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The Identification of a SIRT6 Activator from Brown Algae Fucus distichus

Marine drugs, 2017-06, Vol.15 (6), p.190

2017

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N-Acylethanolamines Bind to SIRT6

Chembiochem : a European journal of chemical biology, 2016-01, Vol.17 (1), p.77-81

2016

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Natural polyphenols as sirtuin 6 modulators

Scientific reports, 2018-03, Vol.8 (1), p.4163-11, Article 4163

2018

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Quercetin based derivatives as sirtuin inhibitors

Biomedicine & pharmacotherapy, 2019-03, Vol.111, p.1326-1333

2019

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Profiling the regulatory interplay of BET bromodomains and Sirtuins in cancer cell lines

Biomedicine & pharmacotherapy, 2022-03, Vol.147, p.112652-112652, Article 112652

2022

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Studying SIRT6 regulation using H3K56 based substrate and small molecules

European journal of pharmaceutical sciences, 2014-10, Vol.63, p.71-76

2014

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SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors

Pharmaceuticals (Basel, Switzerland), 2023-01, Vol.16 (1), p.127

2023

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Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities

Biomedicine & pharmacotherapy, 2020-11, Vol.131, p.110701-110701, Article 110701

2020

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Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells

Biomedicine & pharmacotherapy, 2021-06, Vol.138, p.111452-111452, Article 111452

2021

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Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle

Scientific reports, 2019-12, Vol.9 (1), p.19672-15, Article 19672

2019

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Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver

Current drug metabolism, 2013-01, Vol.14 (1), p.137-150

2013

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Common and Distinct Interactions of Chemical Inhibitors with Cytochrome P450 CYP1A2, CYP2A6 and CYP2B6 Enzymes

Drug metabolism letters, 2016-03, Vol.10 (1), p.56-64

2016

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CYP2A6: genetics, structure, regulation, and function

Drug metabolism and drug interactions, 2012-06, Vol.27 (2), p.73-88

2012

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Novel inhibitors of bromodomain and extra-terminal domain trigger cell death in breast cancer cell lines

Bioorganic & medicinal chemistry, 2024-10, Vol.112, p.117884, Article 117884

2024

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Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics

Journal of chemical information and modeling, 2022-05, Vol.62 (10), p.2571-2585

2022

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Impact of structurally diverse BET inhibitors on SIRT1

Gene, 2020-05, Vol.741, p.144558-144558, Article 144558

2020

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Sirtuin 6 (SIRT6) Activity Assays

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1436, p.259

2016

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TRPA1 Inhibition Effects by 3‑Phenylcoumarin Derivatives

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1221-1226

2024

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In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids

Chemical research in toxicology, 2015-04, Vol.28 (4), p.702-710

2015

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Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis

Drug metabolism and disposition, 2015-12, Vol.43 (12), p.1891-1904

2015

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Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H‑Pyrrolizin-7-yl)methanol

Chemical research in toxicology, 2014-11, Vol.27 (11), p.1950-1957

2014

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Quantitative insights for the design of substrate-based SIRT1 inhibitors

European journal of pharmaceutical sciences, 2014-08, Vol.59, p.12-19

2014

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Interactions of inhibitor molecules with the human CYP2E1 enzyme active site

European journal of pharmaceutical sciences, 2012-12, Vol.47 (5), p.996-1005

2012

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Rational design of novel CYP2A6 inhibitors

Bioorganic & medicinal chemistry, 2014-12, Vol.22 (23), p.6655-6664

2014

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Antifungal activities of novel non-azole molecules against S. cerevisiae and C. albicans

European journal of medicinal chemistry, 2012, Vol.47 (1), p.270-277

2012

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The Identification of a SIRT6 Activator from Brown Algae Fucus distichus

N-Acylethanolamines Bind to SIRT6

Natural polyphenols as sirtuin 6 modulators

Quercetin based derivatives as sirtuin inhibitors

Profiling the regulatory interplay of BET bromodomains and Sirtuins in cancer cell lines

Studying SIRT6 regulation using H3K56 based substrate and small molecules

SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors

Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities

Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells

Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver

Common and Distinct Interactions of Chemical Inhibitors with Cytochrome P450 CYP1A2, CYP2A6 and CYP2B6 Enzymes

CYP2A6: genetics, structure, regulation, and function

Novel inhibitors of bromodomain and extra-terminal domain trigger cell death in breast cancer cell lines

Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics

Impact of structurally diverse BET inhibitors on SIRT1

Sirtuin 6 (SIRT6) Activity Assays

TRPA1 Inhibition Effects by 3‑Phenylcoumarin Derivatives

In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids

Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis

Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H‑Pyrrolizin-7-yl)methanol

Quantitative insights for the design of substrate-based SIRT1 inhibitors

Interactions of inhibitor molecules with the human CYP2E1 enzyme active site

Rational design of novel CYP2A6 inhibitors

Antifungal activities of novel non-azole molecules against S. cerevisiae and C. albicans

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