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Computational Drug Repositioning: From Data to Therapeutics

Clinical pharmacology and therapeutics, 2013-04, Vol.93 (4), p.335-341

2013

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United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment

Ophthalmology (Rochester, Minn.), 2017-09, Vol.124 (9), p.1259-1270

2017

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Paclitaxel-Eluting versus Everolimus-Eluting Coronary Stents in Diabetes

The New England journal of medicine, 2015-10, Vol.373 (18), p.1709-1719

2015

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Applications of Connectivity Map in drug discovery and development

Drug discovery today, 2012-12, Vol.17 (23-24), p.1289-1298

2012

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An integrative network-based approach for drug target indication expansion

PloS one, 2021-07, Vol.16 (7), p.e0253614-e0253614

2021

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Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease

PloS one, 2019-04, Vol.14 (4), p.e0215033-e0215033

2019

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Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform

BMC bioinformatics, 2022-06, Vol.23 (1), p.1-232, Article 232

2022

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A Hidradenitis Suppurativa molecular disease signature derived from patient samples by high-throughput RNA sequencing and re-analysis of previously reported transcriptomic data sets

PloS one, 2023-04, Vol.18 (4), p.e0284047-e0284047

2023

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Serial evaluation of vascular responses after implantation of everolimus‐eluting coronary stent by optical coherence tomography

Catheterization and cardiovascular interventions, 2022-02, Vol.99 (2), p.381-390

2022

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Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci

Arteriosclerosis, thrombosis, and vascular biology, 2016-05, Vol.36 (5), p.928

2016

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Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models

PloS one, 2015-12, Vol.10 (12), p.e0145499-e0145499

2015

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U.S. Multicenter Clinical Trial of Corneal Collagen Crosslinking for Treatment of Corneal Ectasia after Refractive Surgery

Ophthalmology (Rochester, Minn.), 2017-10, Vol.124 (10), p.1475-1484

2017

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Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

BMC bioinformatics, 2018-10, Vol.19 (1), p.345-345, Article 345

2018

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Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

PloS one, 2015-08, Vol.10 (8), p.e0134927-e0134927

2015

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Impact of Medication Nonadherence in a Clinical Trial of Dual Antiplatelet Therapy

Journal of the American College of Cardiology, 2022-08, Vol.80 (8), p.766-778

2022

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TCTAP A-002 Evaluation of Vascular Response and Healing After Implantation of Tetrilimus Everolimus-eluting Coronary Stent by Optical Coherence Tomography (EVER-OCT): 3 and 6 Month Serial Analysis

Journal of the American College of Cardiology, 2019-04, Vol.73 (15), p.S1-S1

2019

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Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway

PloS one, 2017-11, Vol.12 (11), p.e0186405-e0186405

2017

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Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository

Frontiers in medicine, 2022-06, Vol.9, p.903838-903838

2022

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TCT-457 Paclitaxel - eluting stents vs Everolimus - eluting Coronary Stents in a Diabetic population: 2 Years Follow-up of TUXEDO-India Trial

Journal of the American College of Cardiology, 2016-11, Vol.68 (18), p.B184-B184

2016

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Efficacy and safety of loteprednol etabonate 0.5% gel in the treatment of ocular inflammation and pain after cataract surgery

Journal of cataract and refractive surgery, 2013-02, Vol.39 (2), p.158-167

2013

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Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

Journal of investigative dermatology, 2017-10, Vol.137 (10), p.2110-2119

2017

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

Journal of the American Heart Association, 2017-05, Vol.6 (5)

2017

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Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes

Science (American Association for the Advancement of Science), 1996-04, Vol.272 (5261), p.557-560

1996

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Multi-omics integration reveals molecular networks and regulators of psoriasis

BMC systems biology, 2019-01, Vol.13 (1), p.8-8, Article 8

2019

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Transradial access for coronary diagnostic and interventional procedures: Consensus statement and recommendations for India: Advancing Complex CoronariES Sciences through TransRADIAL intervention in India - ACCESS RADIAL™: Clinical consensus recommendations in collaboration with Cardiological Society of India (CSI)

Indian heart journal, 2018-11, Vol.70 (6), p.922-933

2018

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Computational Drug Repositioning: From Data to Therapeutics

United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment

Paclitaxel-Eluting versus Everolimus-Eluting Coronary Stents in Diabetes

Applications of Connectivity Map in drug discovery and development

An integrative network-based approach for drug target indication expansion

Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease

Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform

A Hidradenitis Suppurativa molecular disease signature derived from patient samples by high-throughput RNA sequencing and re-analysis of previously reported transcriptomic data sets

Serial evaluation of vascular responses after implantation of everolimus‐eluting coronary stent by optical coherence tomography

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci

Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models

U.S. Multicenter Clinical Trial of Corneal Collagen Crosslinking for Treatment of Corneal Ectasia after Refractive Surgery

Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

Impact of Medication Nonadherence in a Clinical Trial of Dual Antiplatelet Therapy

TCTAP A-002 Evaluation of Vascular Response and Healing After Implantation of Tetrilimus Everolimus-eluting Coronary Stent by Optical Coherence Tomography (EVER-OCT): 3 and 6 Month Serial Analysis

Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway

Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository

TCT-457 Paclitaxel - eluting stents vs Everolimus - eluting Coronary Stents in a Diabetic population: 2 Years Follow-up of TUXEDO-India Trial

Efficacy and safety of loteprednol etabonate 0.5% gel in the treatment of ocular inflammation and pain after cataract surgery

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes

Multi-omics integration reveals molecular networks and regulators of psoriasis

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