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SARS-CoV-2 Spike Protein Disrupts Blood–Brain Barrier Integrity via RhoA Activation

Journal of neuroimmune pharmacology, 2021-12, Vol.16 (4), p.722-728

2021

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The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

Neurobiology of disease, 2020-12, Vol.146, p.105131-105131, Article 105131

2020

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HIV infects astrocytes in vivo and egresses from the brain to the periphery

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008381-e1008381

2020

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Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

Fluids and barriers of the CNS, 2018-07, Vol.15 (1), p.19-19, Article 19

2018

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Trafficking of adeno‐associated virus vectors across a model of the blood–brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

Journal of neurochemistry, 2017-01, Vol.140 (2), p.216-230

2017

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Emerging Roles of Pericytes in the Regulation of the Neurovascular Unit in Health and Disease

Journal of neuroimmune pharmacology, 2014-12, Vol.9 (5), p.591-605

2014

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Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions

The Journal of neuroscience, 2012-03, Vol.32 (12), p.4004-4016

2012

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Mechanism of alcohol-induced oxidative stress and neuronal injury

Free radical biology & medicine, 2008-12, Vol.45 (11), p.1542-1550

2008

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Dysfunction of brain pericytes in chronic neuroinflammation

Journal of cerebral blood flow and metabolism, 2016-04, Vol.36 (4), p.794-807

2016

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Blood-brain barrier: structural components and function under physiologic and pathologic conditions

Journal of neuroimmune pharmacology, 2006-09, Vol.1 (3), p.223-236

2006

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Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood–brain barrier dysfunction

Journal of neurochemistry, 2007-04, Vol.101 (2), p.566-576

2007

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Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5

PloS one, 2013-02, Vol.8 (2), p.e55972-e55972

2013

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Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Scientific reports, 2017-06, Vol.7 (1), p.3846-15, Article 3846

2017

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ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood brain barrier modulation

Journal of cerebral blood flow and metabolism, 2021-09, Vol.41 (9), p.2242-2255

2021

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Selection of an Efficient AAV Vector for Robust CNS Transgene Expression

Molecular therapy. Methods & clinical development, 2019-12, Vol.15, p.320-332

2019

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Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury

Frontiers in cellular neuroscience, 2016-02, Vol.10, p.43-43

2016

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Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells

Journal of cerebral blood flow and metabolism, 2009-12, Vol.29 (12), p.1933-1945

2009

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Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier

Nature protocols, 2010-07, Vol.5 (7), p.1265-1272

2010

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Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells

The American journal of pathology, 2008-02, Vol.172 (2), p.521-533

2008

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Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier

Frontiers in cell and developmental biology, 2024-10, Vol.12, p.1476386

2024

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The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties

Journal of neuroinflammation, 2021-03, Vol.18 (1), p.63-15, Article 63

2021

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Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo

PloS one, 2013-10, Vol.8 (10), p.e77002

2013

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HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions

Brain, behavior, and immunity, 2011-06, Vol.25 (Suppl 1), p.S61-S70

2011

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Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists

Journal of leukocyte biology, 2013-05, Vol.93 (5), p.801-810

2013

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SARS-CoV-2 Spike Protein Disrupts Blood–Brain Barrier Integrity via RhoA Activation

The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

HIV infects astrocytes in vivo and egresses from the brain to the periphery

Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

Trafficking of adeno‐associated virus vectors across a model of the blood–brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

Emerging Roles of Pericytes in the Regulation of the Neurovascular Unit in Health and Disease

Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions

Mechanism of alcohol-induced oxidative stress and neuronal injury

Dysfunction of brain pericytes in chronic neuroinflammation

Blood-brain barrier: structural components and function under physiologic and pathologic conditions

Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood–brain barrier dysfunction

Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5

Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood brain barrier modulation

Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

Selection of an Efficient AAV Vector for Robust CNS Transgene Expression

Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury

Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells

Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier

Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells

Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier

The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties

Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo

HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions

Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists

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