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Tetrasubstituted Pyrrole Derivative Mimetics of Protein-Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells

Molecules (Basel, Switzerland), 2023-05, Vol.28 (10), p.4161

2023

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Exploring the Photodynamic Properties of Two Antiproliferative Benzodiazopyrrole Derivatives

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1246

2020

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Phosphonium Salt Displays Cytotoxic Effects Against Human Cancer Cell Lines

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (13), p.1796

2017

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Ultrasound-Assisted Extraction, Chemical Characterization, and Impact on Cell Viability of Food Wastes Derived from Southern Italy Autochthonous Citrus Fruits

Antioxidants, 2022-01, Vol.11 (2), p.285

2022

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Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals

Antioxidants, 2022-02, Vol.11 (3), p.437

2022

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Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives

Current pharmaceutical design, 2002-01, Vol.8 (8), p.615

2002

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Novel sterically hindered cannabinoid CB1 receptor ligands

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7510-7515

2008

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Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions

European journal of medicinal chemistry, 2023-01, Vol.246, p.114952, Article 114952

2023

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Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (22), p.7302-7312

2015

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Synthetic derivatives of natural cinnamic acids as potential anti‐colorectal cancer agents

Chemical biology & drug design, 2024-01, Vol.103 (1), p.e14415-n/a

2024

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Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability

European journal of medicinal chemistry, 2022-08, Vol.238, p.114409-114409, Article 114409

2022

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Pioneering first‐in‐class FAAH‐HDAC inhibitors as potential multitarget neuroprotective agents

Archiv der Pharmazie (Weinheim), 2023-12, Vol.356 (12), p.e2300410-n/a

2023

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Photo-control of cancer cell growth by benzodiazo N-substituted pyrrole derivatives

Journal of photochemistry and photobiology. A, Chemistry., 2019-05, Vol.377, p.109-118

2019

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Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization

Journal of medicinal chemistry, 2024-02, Vol.67 (3), p.1758-1782

2024

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Development of 1-(2-aminophenyl)pyrrole-based amides acting as human topoisomerase I inhibitors

Archiv der Pharmazie (Weinheim), 2023-10, Vol.356 (10), p.e2300270-e2300270

2023

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First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents

European journal of medicinal chemistry, 2017-09, Vol.138, p.438-457

2017

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Activation of the c-Jun N-terminal Kinase (JNK) Signaling Pathway Is Essential during PBOX-6-induced Apoptosis in Chronic Myelogenous Leukemia (CML) Cells

The Journal of biological chemistry, 2002-05, Vol.277 (21), p.18383-18389

2002

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Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis

Molecules (Basel, Switzerland), 2008-03, Vol.13 (4), p.749-761

2008

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Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy

European journal of medicinal chemistry, 2022-05, Vol.235, p.114274-114274, Article 114274

2022

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Interaction between Alzheimer's Aβ(25–35) peptide and phospholipid bilayers: The role of cholesterol

Biochimica et biophysica acta. Biomembranes, 2008-12, Vol.1778 (12), p.2710-2716

2008

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Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells

Investigational new drugs, 2020-06, Vol.38 (3), p.634-649

2020

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Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation

ChemMedChem, 2017-12, Vol.12 (24), p.2074-2085

2017

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Anti-Inflammatory, Antioxidant and Crystallographic Studies of N-Palmitoyl-ethanol Amine (PEA) Derivatives

Molecules (Basel, Switzerland), 2017-04, Vol.22 (4), p.616

2017

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Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach

ACS infectious diseases, 2022-08, Vol.8 (8), p.1687-1699

2022

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Tetrasubstituted Pyrrole Derivative Mimetics of Protein-Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells

Exploring the Photodynamic Properties of Two Antiproliferative Benzodiazopyrrole Derivatives

Phosphonium Salt Displays Cytotoxic Effects Against Human Cancer Cell Lines

Ultrasound-Assisted Extraction, Chemical Characterization, and Impact on Cell Viability of Food Wastes Derived from Southern Italy Autochthonous Citrus Fruits

Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals

Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives

Novel sterically hindered cannabinoid CB1 receptor ligands

Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions

Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes

Synthetic derivatives of natural cinnamic acids as potential anti‐colorectal cancer agents

Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability

Pioneering first‐in‐class FAAH‐HDAC inhibitors as potential multitarget neuroprotective agents

Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy

Photo-control of cancer cell growth by benzodiazo N-substituted pyrrole derivatives

Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization

Development of 1-(2-aminophenyl)pyrrole-based amides acting as human topoisomerase I inhibitors

First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents

Activation of the c-Jun N-terminal Kinase (JNK) Signaling Pathway Is Essential during PBOX-6-induced Apoptosis in Chronic Myelogenous Leukemia (CML) Cells

Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis

Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy

Interaction between Alzheimer's Aβ(25–35) peptide and phospholipid bilayers: The role of cholesterol

Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells

Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation

Anti-Inflammatory, Antioxidant and Crystallographic Studies of N-Palmitoyl-ethanol Amine (PEA) Derivatives

Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach

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