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Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis

mBio, 2022-08, Vol.13 (4), p.e0142622-e0142622

2022

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Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

eLife, 2017-10, Vol.6

2017

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N -myristoyltransferase inhibitors as new leads to treat sleeping sickness

Nature, 2010-04, Vol.464 (7289), p.728-732

2010

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Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

The Journal of biological chemistry, 2022-06, Vol.298 (6), p.102003-102003, Article 102003

2022

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A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1

FEBS letters, 2021-01, Vol.595 (1), p.110-122

2021

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Targeting a critical step in fungal hexosamine biosynthesis

The Journal of biological chemistry, 2020-06, Vol.295 (26), p.8678-8691

2020

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Evidence for substrate-assisted catalysis in N -acetylphosphoglucosamine mutase

Biochemical journal, 2018-08, Vol.475 (15), p.2547-2557

2018

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Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells

Open biology, 2022, Vol.12 (1), p.210264

2022

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Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus

Molecular microbiology, 2021-07, Vol.116 (1), p.245-259

2021

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Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

Open biology, 2017-06, Vol.7 (6), p.170078

2017

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Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Science advances, 2024-06, Vol.10 (23), p.eadn7191

2024

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N‑Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

ACS chemical biology, 2015-06, Vol.10 (6), p.1425-1434

2015

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Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target

Bioscience reports, 2013-01, Vol.33 (5), p.689-699

2013

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Genetic and structural validation of Aspergillus fumigatus UDP‐N‐acetylglucosamine pyrophosphorylase as an antifungal target

Molecular microbiology, 2013-08, Vol.89 (3), p.479-493

2013

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A mechanism-inspired UDP- N -acetylglucosamine pyrophosphorylase inhibitor

RSC chemical biology, 2020-04, Vol.1 (1), p.13-25

2020

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Dual functionality of O-GlcNAc transferase is required for Drosophila development

Open biology, 2015-12, Vol.5 (12), p.150234-150234

2015

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In vitro anti-HIV, cytotoxicity and nutritional analysis of Trianthema portulacastrum L. (Aizoaceae)

BMC complementary medicine and therapies, 2024-01, Vol.24 (1), p.35-35, Article 35

2024

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A Novel Allosteric Inhibitor of the Uridine Diphosphate N‑Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

ACS chemical biology, 2013-09, Vol.8 (9), p.1981-1987

2013

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Planting Systems Affect Soil Microbial Communities and Enzymes Activities Differentially under Drought and Phosphorus Addition

Plants (Basel), 2022-01, Vol.11 (3), p.319

2022

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Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase

Biochemical journal, 2008-10, Vol.415 (2), p.217-223

2008

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A mechanism-inspired UDP--acetylglucosamine pyrophosphorylase inhibitor

RSC chemical biology, 2020-04, Vol.1 (1), p.13-25

2020

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Genetic and structural validation of A spergillus fumigatus UDP ‐ N ‐acetylglucosamine pyrophosphorylase as an antifungal target

Molecular microbiology, 2013-08, Vol.89 (3), p.479-493

2013

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Structure and substrate‐based inhibitor of Aspergillus fumigatus UDP‐N‐acetylglucosamine pyrophosphorylase (AfUAP1)

The FASEB journal, 2011-04, Vol.25, p.714.6-714.6

2011

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An ethnobotanical survey of medicinal plants used by traditional healers for the treatment of cancer in Hammanskraal and Winterveld, Tshwane Metropolitan Municipality, South Africa

African health sciences, 2021-12, Vol.21 (4), p.1746-53

2021

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Influence of Wind Direction on the Level of Trace Metals in Plants Collected around a Quarry Site in South Africa

Polish journal of environmental studies, 2019-01, Vol.28 (5), p.3385-3393

2019

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Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

N -myristoyltransferase inhibitors as new leads to treat sleeping sickness

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1

Targeting a critical step in fungal hexosamine biosynthesis

Evidence for substrate-assisted catalysis in N -acetylphosphoglucosamine mutase

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells

Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus

Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

N‑Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target

Genetic and structural validation of Aspergillus fumigatus UDP‐N‐acetylglucosamine pyrophosphorylase as an antifungal target

A mechanism-inspired UDP- N -acetylglucosamine pyrophosphorylase inhibitor

Dual functionality of O-GlcNAc transferase is required for Drosophila development

In vitro anti-HIV, cytotoxicity and nutritional analysis of Trianthema portulacastrum L. (Aizoaceae)

A Novel Allosteric Inhibitor of the Uridine Diphosphate N‑Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

Planting Systems Affect Soil Microbial Communities and Enzymes Activities Differentially under Drought and Phosphorus Addition

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase

A mechanism-inspired UDP--acetylglucosamine pyrophosphorylase inhibitor

Genetic and structural validation of A spergillus fumigatus UDP ‐ N ‐acetylglucosamine pyrophosphorylase as an antifungal target

Structure and substrate‐based inhibitor of Aspergillus fumigatus UDP‐N‐acetylglucosamine pyrophosphorylase (AfUAP1)

An ethnobotanical survey of medicinal plants used by traditional healers for the treatment of cancer in Hammanskraal and Winterveld, Tshwane Metropolitan Municipality, South Africa

Influence of Wind Direction on the Level of Trace Metals in Plants Collected around a Quarry Site in South Africa

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