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The Implementation in Context (ICON) Framework: A meta-framework of context domains, attributes and features in healthcare

Health research policy and systems, 2023-08, Vol.21 (1), p.81-81, Article 81

2023

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Physical dependence liability of retigabine in rats

Drug and alcohol dependence, 2015-01, Vol.146, p.e2-e2

2015

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Discovery of Novel 6,6-Heterocycles as Transient Receptor Potential Vanilloid (TRPV1) Antagonists

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3330-3348

2010

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Novel lactam NK1 antagonists with anti-emetic activity

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1197-1201

2006

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Novel lactam NK 1 antagonists with anti-emetic activity

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (5), p.1197-1201

2006

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Novel lactam NK sub(1) antagonists with anti-emetic activity

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (5), p.1197-1201

2006

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Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets

Drug metabolism and disposition, 2003-06, Vol.31 (6), p.785

2003

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4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1759-1762

2002

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4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1755

2002

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4,4-Disubstituted cyclohexylamine NK1 receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1755-1758

2002

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4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists II

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (13), p.1759

2002

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4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists I

Bioorganic & medicinal chemistry letters, 2002, Vol.12 (13), p.1755-1758

2002

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4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists II

Bioorganic & medicinal chemistry letters, 2002, Vol.12 (13), p.1759-1762

2002

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An Orally Active, Water-Soluble Neurokinin-1 Receptor Antagonist Suitable for Both Intravenous and Oral Clinical Administration

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4296-4299

2001

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2-Aryl indole NK1 receptor antagonists : Optimisation of the 2-aryl ring and the indole nitrogen substituent

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1237-1240

2001

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2-Aryl indole NK 1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (9), p.1237-1240

2001

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Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

Journal of medicinal chemistry, 1998-11, Vol.41 (23), p.4607-4614

1998

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In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists

European journal of pharmacology, 1997-05, Vol.326 (2-3), p.201-209

1997

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In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK 1 receptor antagonists

European journal of pharmacology, 1997, Vol.326 (2), p.201-209

1997

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The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

European journal of pharmacology, 1993-11, Vol.250 (1), p.R5-R6

1993

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The tachykinin NK 1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

European journal of pharmacology, 1993, Vol.250 (1), p.R5-R6

1993

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Biological And Medical Sciences
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Medical Sciences
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Pharmacology. Drug Treatments
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The Implementation in Context (ICON) Framework: A meta-framework of context domains, attributes and features in healthcare

Physical dependence liability of retigabine in rats

Discovery of Novel 6,6-Heterocycles as Transient Receptor Potential Vanilloid (TRPV1) Antagonists

Novel lactam NK1 antagonists with anti-emetic activity

Novel lactam NK 1 antagonists with anti-emetic activity

Novel lactam NK sub(1) antagonists with anti-emetic activity

Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets

4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I

4,4-Disubstituted cyclohexylamine NK1 receptor antagonists I

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists II

4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists I

4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists II

An Orally Active, Water-Soluble Neurokinin-1 Receptor Antagonist Suitable for Both Intravenous and Oral Clinical Administration

2-Aryl indole NK1 receptor antagonists : Optimisation of the 2-aryl ring and the indole nitrogen substituent

2-Aryl indole NK 1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK 1 receptor antagonists

The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

The tachykinin NK 1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

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