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ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

Anticancer research, 2009-11, Vol.29 (11), p.4373-4380

2009

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Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice

Toxicological sciences, 2009-03, Vol.108 (1), p.194-206

2009

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Spirocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species

Journal of medicinal chemistry, 2013-04, Vol.56 (8), p.3379-3403

2013

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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8‑Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (23), p.10112-10129

2014

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Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

Bioorganic & medicinal chemistry letters, 2014-06, Vol.24 (11), p.2477-2480

2014

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Abstract 2550: Combination of the KSP inhibitor ARRY-520 with bortezomib causes sustained tumor regressions and significantly increased time to regrowth in bortezomib sensitive and resistant models of multiple myeloma

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2550-2550

2011

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf super(V600E) kinase

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1923-1927

2014

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Abstract 2514: ARRY-162, A Potent and Selective MEK 1/2 Inhibitor, Shows Enhanced Efficacy in Combination with Other Targeted Kinase Inhibitors and with Chemotherapy

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2514-2514

2010

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Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma

Blood, 2009-11, Vol.114 (22), p.2858-2858

2009

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Discovery of a Novel Class of Imidazo[1,2‑a]Pyridines with Potent PDGFR Activity and Oral Bioavailability

ACS medicinal chemistry letters, 2014-01, Vol.5 (1), p.78-83

2014

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Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.2515-2515

2010

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The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3387-3391

2012

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Pyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

ACS medicinal chemistry letters, 2011-05, Vol.2 (5), p.342-347

2011

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The Conundrum of Patients With Compensated Cirrhosis Requiring Kidney Transplantation; Kidney Alone or Simultaneous Liver Kidney Transplantation

Transplantation, 2023-02, Vol.107 (2), p.429

2023

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18F-FDG PET/CT in left ventricular assist device infections: In-depth characterization and clinical implications

The Journal of heart and lung transplantation, 2024-04, Vol.43 (4), p.529-538

2024

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On differentiation between vasogenic edema and non-enhancing tumor in high-grade glioma patients using a support vector machine classifier based upon pre and post-surgery MRI images

European journal of radiology, 2018-09, Vol.106, p.199-208

2018

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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2015, Vol.386 (9995), p.743-800

2015

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Evaluation of the Denture Impact on the Palatal Rugae: An Original Research

Journal of pharmacy & bioallied science, 2023-07, Vol.15 (5), p.224-S229

2023

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Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2014, Vol.384 (9947), p.980-1004

2014

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A NOVEL DESIGN OF COMPACT MONOPOLE ANTENNA WITH DEFECTED GROUND PLANE FOR WIDEBAND APPLICATIONS

Progress in electromagnetics research M Pier M, 2018, Vol.70, p.21-31

2018

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ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

Inflammatory Biomarkers of Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide–Induced Skin Injury in SKH-1 Hairless Mice

Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Spirocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species

Discovery of 7‑Tetrahydropyran-2-yl Chromans: β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors That Reduce Amyloid β‑Protein (Aβ) in the Central Nervous System

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase

8‑Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

Abstract 2550: Combination of the KSP inhibitor ARRY-520 with bortezomib causes sustained tumor regressions and significantly increased time to regrowth in bortezomib sensitive and resistant models of multiple myeloma

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase

Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf super(V600E) kinase

Abstract 2514: ARRY-162, A Potent and Selective MEK 1/2 Inhibitor, Shows Enhanced Efficacy in Combination with Other Targeted Kinase Inhibitors and with Chemotherapy

Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma

Discovery of a Novel Class of Imidazo[1,2‑a]Pyridines with Potent PDGFR Activity and Oral Bioavailability

Abstract 2515: Preclinical Development of ARRY-162, A Potent and Selective MEK 1/2 Inhibitor

The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase

Pyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

The Conundrum of Patients With Compensated Cirrhosis Requiring Kidney Transplantation; Kidney Alone or Simultaneous Liver Kidney Transplantation

18F-FDG PET/CT in left ventricular assist device infections: In-depth characterization and clinical implications

On differentiation between vasogenic edema and non-enhancing tumor in high-grade glioma patients using a support vector machine classifier based upon pre and post-surgery MRI images

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Evaluation of the Denture Impact on the Palatal Rugae: An Original Research

Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

A NOVEL DESIGN OF COMPACT MONOPOLE ANTENNA WITH DEFECTED GROUND PLANE FOR WIDEBAND APPLICATIONS

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