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Lysine Acetyltransferases (KATs) in Disguise: Diseases Implications

Journal of biochemistry (Tokyo), 2023-05, Vol.173 (6), p.417-433

2023

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Phase III, Randomized, Double-blind, Placebo controlled trial of Efficacy, Safety and Tolerability of Antiviral drug Umifenovir vs Standard care of therapy in non-severe COVID-19 patients

International journal of infectious diseases, 2022-02, Vol.115, p.62-69

2022

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NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis

The Journal of biological chemistry, 2005-08, Vol.280 (34), p.30273-30281

2005

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Small molecule adiponectin receptor agonist GTDF protects against skeletal muscle atrophy

Molecular and cellular endocrinology, 2017-01, Vol.439, p.273-285

2017

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Molecular determinants associated with temporal succession of SARS-CoV-2 variants in Uttar Pradesh, India

Frontiers in microbiology, 2023-02, Vol.14, p.986729-986729

2023

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Characterization of M. tuberculosis SerB2, an essential HAD-family phosphatase, reveals novel properties

PloS one, 2014-12, Vol.9 (12), p.e115409-e115409

2014

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Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis

The Journal of biological chemistry, 2008-12, Vol.283 (52), p.36532-36541

2008

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M. tuberculosis sliding β-clamp does not interact directly with the NAD+-dependent DNA ligase

PloS one, 2012-04, Vol.7 (4), p.e35702

2012

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Biochemical characterization and novel inhibitor identification of Mycobacterium tuberculosis Endonuclease VIII 2 (Rv3297)

Biochemistry and biophysics reports, 2017-12, Vol.12 (C), p.20-28

2017

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Crystal structure of the hexachlorocyclohexane dehydrochlorinase (LinA-type2): mutational analysis, thermostability and enantioselectivity

PloS one, 2012-11, Vol.7 (11), p.e50373

2012

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Dynamics of physical interaction between HIV-1 Nef and ASK1: identifying the interacting motif(s)

PloS one, 2013-06, Vol.8 (6), p.e67586

2013

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A novel dimer-tetramer transition captured by the crystal structure of the HIV-1 Nef

PloS one, 2011-11, Vol.6 (11), p.e26629

2011

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Mycobacterium tuberculosis Endonuclease VIII 2 (Nei2) forms a prereplicative BER complex with DnaN: Identification, characterization, and disruption of complex formation

Molecular microbiology, 2022-02, Vol.117 (2), p.320-333

2022

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Crystal structure of the Bacillus anthracis nucleoside diphosphate kinase and its characterization reveals an enzyme adapted to perform under stress conditions

Proteins, structure, function, and bioinformatics, 2009-08, Vol.76 (2), p.496-506

2009

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Mutational studies on HslU and its docking mode with HslV

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14103-14108

2000

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Salt bridges at the subdomain interfaces of the adenylation domain and active‐site residues of Mycobacterium tuberculosis NAD+‐dependent DNA ligase A (MtbLigA) are important for the initial steps of nick‐sealing activity

Acta crystallographica. Section D, Biological crystallography., 2021-06, Vol.77 (6), p.776-789

2021

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Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A

Journal of structural biology, 2021-03, Vol.213 (1), p.107655, Article 107655

2021

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Exploring the positional importance of aromatic residues and lysine in the interactions of peptides with the Plasmodium falciparum Hsp70-1

Biochimica et biophysica acta, 2011-03, Vol.1814 (3), p.457-457

Ramachandran, Ravishankar

2011

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Mycobacterium tuberculosis Rv2324 is a multifunctional feast/famine regulatory protein involved in growth, DNA replication and damage control

International journal of biological macromolecules, 2023-12, Vol.252, p.126459-126459, Article 126459

2023

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Functional Interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (11), p.7396-7401

2002

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[Fe–S] biogenesis and unusual assembly of the ISC scaffold complex in the Plasmodium falciparum mitochondrion

Molecular microbiology, 2021-08, Vol.116 (2), p.606-623

2021

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Mycobacterium tuberculosis class II apurinic/apyrimidinic‐endonuclease/3′‐5′ exonuclease III exhibits DNA regulated modes of interaction with the sliding DNA β‐clamp

Molecular microbiology, 2015-10, Vol.98 (1), p.46-68

2015

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Regulation of futile ligation during early steps of BER in M. tuberculosis is carried out by a β-clamp-XthA-LigA tri-component complex

International journal of biological macromolecules, 2023-01, Vol.225, p.442-453

2023

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Hsp70-1 from Plasmodium falciparum: Protein stability, domain analysis and chaperone activity

Biophysical chemistry, 2009-06, Vol.142 (1), p.55-64

2009

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Lysine Acetyltransferases (KATs) in Disguise: Diseases Implications

Phase III, Randomized, Double-blind, Placebo controlled trial of Efficacy, Safety and Tolerability of Antiviral drug Umifenovir vs Standard care of therapy in non-severe COVID-19 patients

NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis

Small molecule adiponectin receptor agonist GTDF protects against skeletal muscle atrophy

Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-γ and synergizes with imatinib to inhibit chronic myeloid leukemia cells

Molecular determinants associated with temporal succession of SARS-CoV-2 variants in Uttar Pradesh, India

Characterization of M. tuberculosis SerB2, an essential HAD-family phosphatase, reveals novel properties

Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis

M. tuberculosis sliding β-clamp does not interact directly with the NAD+-dependent DNA ligase

Biochemical characterization and novel inhibitor identification of Mycobacterium tuberculosis Endonuclease VIII 2 (Rv3297)

Crystal structure of the hexachlorocyclohexane dehydrochlorinase (LinA-type2): mutational analysis, thermostability and enantioselectivity

Dynamics of physical interaction between HIV-1 Nef and ASK1: identifying the interacting motif(s)

A novel dimer-tetramer transition captured by the crystal structure of the HIV-1 Nef

Mycobacterium tuberculosis Endonuclease VIII 2 (Nei2) forms a prereplicative BER complex with DnaN: Identification, characterization, and disruption of complex formation

Crystal structure of the Bacillus anthracis nucleoside diphosphate kinase and its characterization reveals an enzyme adapted to perform under stress conditions

Mutational studies on HslU and its docking mode with HslV

Salt bridges at the subdomain interfaces of the adenylation domain and active‐site residues of Mycobacterium tuberculosis NAD+‐dependent DNA ligase A (MtbLigA) are important for the initial steps of nick‐sealing activity

Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A

Exploring the positional importance of aromatic residues and lysine in the interactions of peptides with the Plasmodium falciparum Hsp70-1

Mycobacterium tuberculosis Rv2324 is a multifunctional feast/famine regulatory protein involved in growth, DNA replication and damage control

Functional Interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

[Fe–S] biogenesis and unusual assembly of the ISC scaffold complex in the Plasmodium falciparum mitochondrion

Mycobacterium tuberculosis class II apurinic/apyrimidinic‐endonuclease/3′‐5′ exonuclease III exhibits DNA regulated modes of interaction with the sliding DNA β‐clamp

Regulation of futile ligation during early steps of BER in M. tuberculosis is carried out by a β-clamp-XthA-LigA tri-component complex

Hsp70-1 from Plasmodium falciparum: Protein stability, domain analysis and chaperone activity

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