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Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

Science (American Association for the Advancement of Science), 2004-12, Vol.306 (5705), p.2261-2264

2004

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Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity

Diabetes (New York, N.Y.), 2014-07, Vol.63 (7), p.2415-2431

2014

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A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts

Thyroid (New York, N.Y.), 2012-08, Vol.22 (8), p.839

2012

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Discovery of Novel Agonists and Antagonists of the Free Fatty Acid Receptor 1 (FFAR1) Using Virtual Screening

Journal of medicinal chemistry, 2008-02, Vol.51 (3), p.625-633

2008

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Human Pancreatic Precursor Cells Secrete FGF2 to Stimulate Clustering into Hormone-Expressing Islet-like Cell Aggregates

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (12), p.7117-7122

2003

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Identification of Residues Important for Agonist Recognition and Activation in GPR40

The Journal of biological chemistry, 2007-10, Vol.282 (40), p.29248-29255

2007

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Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (30), p.12471-12476

2009

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Bidirectional, Iterative Approach to the Structural Delineation of the Functional “Chemoprint” in GPR40 for Agonist Recognition

Journal of medicinal chemistry, 2007-06, Vol.50 (13), p.2981-2989

2007

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Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets

Journal of cell science, 2012-09, Vol.125 (Pt 17), p.4067-4076

2012

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Discovery of Diverse Thyroid Hormone Receptor Antagonists by High-Throughput Docking

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (12), p.7354-7359

2003

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A Low Molecular Weight Agonist Signals by Binding to the Transmembrane Domain of Thyroid-stimulating Hormone Receptor (TSHR) and Luteinizing Hormone/Chorionic Gonadotropin Receptor (LHCGR)

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.9841-9844

2006

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Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Frontiers in endocrinology (Lausanne), 2012, Vol.3, p.120-120

2012

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Evaluation of gene expression measurements from commercial microarray platforms

Nucleic acids research, 2003-10, Vol.31 (19), p.5676-5684

2003

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Rational Discovery of Novel Nuclear Hormone Receptor Antagonists

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (3), p.1008-1013

2000

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Human Islet‐Derived Precursor Cells Are Mesenchymal Stromal Cells That Differentiate and Mature to Hormone‐Expressing Cells In Vivo

Stem cells (Dayton, Ohio), 2007-12, Vol.25 (12), p.3215-3222

2007

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Are Better Islet Cell Precursors Generated by Epithelial-to-Mesenchymal Transition?

Cell cycle (Georgetown, Tex.), 2005-03, Vol.4 (3), p.380-382

2005

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Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice

Neuropsychopharmacology (New York, N.Y.), 2013-05, Vol.38 (6), p.950-956

2013

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The Human Insulin Gene Displays Transcriptionally Active Epigenetic Marks in Islet‐Derived Mesenchymal Precursor Cells in the Absence of Insulin Expression

Stem cells (Dayton, Ohio), 2007-12, Vol.25 (12), p.3223-3233

2007

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A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

Endocrinology (Philadelphia), 2008-12, Vol.149 (12), p.5945-5950

2008

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TRH-Receptor-Type-2-Deficient Mice are Euthyroid and Exhibit Increased Depression and Reduced Anxiety Phenotypes

Neuropsychopharmacology (New York, N.Y.), 2009-05, Vol.34 (6), p.1601-1608

2009

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Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor

The FASEB journal, 2008-08, Vol.22 (8), p.2798-2808

2008

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TLS (Translocated-in-Liposarcoma) Is a High-Affinity Interactor for Steroid, Thyroid Hormone, and Retinoid Receptors

Molecular endocrinology (Baltimore, Md.), 1998-01, Vol.12 (1), p.4-18

1998

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Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells

Molecular and cellular endocrinology, 2007-05, Vol.270 (1), p.87-93

2007

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Constitutively Active Thyrotropin and Thyrotropin-Releasing Hormone Receptors and Their Inverse Agonists

Methods in Enzymology, 2010, Vol.485, p.147-160

2010

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Insulin but Not Glucagon Gene is Silenced in Human Pancreas‐Derived Mesenchymal Stem Cells

Stem cells (Dayton, Ohio), 2009-11, Vol.27 (11), p.2703-2711

2009

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Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity

A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts

Discovery of Novel Agonists and Antagonists of the Free Fatty Acid Receptor 1 (FFAR1) Using Virtual Screening

Human Pancreatic Precursor Cells Secrete FGF2 to Stimulate Clustering into Hormone-Expressing Islet-like Cell Aggregates

Identification of Residues Important for Agonist Recognition and Activation in GPR40

Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice

Bidirectional, Iterative Approach to the Structural Delineation of the Functional “Chemoprint” in GPR40 for Agonist Recognition

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets

Discovery of Diverse Thyroid Hormone Receptor Antagonists by High-Throughput Docking

A Low Molecular Weight Agonist Signals by Binding to the Transmembrane Domain of Thyroid-stimulating Hormone Receptor (TSHR) and Luteinizing Hormone/Chorionic Gonadotropin Receptor (LHCGR)

Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor

Evaluation of gene expression measurements from commercial microarray platforms

Rational Discovery of Novel Nuclear Hormone Receptor Antagonists

Human Islet‐Derived Precursor Cells Are Mesenchymal Stromal Cells That Differentiate and Mature to Hormone‐Expressing Cells In Vivo

Are Better Islet Cell Precursors Generated by Epithelial-to-Mesenchymal Transition?

Thyrotropin-releasing hormone receptor type 1 (TRH-R1), not TRH-R2, primarily mediates taltirelin actions in the CNS of mice

The Human Insulin Gene Displays Transcriptionally Active Epigenetic Marks in Islet‐Derived Mesenchymal Precursor Cells in the Absence of Insulin Expression

A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

TRH-Receptor-Type-2-Deficient Mice are Euthyroid and Exhibit Increased Depression and Reduced Anxiety Phenotypes

Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor

TLS (Translocated-in-Liposarcoma) Is a High-Affinity Interactor for Steroid, Thyroid Hormone, and Retinoid Receptors

Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells

Constitutively Active Thyrotropin and Thyrotropin-Releasing Hormone Receptors and Their Inverse Agonists

Insulin but Not Glucagon Gene is Silenced in Human Pancreas‐Derived Mesenchymal Stem Cells

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