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High-resolution structure and strain comparison of infectious mammalian prions

Molecular cell, 2021-11, Vol.81 (21), p.4540-4551.e6

2021

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Microglia Are Critical in Host Defense against Prion Disease

Journal of virology, 2018-08, Vol.92 (15)

2018

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Transmission studies of chronic wasting disease to transgenic mice overexpressing human prion protein using the RT-QuIC assay

Veterinary research (Paris), 2019-01, Vol.50 (1), p.6-6, Article 6

2019

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Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques

Journal of virology, 2018-07, Vol.92 (14)

2018

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Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains

Nature communications, 2022-07, Vol.13 (1), p.4005-7, Article 4005

2022

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CD11c is not required by microglia to convey neuroprotection after prion infection

PloS one, 2023-11, Vol.18 (11), p.e0293301-e0293301

2023

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RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection

Molecular brain, 2020-05, Vol.13 (1), p.71-71, Article 71

2020

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Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

PLoS pathogens, 2022-11, Vol.18 (11), p.e1010947

2022

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Inactivation of chronic wasting disease prions using sodium hypochlorite

PloS one, 2019-10, Vol.14 (10), p.e0223659-e0223659

2019

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Toll-like receptor 2 confers partial neuroprotection during prion disease

PloS one, 2018-12, Vol.13 (12), p.e0208559-e0208559

2018

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Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

Scientific reports, 2021-03, Vol.11 (1), p.5165-5165, Article 5165

2021

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Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays

PLoS pathogens, 2010-12, Vol.6 (12), p.e1001217-e1001217

2010

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Lack of Transmission of Chronic Wasting Disease Prions to Human Cerebral Organoids

Emerging infectious diseases, 2024-06, Vol.30 (6), p.1193-1202

2024

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The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

PloS one, 2024-02, Vol.19 (2), p.e0298095-e0298095

2024

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Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

PLoS pathogens, 2016-04, Vol.12 (4), p.e1005551-e1005551

2016

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Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

Veterinary research (Paris), 2022-12, Vol.53 (1), p.111-111, Article 111

2022

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Chronic wasting disease agents in nonhuman primates

Emerging infectious diseases, 2014-05, Vol.20 (5), p.833-837

2014

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Efficacy of Wex-cide 128 disinfectant against multiple prion strains

PloS one, 2023-08, Vol.18 (8), p.e0290325-e0290325

2023

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Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14083-14087

2010

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Poor Vector Competence of Fleas and the Evolution of Hypervirulence in Yersinia pestis

The Journal of infectious diseases, 2005-06, Vol.191 (11), p.1907-1912

2005

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Microglia have limited influence on early prion pathogenesis, clearance, or replication

PloS one, 2022-10, Vol.17 (10), p.e0276850-e0276850

2022

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Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein

Neurobiology of disease, 2020-10, Vol.144, p.105057-105057, Article 105057

2020

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Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia

Journal of neuroinflammation, 2021-09, Vol.18 (1), p.194-194, Article 194

2021

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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

Acta neuropathologica communications, 2019-06, Vol.7 (1), p.90-90, Article 90

2019

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Early preclinical detection of prions in the skin of prion-infected animals

Nature communications, 2019-01, Vol.10 (1), p.247-247, Article 247

2019

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High-resolution structure and strain comparison of infectious mammalian prions

Microglia Are Critical in Host Defense against Prion Disease

Transmission studies of chronic wasting disease to transgenic mice overexpressing human prion protein using the RT-QuIC assay

Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques

Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains

CD11c is not required by microglia to convey neuroprotection after prion infection

RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection

Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

Inactivation of chronic wasting disease prions using sodium hypochlorite

Toll-like receptor 2 confers partial neuroprotection during prion disease

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays

Lack of Transmission of Chronic Wasting Disease Prions to Human Cerebral Organoids

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

Chronic wasting disease agents in nonhuman primates

Efficacy of Wex-cide 128 disinfectant against multiple prion strains

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

Poor Vector Competence of Fleas and the Evolution of Hypervirulence in Yersinia pestis

Microglia have limited influence on early prion pathogenesis, clearance, or replication

Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein

Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

Early preclinical detection of prions in the skin of prion-infected animals

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