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Practical Asymmetric Synthesis of Efavirenz (DMP 266), an HIV-1 Reverse Transcriptase Inhibitor

Journal of organic chemistry, 1998-11, Vol.63 (23), p.8536-8543

1998

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Stereoselective Process for a CCR3 Antagonist

Organic process research & development, 2006-03, Vol.10 (2), p.262-271

2006

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Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323

Journal of organic chemistry, 1996-01, Vol.61 (2), p.444-450

1996

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Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

Journal of medicinal chemistry, 1992-01, Vol.35 (1), p.38-47

1992

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One-Carbon Chain Extension of Esters to α-Chloroketones: A Safer Route without Diazomethane

Journal of organic chemistry, 2004-03, Vol.69 (5), p.1629-1633

2004

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Synthesis and receptor binding of enantiomeric N-substituted cis-N-[2-(3,4-dichlorophenyl)ethyl]-2-(1-pyrrolidinyl)cyclohexylamines as high-affinity .sigma. receptor ligands

Journal of medicinal chemistry, 1991-10, Vol.34 (10), p.3058-3065

1991

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Functional assessment and partial characterization of [ 3H](+)-pentazocine binding sites on cells of the immune system

Journal of neuroimmunology, 1991-12, Vol.35 (1), p.153-166

1991

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Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors through Alteration of the Piperazine Ring of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)

Journal of medicinal chemistry, 1996-11, Vol.39 (24), p.4704-4716

1996

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The [2 + 3] and [3 + 4] annulation of enones. Enantiocontrolled total synthesis of (-)-retigeranic acid

Journal of the American Chemical Society, 1989-08, Vol.111 (17), p.6691-6707

1989

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Synthesis of HIV-1 Reverse Transcriptase Inhibitor DMP 266

Synthetic communications, 1997-12, Vol.27 (24), p.4373-4384

1997

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Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediamines as .sigma. receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes

Journal of medicinal chemistry, 1992-11, Vol.35 (23), p.4334-4343

1992

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The [2 + 3] and [3 + 4] annulation of enones. Enantiocontrolled total synthesis of (-)-retigeranic acid [Erratum to document cited in CA111(11):97589v]

Journal of the American Chemical Society, 1989-12, Vol.111 (25), p.9136-9136

1989

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Synthesis and receptor binding properties of fluoro- and iodo-substituted high-affinity .sigma.-receptor ligands: identification of potential PET and SPECT .sigma.-receptor imaging agents

Journal of medicinal chemistry, 1992-06, Vol.35 (12), p.2221-2230

1992

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A Practical Triphenylcarbenium Tetrafluoroborate Mediated One-Pot Synthesis of 1-Substituted N-Alkyl-1,2,3,4-tetrahydroisoquinolines

Synthesis (Stuttgart), 1992, Vol.1992 (9), p.887-890

1992

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Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity .sigma. receptor ligands. Identification of a new class of highly potent and selective .sigma. receptor probes

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.3100-3110

1990

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Menthyl 2-bromocrotonate and menthyl 4-bromocrotonate: reagents for chiral vinylogous Darzens and Reformatsky reactions

Journal of organic chemistry, 1987-09, Vol.52 (19), p.4397-4399

1987

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A Practical Synthesis, Optical Resolution and Determination of Absolute Configuration of Enantiomerically Pure 1S,2R-(+)- and 1R,2S-(-)-cis-2-(1-Pyrrolidinyl)cyclohexylamines: Important Precursor for a New Class of Sigma-Receptor Ligands and Anticonvulsant Drugs

Heterocycles, 1990, Vol.31 (10), p.1837

1990

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A practical synthesis, optical resolution and determination of absolute configuration of enantiomerically pure 1S,2R-(+)- and 1R,2S-(-)-CIS-2(1-pyrrolidinyl)cyclohexylamines : important precursors for a new class of sigma-receptor ligands and anticonvulsant drugs

Heterocycles, 1990-10, Vol.31 (10), p.1837-1846

1990

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Menthyl 2-bromocrotonate and menthyl 4-bromocrotonate: reagents for chiral vinylogous Darzen and Reformatsky reactions

Journal of organic chemistry, 1987-09, Vol.52 (19), p.4397-4399

1987

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Vinylcyclopropanation of enones in (2+3) cyclopentene annulation. Application to the total synthesis of (-)-retigeranic acid

Radesca, Lilian Alicia

1989

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New vinylcyclopropanation methodology and reagents for potential [2 + 3] cyclopentene, dihydrofuran, and pyrroline annulations

Journal of organic chemistry, 1986-11, Vol.51 (24), p.4746-4748

1986

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Short, enantioselective synthesis of (−)-retigeranc acid via [2+3] annulation

Tetrahedron letters, 1988, Vol.29 (27), p.3283-3286

1988

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One-Carbon Chain Extension of Esters to α-Chloroketones: A Safer Route Without Diazomethane

ChemInform, 2004-07, Vol.35 (29), p.no-no

2004

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General Method of Synthesis for Natural Long-Chain β/-Diketones

Journal of natural products (Washington, D.C.), 1987-07, Vol.50 (4), p.646-649

1987

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Practical Asymmetric Synthesis of Efavirenz (DMP 266), an HIV-1 Reverse Transcriptase Inhibitor

Stereoselective Process for a CCR3 Antagonist

Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323

Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

One-Carbon Chain Extension of Esters to α-Chloroketones: A Safer Route without Diazomethane

Synthesis and receptor binding of enantiomeric N-substituted cis-N-[2-(3,4-dichlorophenyl)ethyl]-2-(1-pyrrolidinyl)cyclohexylamines as high-affinity .sigma. receptor ligands

Functional assessment and partial characterization of [ 3H](+)-pentazocine binding sites on cells of the immune system

Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors through Alteration of the Piperazine Ring of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)

The [2 + 3] and [3 + 4] annulation of enones. Enantiocontrolled total synthesis of (-)-retigeranic acid

Synthesis of HIV-1 Reverse Transcriptase Inhibitor DMP 266

Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediamines as .sigma. receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes

The [2 + 3] and [3 + 4] annulation of enones. Enantiocontrolled total synthesis of (-)-retigeranic acid [Erratum to document cited in CA111(11):97589v]

Synthesis and receptor binding properties of fluoro- and iodo-substituted high-affinity .sigma.-receptor ligands: identification of potential PET and SPECT .sigma.-receptor imaging agents

A Practical Triphenylcarbenium Tetrafluoroborate Mediated One-Pot Synthesis of 1-Substituted N-Alkyl-1,2,3,4-tetrahydroisoquinolines

Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity .sigma. receptor ligands. Identification of a new class of highly potent and selective .sigma. receptor probes

Menthyl 2-bromocrotonate and menthyl 4-bromocrotonate: reagents for chiral vinylogous Darzens and Reformatsky reactions

A Practical Synthesis, Optical Resolution and Determination of Absolute Configuration of Enantiomerically Pure 1S,2R-(+)- and 1R,2S-(-)-cis-2-(1-Pyrrolidinyl)cyclohexylamines: Important Precursor for a New Class of Sigma-Receptor Ligands and Anticonvulsant Drugs

A practical synthesis, optical resolution and determination of absolute configuration of enantiomerically pure 1S,2R-(+)- and 1R,2S-(-)-CIS-2(1-pyrrolidinyl)cyclohexylamines : important precursors for a new class of sigma-receptor ligands and anticonvulsant drugs

Menthyl 2-bromocrotonate and menthyl 4-bromocrotonate: reagents for chiral vinylogous Darzen and Reformatsky reactions

Vinylcyclopropanation of enones in (2+3) cyclopentene annulation. Application to the total synthesis of (-)-retigeranic acid

New vinylcyclopropanation methodology and reagents for potential [2 + 3] cyclopentene, dihydrofuran, and pyrroline annulations

Short, enantioselective synthesis of (−)-retigeranc acid via [2+3] annulation

One-Carbon Chain Extension of Esters to α-Chloroketones: A Safer Route Without Diazomethane

General Method of Synthesis for Natural Long-Chain β/-Diketones

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