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The Catalytic Mechanism of a Natural Diels–Alderase Revealed in Molecular Detail

Journal of the American Chemical Society, 2016-05, Vol.138 (19), p.6095-6098

2016

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The Streptococcus gordonii Adhesin CshA Protein Binds Host Fibronectin via a Catch-Clamp Mechanism

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1538-1549

2017

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Derivation of a Precise and Consistent Timeline for Antibiotic Development

Antibiotics (Basel), 2022-09, Vol.11 (9), p.1237

2022

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A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge

Marine drugs, 2021-02, Vol.19 (2), p.105

2021

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Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases

Biotechnology letters, 2014-05, Vol.36 (5), p.877-888

2014

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Correction: Back et al. A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge. Mar. Drugs 2021, 19 , 105

Marine drugs, 2023-03, Vol.21 (4), p.214

2023

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BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre

Biochemical Society transactions, 2016-06, Vol.44 (3), p.689-691

2016

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Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub

Science (American Association for the Advancement of Science), 2008-10, Vol.322 (5898), p.92-96

2008

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Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology

Frontiers in bioengineering and biotechnology, 2020-08, Vol.8, p.942-942

2020

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The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products

Antibiotics (Basel), 2020-08, Vol.9 (8), p.509

2020

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Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei

PloS one, 2009-05, Vol.4 (5), p.e5582-e5582

2009

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Studies of recombinant TWA1 reveal constitutive dimerization

Bioscience reports, 2017-02, Vol.37 (1)

2017

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Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13256-13264

2005

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Diversity and structure of the deep-sea sponge microbiome in the equatorial Atlantic Ocean

Microbiology (Society for General Microbiology), 2024-07, Vol.170 (7)

2024

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Structure and Function of the α‐Hydroxylation Bimodule of the Mupirocin Polyketide Synthase

Angewandte Chemie International Edition, 2023-11, Vol.62 (47), p.e202312514-n/a

International ed. in English, 2023

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Towards machine learning approaches for predicting the self-healing efficiency of materials

Computational materials science, 2019-10, Vol.168, p.180-187

2019

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Expression, purification and preliminary characterisation of the choline transporter LicB from opportunistic bacterial pathogens

Protein expression and purification, 2022-02, Vol.190, p.106011-106011, Article 106011

2022

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Delineation of the complete reaction cycle of a natural Diels-Alderase

Chemical science (Cambridge), 2024-07, Vol.15 (29), p.11572-11583

2024

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The Assembly Line Enzymology of Polyketide Biosynthesis

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1401, p.31

2016

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Domain shuffling of a highly mutable ligand‐binding fold drives adhesin generation across the bacterial kingdom

Proteins, structure, function, and bioinformatics, 2023-08, Vol.91 (8), p.1007-1020

2023

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The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis

Angewandte Chemie International Edition, 2023-01, Vol.62 (3), p.e202213053-n/a

International ed. in English, 2023

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Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis

Chemical science (Cambridge), 2024-08, Vol.15 (34), p.14009-14015

2024

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Long-Term Subclinical Carrier State Precedes Scrapie Replication and Adaptation in a Resistant Species: Analogies to Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease in Humans

Journal of Virology, 2001-11, Vol.75 (21), p.10106-10112

2001

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Enzyme‐catalysed polymer cross‐linking: Biocatalytic tools for chemical biology, materials science and beyond

Biopolymers, 2020-09, Vol.111 (9), p.e23390-n/a

2020

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Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases

Chembiochem : a European journal of chemical biology, 2023-07, Vol.24 (14), p.e202300382-n/a

2023

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The Catalytic Mechanism of a Natural Diels–Alderase Revealed in Molecular Detail

The Streptococcus gordonii Adhesin CshA Protein Binds Host Fibronectin via a Catch-Clamp Mechanism

Derivation of a Precise and Consistent Timeline for Antibiotic Development

A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge

Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases

Correction: Back et al. A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge. Mar. Drugs 2021, 19 , 105

BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre

Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub

Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology

The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products

Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei

Studies of recombinant TWA1 reveal constitutive dimerization

Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme

Diversity and structure of the deep-sea sponge microbiome in the equatorial Atlantic Ocean

Structure and Function of the α‐Hydroxylation Bimodule of the Mupirocin Polyketide Synthase

Towards machine learning approaches for predicting the self-healing efficiency of materials

Expression, purification and preliminary characterisation of the choline transporter LicB from opportunistic bacterial pathogens

Delineation of the complete reaction cycle of a natural Diels-Alderase

The Assembly Line Enzymology of Polyketide Biosynthesis

Domain shuffling of a highly mutable ligand‐binding fold drives adhesin generation across the bacterial kingdom

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis

Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis

Long-Term Subclinical Carrier State Precedes Scrapie Replication and Adaptation in a Resistant Species: Analogies to Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease in Humans

Enzyme‐catalysed polymer cross‐linking: Biocatalytic tools for chemical biology, materials science and beyond

Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases

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