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Optimizing Human Induced Pluripotent Stem Cell Expansion in Stirred-Suspension Culture

Stem cells and development, 2017-12, Vol.26 (24), p.1804-1817

2017

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Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

Stem cell research & therapy, 2021-01, Vol.12 (1), p.55-55, Article 55

2021

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Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury

Scientific reports, 2023-06, Vol.13 (1), p.9378-9378, Article 9378

2023

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Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors

Journal of biotechnology, 2019-10, Vol.304, p.16-27

2019

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Concise Review: Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells

Stem cells translational medicine, 2018-12, Vol.7 (12), p.867-875

2018

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Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells

PloS one, 2010-06, Vol.5 (6), p.e10998-e10998

2010

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Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection

Viruses, 2018-08, Vol.10 (8), p.421

2018

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Enhanced Osteogenic Differentiation of Pluripotent Stem Cells via γ-Secretase Inhibition

International journal of molecular sciences, 2021-05, Vol.22 (10), p.5215

2021

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Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

Stem cells translational medicine, 2020-09, Vol.9 (9), p.1036-1052

2020

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The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation

Stem cells and development, 2008-12, Vol.17 (6), p.1079-1086

2008

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Cell-Based Therapy Manufacturing in Stirred Suspension Bioreactor: Thoughts for cGMP Compliance

Frontiers in bioengineering and biotechnology, 2020-11, Vol.8, p.599674-599674

2020

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Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors

Tissue engineering. Part C, Methods, 2010-08, Vol.16 (4), p.573-582

2010

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Synergistic effect of medium, matrix, and exogenous factors on the adhesion and growth of human pluripotent stem cells under defined, xeno-free conditions

Stem cells and development, 2012-07, Vol.21 (11), p.2036-2048

2012

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Robust bioprocess design and evaluation of commercial media for the serial expansion of human induced pluripotent stem cell aggregate cultures in vertical-wheel bioreactors

Stem cell research & therapy, 2024-07, Vol.15 (1), p.232-19, Article 232

2024

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Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1502, p.53

2016

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Derivation of iPSCs in stirred suspension bioreactors

Nature methods, 2012-04, Vol.9 (5), p.465-466

2012

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Post-Passage rock inhibition induces cytoskeletal aberrations and apoptosis in Human embryonic stem cells

Stem cell research, 2019-12, Vol.41, p.101641-101641, Article 101641

2019

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Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina

Human molecular genetics, 2005-10, Vol.14 (20), p.3035-3046

2005

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Expansion and long-term maintenance of induced pluripotent stem cells in stirred suspension bioreactors

Journal of tissue engineering and regenerative medicine, 2012-06, Vol.6 (6), p.462-472

2012

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Human embryonic stem cells: caught between a ROCK inhibitor and a hard place

BioEssays, 2009-03, Vol.31 (3), p.336-343

2009

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Factorial experimental design for the culture of human embryonic stem cells as aggregates in stirred suspension bioreactors reveals the potential for interaction effects between bioprocess parameters

Tissue engineering. Part C, Methods, 2014-01, Vol.20 (1), p.76-89

2014

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A retinoid analogue, TTNPB, promotes clonal expansion of human pluripotent stem cells by upregulating CLDN2 and HoxA1

Communications biology, 2024-02, Vol.7 (1), p.190-190, Article 190

2024

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Shear stress influences the pluripotency of murine embryonic stem cells in stirred suspension bioreactors

Journal of tissue engineering and regenerative medicine, 2014-04, Vol.8 (4), p.268-278

2014

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Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

Scientific reports, 2013-06, Vol.3 (1), Article 1978

2013

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Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts

Cells (Basel, Switzerland), 2020-01, Vol.9 (1), p.191

2020

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Optimizing Human Induced Pluripotent Stem Cell Expansion in Stirred-Suspension Culture

Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury

Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors

Concise Review: Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells

Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells

Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection

Enhanced Osteogenic Differentiation of Pluripotent Stem Cells via γ-Secretase Inhibition

Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation

Cell-Based Therapy Manufacturing in Stirred Suspension Bioreactor: Thoughts for cGMP Compliance

Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors

Synergistic effect of medium, matrix, and exogenous factors on the adhesion and growth of human pluripotent stem cells under defined, xeno-free conditions

Robust bioprocess design and evaluation of commercial media for the serial expansion of human induced pluripotent stem cell aggregate cultures in vertical-wheel bioreactors

Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors

Derivation of iPSCs in stirred suspension bioreactors

Post-Passage rock inhibition induces cytoskeletal aberrations and apoptosis in Human embryonic stem cells

Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina

Expansion and long-term maintenance of induced pluripotent stem cells in stirred suspension bioreactors

Human embryonic stem cells: caught between a ROCK inhibitor and a hard place

Factorial experimental design for the culture of human embryonic stem cells as aggregates in stirred suspension bioreactors reveals the potential for interaction effects between bioprocess parameters

A retinoid analogue, TTNPB, promotes clonal expansion of human pluripotent stem cells by upregulating CLDN2 and HoxA1

Shear stress influences the pluripotency of murine embryonic stem cells in stirred suspension bioreactors

Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts

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