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K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure

Journal of forensic sciences, 2013-11, Vol.58 (6), p.1676-1680

2013

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Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids

Drug metabolism and disposition, 2009-07, Vol.37 (7), p.1496

2009

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Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity

Pharmacology, biochemistry and behavior, 2020-08, Vol.195, p.172949-172949, Article 172949

2020

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Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

Molecules (Basel, Switzerland), 2020-10, Vol.25 (20), p.4820

2020

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Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Journal of molecular biology, 2007-06, Vol.369 (2), p.498-511

2007

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Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

Pharmacology research & perspectives, 2020-02, Vol.8 (1), p.e00561-n/a

2020

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Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

Analytical chemistry (Washington), 2011-06, Vol.83 (11), p.4228-4236

2011

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Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine

Analytical chemistry (Washington), 2011-08, Vol.83 (16), p.6381-6388

2011

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Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds

Forensic science international, 2013-12, Vol.233 (1), p.416-422

2013

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An Essential Role for Nuclear Receptors SXR/PXR in Detoxification of Cholestatic Bile Acids

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (6), p.3375-3380

2001

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Control of Steroid, Heme, and Carcinogen Metabolism by Nuclear Pregnane X Receptor and Constitutive Androstane Receptor

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (7), p.4150-4155

2003

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Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development

PloS one, 2016-12, Vol.11 (12), p.e0167240

2016

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Oxidative metabolism of synthetic cannabinoid STS-135 by recombinant P450S and human liver microsomes

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S28-S28

2019

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CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen

Biochemical and biophysical research communications, 2013-11, Vol.441 (2), p.339-343

2013

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Structure of UDP‐Glucuronosyltransferases in Membranes

Methods in Enzymology, 2005, Vol.400, p.116-147

2005

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Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

Frontiers in pharmacology, 2018-09, Vol.9, p.1084-1084

2018

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Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

Biopharmaceutics & drug disposition, 2006-05, Vol.27 (4), p.181-189

2006

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Effect of Retinoids on UDP-Glucuronosyltransferase 2B7 mRNA Expression in Caco-2 Cells

DRUG METABOLISM AND PHARMACOKINETICS, 2008-01, Vol.23 (5), p.364-372

2008

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Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity?

Life sciences (1973), 2014-02, Vol.97 (1), p.45-54

2014

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Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism

Drug Discovery Today, 2004-05, Vol.9 (10), p.442-449

2004

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Assessing Cytochrome P450 and UDP-Glucuronosyltransferase Contributions to Warfarin Metabolism in Humans

Chemical research in toxicology, 2009-07, Vol.22 (7), p.1239-1245

2009

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Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N ‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1 H ‐indole‐3‐carboxamide (STS‐135)

Pharmacology research & perspectives, 2020-02, Vol.8 (1)

2020

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Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10

Drug metabolism and disposition, 2009-04, Vol.37 (4), p.768

2009

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Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells

Journal of applied toxicology, 2014-11, Vol.34 (11), p.1188-1199

2014

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Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1143

2005

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K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure

Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids

Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine

Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds

An Essential Role for Nuclear Receptors SXR/PXR in Detoxification of Cholestatic Bile Acids

Control of Steroid, Heme, and Carcinogen Metabolism by Nuclear Pregnane X Receptor and Constitutive Androstane Receptor

Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development

Oxidative metabolism of synthetic cannabinoid STS-135 by recombinant P450S and human liver microsomes

CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen

Structure of UDP‐Glucuronosyltransferases in Membranes

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

Effect of Retinoids on UDP-Glucuronosyltransferase 2B7 mRNA Expression in Caco-2 Cells

Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity?

Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism

Assessing Cytochrome P450 and UDP-Glucuronosyltransferase Contributions to Warfarin Metabolism in Humans

Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N ‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1 H ‐indole‐3‐carboxamide (STS‐135)

Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10

Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells

Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity

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