tau transgenic model: Halfway to a complete AD model

Abstract 5298: Activity and tolerability of combinations of trastuzumab deruxtecan (T-DXd) with inhibitors of the DNA damage response in preclinical models

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